“Controlled chaos” “Like a Gilbert and Sullivan patter song without the singing” “I never knew a human could sweat that much” Intrigued? Then sign up for Cameron Wyatt's show 'It all went wrong at legs': Saturday 22 August, 1.45pm: edin.ac/4fMZ2D0 Tuesday 25 August, 5.35pm: edin.ac/4wBtXJP

Great to see the publication of this paper in @nature.com involving @mstaylor.bsky.social as part of an international team of researchers.

Martin Taylor@mstaylor.bsky.social · last wk.

To what extent is cancer development deterministic? Does the germline genome affect that predictability? We re-ran cancer evolution to answer these questions. www.nature.com/articles/s41...

#ThrowbackThursday - It's amazing to see how our buildings have developed over the years to accommodate the growth of the Institute and its research facilities. Keep an eye out about how you can learn more at Doors Open Day at the end of September 👀

new out in Nature www.nature.com/articles/s41...

Genetic background sets the trajectory of experimental cancer evolution - Nature

Experimentally replaying tumour evolution in divergent mouse strains reveals the importance of interactions between genetic ancestry and acquired cancer-driving mutations in shaping the earliest stage...

nature.com

Congratulations to @wbickmor.bsky.social lab for being selected as a Centre of Excellence by the CdLS Foundation, a national non-profit organisation supporting individuals with Cornelia de Lange Syndrome (CdLS) and their families. 🎉

Wendy Bickmore@wbickmor.bsky.social · last mo.

Very honoured that the lab has been selected as the first UK Center for Excellence by the CdLS foundation www.cdlsusa.org/centers-for-.... We aim to advance knowledge about this genetic condition and to explore similarities to other rare genetic disorders that affect gene regulation.

New Publication: CARMN fusions and PDGFRB mutations highlight key differences amongst cutaneous tumors with myopericytic differentiation @cruk-si.bsky.social @uoe-igc.bsky.social #angioleiomyoma #CARMN #glomustumor #myopericytoma www.sciencedirect.com/science/arti...

CARMN fusions and PDGFRB mutations highlight key differences among cutaneous tumors with myopericytic differentiation

All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.

sciencedirect.com

Biotech spinout Pheno Therapeutics Ltd has announced its lead therapeutic candidate for MS has been cleared as an Investigational New Drug (IND) by the US Food and Drug Administration (FDA), allowing it to move to clinical trials. ➡️ Read more edinburgh-innovations.ed.ac.uk/news/spinout...

New Publication: A transcriptomic microglia taxonomy across mouse and human pathologies @uoe-igc.bsky.social www.nature.com/articles/s41...

A transcriptomic microglia taxonomy across mouse and human pathologies - Nature Immunology

In this atlas paper, the authors provide a transcriptomic and spatial taxonomy of myeloid cells in the central nervous system of mice and humans in health and pathology.

nature.com

Have you heard of cholangiocarcinoma? This rare and aggressive form of cancer originates in the bile ducts and is one of the conditions @cancerresearchuk.org Senior Fellow Luke Boulter is investigating in his lab. Find out more about this condition and his research 👉

IGC Research in a Nutshell Dr Luke Boulter

Dr Luke Boulter Institute of Genetics and Cancer.

edin.ac

Calling all alumni of the MRC Human Genetics Unit at @edinburgh-uni.bsky.social. Please join us on 23 September to mark the last ever intake of PhD students to the MRC HGU, and to celebrate the achievements of many of our alumni and the current PhD cohort. Register here 👉 edin.ac/4uLXn6m

A new study has identified a rare genetic condition which causes individuals to age at a faster rate than normal, shining a light on the mechanisms of aging. This study was jointly supervised by Kevin Myant, Elaine Dzierzak, Martin Reijns, @sproullab.bsky.social and Andrew Jackson edin.ac/4vDOCfM

Rare ageing disorder links ‘biological clock’ to disease | Institute of Genetics and Cancer | Institute of Genetics and Cancer

Scientists have discovered a rare genetic condition which causes people to age at a much faster rate, offering fresh insights into the ageing process.

edin.ac

The @edfringe.bsky.social is fast approaching - and the chance to catch Cameron Wyatt's show at The Provocateurs: It all went wrong at legs at @standcomedyclub.bsky.social. Find out more and book tickets 👉 22 August: edin.ac/4evs8q2 25 August: edin.ac/4vqHjrO

The Provocateurs: It all went wrong at legs / Age-old story - The Stand Comedy Club

The Provocateurs: It all went wrong at legs / Age-old storyDr Cameron Wyatt (The University of Edinburgh), declares that zebrafish are the superior organism....

edin.ac

Congratulations to Mark Arends, Peter Bankhead & the QuPath Team who won The Royal College of Pathologists (RCPath) Team Award for Innovation, Technology or Development of AI. QuPath is one of the world’s most widely used image analysis platforms for digital pathology. Read more:

QuPath

QuPath is cross-platform, user-friendly open source software for digital pathology and whole slide image analysis, written using JavaFX. QuPath has also been designed to be developer-friendly, and…

qupath.github.io

A genetic difference carried by nearly 1 in 3 people may increase the risk of severe COVID-19 and lung fibrosis by disrupting the function of a previously unknown protein, says a new study. Read more here 👉️ edin.ac/4gw6ynT @simonbiddie.bsky.social, @centenaryinstitute.bsky.social @sydney.edu.au

Congratulations to Professor Andrew Jackson who has been awarded a 2.5 million euros @erc.europa.eu Advanced Grant to study the 'Mechanisms of Epigenetic Ageing and Sizing' #ERCAdG Read more 👉 edin.ac/4uMJULv @cmvm-edinburghuni.bsky.social

A new study has advanced understanding of the processes and factors required for the formation of a blastocyst - a ball of cells that forms in early pregnancy. Read more here 👉 edin.ac/44iT4V8

Study makes advances in reproductive biology | Institute of Genetics and Cancer | Institute of Genetics and Cancer

A new study has advanced understanding of the processes and factors required for the formation of a blastocyst - a ball of cells that forms in early pregnancy.

edin.ac

Filip Stefaniak, a Senior Researcher in the Bioinformatics and Protein Engineering Laboratory at @iimcb.bsky.social, undertook a research stay in Kathryn Ball’s lab at IGC. The visit was organised as part of the study visit programme of the #RACE_HorizonEU project. Read more here 👉 edin.ac/3Quhqbd

Only a week to go until the @edinburgh-uni.bsky.social's Three Minute Thesis Competition Final where nine finalists from the three Colleges will compete to deliver the best research presentation in just three minutes and with one slide. Find out more and reserve your ticket here 👉 edin.ac/3UKlYIR

We recently celebrated our research at an IGC Science Away Day with a wide range of presentations and flash talks. In addition, there were nearly 60 scientific posters on display throughout the day - congratulations to our three winners Anna Maria Ochocka-Fox, Alexis Ioannou and Alexandra Lesayova.

People living with hypermobile disorders face diagnostic delays of up to 2 decades, fragmented healthcare, and major impacts on education, employment and mental health, according to the largest study of its kind. Read more 👉 edin.ac/445Jzsq @cmvm-edinburghuni.bsky.social @ehlersdanlos.bsky.social

Study reveals two-decade delay in hypermobility diagnoses | Institute of Genetics and Cancer | Institute of Genetics and Cancer

People living with hypermobile disorders in the UK face diagnostic delays of up to two decades, fragmented healthcare, and major impacts on education, employment and mental health, according to the la...

edin.ac

This study by Kathryn Berg and Dervil Dockrell has highlighted the challenges facing people living with hypermobile disorders in the UK. @cmvm-edinburghuni.bsky.social @edinburgh-uni.bsky.social

The Guardian@theguardian.com · 2mo ago

UK hypermobility sufferers wait up to 21 years for diagnosis, study suggests

Register for the PRIME International Symposium to explore emerging ME/CFS research with researchers, clinicians, charities and people with lived experience. 🗓️ 28 Sept 9am-29 Sept 2pm Find out more and register here 👇 www.actionforme.org.uk/register-for...

At the start of Diabetes Week, Professor Helen Colhoun talks about her research into diabetes and the complications of the condition, using large data sets to understand trends, test the effectiveness & safety of new drugs and inform policy. Watch here: edin.ac/49NmWwb @diabetesuk.bsky.social

IGC Research in a Nutshell Professor Helen Colhoun

Professor Helen Colhoun Institute of Genetics and Cancer.

edin.ac

📢 The recording from the second PRIME research webinar is now available on our YouTube channel! 🔗 Watch the recording here: www.youtube.com/watch?v=NMlM...

Pat Brogan is a patient on the EMITT-1 trial which has found that using a new drug in conjunction with immunotherapy can shrink tumours by at least 30% or keep them stable in people with six different advanced and hard-to-treat cancers. Read more 👉 edin.ac/436rWIH @cmvm-edinburghuni.bsky.social

New drug shows efficacy for multiple cancers in clinical trial | Institute of Genetics and Cancer | Institute of Genetics and Cancer

Early results from a global clinical trial show that using a new pill with immunotherapy can shrink tumours by at least 30% or keep them stable in people with six different advanced and hard-to-treat ...

edin.ac

A trial involving IGC researchers Karen Taylor and @peterhall001.bsky.social has found many people with breast cancer can safely avoid chemotherapy with the use of a gene test, potentially sparing them unnecessary side effects without increasing the risk of the cancer returning. edin.ac/3PyrRKH

Gene test can safely spare many breast cancer patients of chemotherapy | Institute of Genetics and Cancer | Institute of Genetics and Cancer

Many people with breast cancer can safely avoid chemotherapy with the use of a gene test, potentially sparing them unnecessary side effects without increasing the risk of the cancer returning, a large...

edin.ac

Congratulations to @edinnovations.bsky.social Entrepreneur-in-Residence Jeff Wright who won the Impact Enabler award at @edinburgh-uni.bsky.social's Impact Festival for his work on the Viking Genes project, led by Jim Wilson, which received significant funding from our MRC Human Genetics Unit.

On World Blood Cancer Day, we're sharing this video by @anetamikulasova.bsky.social, talking about her research into Multiple Myeloma - one of three types of blood cancer. Watch here 👉 edin.ac/4wS0CeC Find out how to support her research here 👉 edin.ac/4dJOdkk @cmvm-edinburghuni.bsky.social

IGC Research in a Nutshell Dr Aneta Mikulasova. (Epi)genomic Instability in Multiple Myeloma.

IGC Research in a Nutshell. Dr Aneta Mikulasova.Institute of Genetics and Cancer, The University of Edinburgh.(Epi)genomic Instability in Multiple Myeloma.

edin.ac

Cell therapy for liver disease shows long-term benefits 💉 The 4 year follow up of the groundbreaking MATCH clinical trial, led by Professor Stuart Forbes, shows long-term benefits of macrophage cell therapy in patients regeneration-repair.ed.ac.uk/cell-therapy...

Cell therapy for liver disease shows long-term benefits | Institute for Regeneration and Repair | Institute for Regeneration and Repair

The 4 year follow up of the MATCH clinical trial shows long-term benefits of macrophage cell therapy in patients

regeneration-repair.ed.ac.uk

New publication: A unifying model of stem cell dynamics explains age-related methylation patterns across mammals @uoe-igc.bsky.social @edinburghbiology.bsky.social www.nature.com/articles/s43...

A unifying model of stem cell dynamics explains age-related methylation patterns across mammals - Nature Aging

A parsimonious model of stem cell dynamics describes how DNA methylation changes arise and propagate with age, unifying diverse epigenetic aging patterns and suggesting that stem cell dynamics are a k...

nature.com