Nitrification Couples Microbial CO2 Fixation to Warming and Drought Responses in Alpine Grassland Soils

Microbial CO2 fixation in alpine grassland soils is highly sensitive to warming and drought. Nitrogen inputs from grazing may stimulate autotrophic nitrifiers, including ammonia-oxidizing archaea (AOA...

doi.org

Resistance to the conjugation inhibitor AZT reveals mating partner incompatibility during plasmid transfer

Plasmid-mediated dissemination of antibiotic resistance genes (ARGs) is a major driver of antimicrobial resistance (AMR). The nucleoside analogue zidovudine (azidothymidine, AZT) has emerged as a prom...

doi.org

Cycles of contamination and recovery: Combined sewer overflows drive acute but transient antimicrobial resistance exposure in an urban stream

Combined sewer overflows (CSOs) are a major pathway for untreated wastewater into urban streams, yet their role in shaping antimicrobial resistance (AMR) dynamics remains poorly understood. Here, we u...

doi.org

Reusable immobilised quaternary ammonium particles reduce microbial and resistome burdens without promoting resistance selection during wastewater post-treatment - npj Clean Water

npj Clean Water - Reusable immobilised quaternary ammonium particles reduce microbial and resistome burdens without promoting resistance selection during wastewater post-treatment

nature.com

biorxiv.org

doi.org

Effect of biofilm lifestyle caused by water matric potential on invasion of exogenous plasmid

Abstract. Conjugal plasmid transfer is an efficient mechanism for gene exchange among bacteria. Most bacteria exist in biofilms encased in extracellular po

doi.org

Antibiotics or Heavy Metals in Livestock Wastewater: Which One Is the Main Driver for the Development and Spread of Antibiotic Resistance under Coexposure?

Antibiotics and heavy metals are widely used in livestock farming to promote animal health and growth, leading to their frequent co-occurrence as contaminants in livestock wastewater. However, their r...

pubs.acs.org

doi.org

Impact of human activities on groundwater biogeochemical cycles and microbial communities: Insights from metagenomic analysis

Anthropogenic nitrogen pollution poses a systemic threat to microbial interaction networks and biogeochemical cycling in groundwater ecosystems, yet t…

sciencedirect.com

Cefiderocol resistance genes identified in environmental samples using functional metagenomics

Abstract. Antibiotic resistance poses a global public health threat, which can originate from the transfer of environmental antibiotic resistance genes to

academic.oup.com

Client Challenge

doi.org

Combined exposure of enrofloxacin and disinfection byproducts under environmentally relevant concentrations enhances antibiotic resistance risks in livestock wastewater

Livestock wastewater is a crucial source of antibiotic resistance. However, the impact of disinfection byproducts (DBPs), stemming from disinfectants …

sciencedirect.com

Geographics and bacterial networks differently shape the acquired and latent global sewage resistomes - Nature Communications

Antimicrobial resistance genes that have been mobilized between bacterial species represent a subset of the naturally occurring resistome. Here, the authors compare the abundance, diversity and geogra...

doi.org

CFD and OCT-Based Optimisation of Impeller-Induced Shear Stress on Membrane Surfaces in a Circular Test Cell

This study investigates the distribution of shear stress in a lab-scale membrane bioreactor consisting of a 56 mm-diameter cylindrical test cell, a 0.…

sciencedirect.com

ONE-Bridge project | Conference | Workshops

Fostering collaboration and addressing the interconnected challenges at the interface of human, animal, and environmental health.

one-bridge.iwaterfood.gr

Microbial risks triggered by oral administration of antibiotics in fish aquaculture persist long after the legally mandated antibiotic withdrawal time - Nature Water

Florfenicol treatment substantially increased the abundance and mobility of antibiotic resistance genes (ARGs) in the common carp gut microbiome. The resistome and mobilome profiles failed to return t...

nature.com

Genomic resistance in historical clinical isolates increased in frequency and mobility after the age of antibiotics

Antibiotic resistance is frequently observed shortly after the clinical introduction of an antibiotic. Whether and how frequently that resistance occurred before the introduction is harder to determin...

microbiologyresearch.org

Towards the integration of antibiotic resistance gene mobility into environmental surveillance and risk assessment - npj Antimicrobials and Resistance

npj Antimicrobials and Resistance - Towards the integration of antibiotic resistance gene mobility into environmental surveillance and risk assessment

nature.com

Selective spread of mobile antibiotic resistance genes in wastewater microbiomes driven by the non-antibiotic pharmaceutical carbamazepine

Carbamazepine (CBZ), a widely used anticonvulsant, is a persistent aquatic micropollutant that withstands biodegradation and accumulates in wastewater-impacted environments. While non-antibiotic pharm...

biorxiv.org

Ecology-based approach to predict no-effect antibiotic concentrations for minimizing environmental selection of resistance

Abstract. Selection for antibiotic resistance has been demonstrated at low, environmentally relevant antibiotic concentrations. The concept of minimum sele

academic.oup.com

Harnessing phage consortia to mitigate the soil antibiotic resistome by targeting keystone taxa Streptomyces - Microbiome

Background Antimicrobial resistance poses a substantial and growing threat to global health. While antibiotic resistance genes (ARGs) are tracked most closely in clinical settings, their spread remain...

microbiomejournal.biomedcentral.com

Evaluation of a Low-Cost Active Air Sampler for the Surveillance of Airborne Transmission of Antibiotic Resistance Genes Using a Municipal Wastewater Treatment Plant as a Case Study

Assessing the risks associated with antibiotic resistance genes (ARGs) in the environment remains challenging due to limited understanding of their distribution and transmission across various media, ...

pubs.acs.org

Environmental reservoir of resistance genes for the last resort antibiotic Cefiderocol.

Antibiotic resistance poses a global public health threat. Cefiderocol, a recently introduced siderophore cephalosporin, employs a 'Trojan Horse' mechanism by exploiting bacterial iron uptake systems ...

biorxiv.org

Horizontal gene transfer of molecular weapons can reshape bacterial competition

Bacteria use molecular weapons such as toxins to outcompete rivals, but their horizontal gene transfer can undermine this advantage. This study shows that horizontal gene transfer of toxin plasmids is...

journals.plos.org

The link between antibiotic resistance level and soil physico-chemical properties

Antimicrobial resistance (AMR) is a critical global health concern. While AMR research has primarily focused on medical and veterinary settings, the spread of antibiotic-resistant bacteria (ARB) and a...

doi.org