Wonderful meeting @aegeanstemcells.bsky.social! An incredible lineup of speakers and spectacular science. Thanks to our own Jeff @epigeneticsmsn.bsky.social for organizing this event. What could be better than having @uwmadscience.bsky.social CRB delegation in sunny Crete? @blanclab.bsky.social
Valentina Lo Sardo
@valels.bsky.social
Assistant Professor at University of Wisconsin-Madison SMPH, Cell and Regenerative Biology Department. Stem cell-based functional genomics of cardiovascular disease. Opinions are my own.
Thanks to the UW-Madison Stem Cell and Regenerative Medicine Center for highlighting our recent work!!🫀🧫🔬 stemcells.wisc.edu/2025/06/04/u...
UW–Madison researchers find hidden clues in a decades-old mystery surrounding cardiovascular disease
Researchers at the University of Wisconsin–Madison have uncovered new evidence in a decades-old genetic mystery, discovering how multiple genetic variations in a long-mysterious region of the human ge...
stemcells.wisc.edu
If you are passionate about stem cells consider coming to Greece for a wonderful lineup of speakers, a lot of networking and amazing science!! Check the website for early registration and travel awards!
🔬 6th International Aegean Conference on Stem Cells 📢 Join us Oct 1–6, 2025 in Crete, for talks on stem cell biology, regenerative medicine, genome editing & aging. 📅 Abstracts & Early Reg: Due June 1, 2025 🔗 Register now: www.aegeanconferences.org/src/App/conf... #AegeanStemCells2025 #StemCells
CXCL12 drives natural variation in coronary artery anatomy across diverse populations: Cell www.cell.com/cell/fulltex...
CXCL12 drives natural variation in coronary artery anatomy across diverse populations
Coronary dominance is a clinically important developmental phenotype that dictates whether the left or right coronary arteries perfuse the back of the heart. Genome-wide association studies and downst...
cell.com
Thrilled to share the🥇paper from the lab @ahajournals.bsky.social. Here we continue to unravel the mysteries of the 9p21.3 CAD locus showing it drives VSMC transition into an osteochondrogenic state, promoting calcification. @clintomics.bsky.social @UWMadison CRB. www.ahajournals.org/doi/10.1161/...
9p21.3 Coronary Artery Disease Risk Locus Drives Vascular Smooth Muscle Cells to an Osteochondrogenic State | Arteriosclerosis, Thrombosis, and Vascular Biology
BACKGROUND: Genome-wide association studies have identified common genetic variants at ≈300 human genomic loci linked to coronary artery disease susceptibility. Among these genomic regions, the most i...
ahajournals.org
Congrats to @andreagalmozzi.bsky.social lab for this great study just out in @natmetabolism.bsky.social!! I’m a proud colleague, partner and wife!! ❤️❤️❤️
Proud to share the work of my forst ever PhD student and first author of this paper @dylanduerre.bsky.social!! Here, he summarizes it perfectly! #brownfat #metabolism #BCAA #heme @uwmadison.bsky.social @uofutahcihd.bsky.social
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...
A new large language of life model (LLLM) for the transcriptome that predicts gene expression within and across human cell types www.nature.com/articles/s41... @nature.com For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...
A foundation model of transcription across human cell types - Nature
A foundation model learns transcriptional regulatory syntax from chromatin accessibility and sequence data across a range of cell types to predict gene expression and transcription factor interactions...
nature.com
🤩❤️ Beautiful atlas of vascular cells in the human body! www.nature.com/articles/s41...
An organotypic atlas of human vascular cells - Nature Medicine
A vascular cell atlas integrating single-cell data of 19 organs and tissues from 62 donors identifies angiotypic and organotypic characteristics of endothelial and mural cells.
nature.com