UW–Madison Department of Biochemistry

@uwbiochem.bsky.social

Official Bluesky account of the world-renowned biochemistry research & teaching department at UW–Madison.

What can a microscopic organism in Lake Mendota teach us about cellular adaptation? The @cellraiser.bsky.social Lab is studying P. collini, a single-celled predator that reshapes its feeding structures to match changing conditions in its environment. Read the story: biochem.wisc.edu/2026/07/16/i...

Investigating a Microscopic Predator in Madison’s Lakes

Researchers in the Coyle Lab have identified unusual growth patterns and their underlying biochemical mechanisms in a single-celled organism on the hunt.

biochem.wisc.edu

Congratulations to IPiB graduate students Matthew Kim, Corinne Moss, and Fong Ning Liew, who earlier this month were presented Denton Awards for Graduate Student Excellence in Teaching and Mentoring and the Sigrid Leirmo Memorial Award in Biochemistry! ipib.wisc.edu/2026/07/06/t...

Three IPiB Grad Students Honored for Exceptional Mentorship and Teaching

Matthew Kim (Chaudhari Lab), Corinne Moss (Coon Lab), and Fong Ning Liew (B. Fox Lab) received awards at the IPiB summer reception.

ipib.wisc.edu

Kaitlyn continues to break barriers with her innovations for using LEA proteins to solve another major cryo-EM sample prep issue! This work should be of great interest to friends who are struggling with particle orientation bias. Another funtastic Lim X Grant collaboration! @uwbiochem.bsky.social

Kaitlyn Abe@kaitlynabe.bsky.social · 3w ago

1/5: Our latest preprint is out! We show that LEA proteins can diversify particle orientations in cryo-EM, helping to overcome preferred orientation at the air-water interface (AWI). www.biorxiv.org/cgi/content/... with @cijilim.bsky.social and Tim Grant #CryoEM #LEAproteins

@zjmaggiexu.bsky.social's story on suctorian trap structure adaptation is now online in @currentbiology.bsky.social , with new evolutionary analyses and modeling! This fall, Maggie will keep exploring predatory protists as a PD in @nbellono.bsky.social group; keep an eye out for her she's amazing!

sciencedirect.com

Scott Coyle@cellraiser.bsky.social · 9mo ago

How do cells adapt morphology to function? In a 🔥 preprint by @zjmaggiexu.bsky.social , with @dudinlab.bsky.social and @amyweeks.bsky.social , we identify a self-organizing single-cell morphology circuit that optimizes the feeding trap structure of the suctorian P. collini. 🧵 tinyurl.com/4k8nv926

Now online @pnas.org: We developed a simple, scalable, and accessible platform for deep profiling of phosphoeraser specificity using human phosphoproteome-derived peptide libraries (PhosPropels!) 🧪👩‍🔬https://www.pnas.org/doi/10.1073/pnas.2523183123

Phosphoproteome-derived peptide libraries for deep specificity profiling of phosphatases and phospholyases | PNAS

Protein phosphorylation is dynamically regulated by the opposing activities of phosphowriter enzymes (kinases) and phosphoeraser enzymes (phosphata...

pnas.org

Thanks to the Ono Pharma Foundation and The University of Chicago for supporting this amazing symposium! And congratulations to the Weeks lab's own Sopo Jalalishvili for winning a poster prize for her work on phospholyases! 👩‍🔬🧪@uwbiochem.bsky.social

ONO PHARMA FOUNDATION@onoinitiative.bsky.social · 2mo ago

Great momentum at 2026 Chicago Chemical Biology and Therapeutics Symposium, hosted by CCBT at The University of Chicago and Ono Pharma Foundation. Insightful presentations and meaningful interactions drove the success of the meeting. Grateful to all attendees! ccbt.bsd.uchicago.edu/events/

Congratulations to 52 exceptional biochemistry students recognized with scholarships, fellowships, and research support this spring! Their achievements are made possible in part by the generosity of donors and strong support from department and campus partners. biochem.wisc.edu/2026/06/01/b...

Biochemistry Department, Campus Recognize 52 Students with Scholarships, Fellowships, and Support in Spring 2026

The annual reception celebrated outstanding undergraduate and graduate biochemistry students.

biochem.wisc.edu

In the W-S lab's first preprint, we describe how genomic language models know something about RNA thermodynamics. Though we think this is cool, things get tricky! A growing practice for interpreting LMs is to perturb input tokens, often called "Categorical Jacobian": 👇

Bild

UW–Madison researchers are envisioning what local foods and green fuels could look like in a Jetsons-esque future. One question they’re asking: can photosynthetic organisms be grown using lunar or Martian soils? biochem.wisc.edu/2026/05/13/c...

Can We Grow Food in Extraterrestrial Soil?

The Gisriel Lab is exploring whether lunar and Martian soils can support cyanobacteria that are used as food and fuel additives.

biochem.wisc.edu

Join us for James Corban's Ph.D. thesis defense on May 26! His research in the Raman Lab developed methods to identify and characterize proteins associated with epigenetic shifts in mammalian cells. Learn more: ipib.wisc.edu/2026/05/08/i...

IPiB Thesis Defense May 26, 2026: James Corban

His research in the Raman Lab developed research methods to identify and characterize proteins associated with epigenetic shifts in mammalian cells.

ipib.wisc.edu

Congratulations to John Ralph, biochemistry emeritus professor, who has been elected to the National Academy of Sciences! Ralph and his lab studied lignin structure and biosynthesis, decoding lignin biochemistry and identifying biosynthesis pathways. Learn more: biochem.wisc.edu/2026/05/08/e...

Emeritus Professor John Ralph is Elected to the National Academy of Sciences

Members are recognized for their distinguished achievements in original research. Ralph is internationally recognized for his work on lignin.

biochem.wisc.edu