In their Cell Science at a Glance article and the accompanying poster, @ritoghose.bsky.social and @vickysanzmoreno.bsky.social @icr.ac.uk discuss the defining features of amoeboid cancer cells and highlight their therapeutic vulnerabilities. #OpenAccess journals.biologists.com/jcs/article/...

Very happy to share our latest work spearheaded by Jaume Barcelo.Thanks to collaborators @icr.ac.uk @breastcancernow.bsky.social @bartscharity.bsky.social CRUK Pan-cancer analysis reveals Rho kinase addiction as a vulnerability of de-differentiated cancer cells: iScience www.cell.com/iscience/ful...

Pan-cancer analysis reveals Rho kinase addiction as a vulnerability of de-differentiated cancer cells

Therapeutics; cancer; transcriptomics

cell.com

Delighted to share our latest views on our favourite cancer cells Well done @ritoghose.bsky.social 👏 @icr.ac.uk @breastcancernow.bsky.social Amoeboid cancer cells at a glance journals.biologists.com/jcs/article/...

Amoeboid cancer cells at a glance

Summary: Amoeboid cancer cells exploit actomyosin contractility, metabolic adaptability and immune evasion to drive metastasis, representing a distinct and therapeutically targetable state within the ...

journals.biologists.com

It is sad to say goodbye to one of our most valued lab members. Samantha George we wish you the best of luck in your future endeavours. We will miss you very much 😍 @icr.ac.uk

We are very happy to welcome Yifei Zhang, as a new lab member to the Cytoskeleton and Metastasis Team. Yifei will be studying transcriptional and cytoskeletal dynamics in invasive lobular carcinoma (ILC). @icr.ac.uk

Delighted to have been elected a Fellow of the European Academy of Cancer Sciences alongside some outstanding colleagues! www.europeancanceracademy.eu/news/new-eac...

Applications now open for CRUK Clinical Academic PhD Training Programme. Join us @icr.ac.uk and The Royal Marsden NHS Foundation Trust. We are offering a super exciting project to investigate cytoskeletal dynamics in Circulating Tumour Cells from Breast Cancer Patients.

Heads up! Small change to Friday’s workshop: Dr. Sebastian Carotta can’t make it, but we’re thrilled to have Dr. Victoria Sanz-Moreno (ICR) stepping in to talk about “Biomechanical hallmarks & vulnerabilities of metastatic & therapy resistant cancer cells” See you there! @vickysanzmoreno.bsky.social

Adaptmet@adaptmet.bsky.social · 9mo ago

📢Frontiers in Metastasis Research Workshop! 🗓️ 14 NOV 2025 (9:00–12:30) in Barcelona. Intensive session on metastatic adaptation, therapeutic resistance, and TME. Open event. Full Agenda & Reg: irbbarcelona.org/adaptmet-workshop #CancerResearch #Metastasis #TME #Oncology

Sad to see three of our beloved lab members leaving us! Yumiko Teigen, Paramita Kundu and Jaume Barcelo- We wish you the best of luck for your future endeavours! @icr.ac.uk

Early stages of #metastasis are poorly understood despite causing 90% of cancer deaths. A new project led by Prof Darryl Overby and Prof @vickysanzmoreno.bsky.social is looking to develop tools to study #cancer spread in unprecedented detail while reducing the need for animals in research.🐁👇

CRUK Convergence Science Centre@crukconvergence.bsky.social · 10mo ago

Congratulations to our 2025 Development Fund awardees! 🎉 From new detection tools to targeted nanotech therapies, these seed funded projects explore bold ideas to improve cancer diagnosis & treatment. 👉 bit.ly/4gV38tf @icr.ac.uk @imperialcollegeldn.bsky.social @imperialsandc.bsky.social

We are offering a super exciting project to develop new ways of targeting metastatic cancer cells! Amazing supervisory team: Primary supervisor: Professor Joanna Loizou Associate supervisor: Professor Zoran Rankovic Secondary supervisor: Professor Victoria Sanz-Moreno @icr.ac.uk

Targeting AMPK as a metabolic vulnerability of metastatic cancer cells

Targeting AMPK as a metabolic vulnerability of metastatic cancer cells

icr.ac.uk

We are so happy to welcome @dorioliveri.bsky.social as a new lab member to the Cytoskeleton and Metastasis Team. Doriana will study how the extracellular matrix in different metastatic sites regulates tumour-immune cell interactions😀 ADAPTMET @icr.ac.uk @breastcancernow.bsky.social

The stage is set! @vickysanzmoreno.bsky.social is kicking off their keynote at #cellmech2025.

CellMech2025!! Exciting!

Congratulations to Yumiko Teigen who had her PhD viva yesterday! She did such a fantastic job! Thanks to the examiners for their insightful comments @cancerresearchuk.org @breastcancernow.bsky.social @icr.ac.uk @qmbci.bsky.social 😍

Really exciting to see these results from our Curestarter researchers - thanks for sharing @vickysanzmoreno.bsky.social!

VickySanzMoreno@vickysanzmoreno.bsky.social · last yr.

🚨 New publication alert! Excited to share our latest work SLC7A11 protects amoeboid-disseminating cancer cells from oxidative stress: Cell Reports www.cell.com/cell-reports...

Congratulations to Samantha George in the lab for receiving the Best Talk Prize at "The Diversity in Immunology Meeting" by @britsocimm.bsky.social for her beautiful work on tumour-associated macrophages. We are very proud of you Sam! 🤩

🚨 New publication alert! Excited to share our latest work SLC7A11 protects amoeboid-disseminating cancer cells from oxidative stress: Cell Reports www.cell.com/cell-reports...

SLC7A11 protects amoeboid-disseminating cancer cells from oxidative stress

Graziani et al. show that SLC7A11 increases during melanoma disease progression. SLC7A11 promotes Myosin II-driven amoeboid invasive behavior while shielding amoeboid cancer cells from oxidative stres...

cell.com

The results, published in @cp-cellreports.bsky.social could lead to new tests to spot the most aggressive cancers, and treatments to stop them spreading. “If we take away the melanoma cells’ shield and armour, we could stop cancer in its tracks.’ - Lead researcher Prof @vickysanzmoreno.bsky.social

BREAKING 📰 A ‘suit of armour’ protein could be targeted to stop aggressive #Melanoma from spreading. ICR scientists have discovered that SLC7A11 protects the most aggressive melanoma cancer cells from damage as they pass through stressful environments. More here ⤵️ www.icr.ac.uk/about-us/icr...

I am happy to be shortlisted in the Life Sciences category of the #GlobalCall25. This recognition brings me a step closer to the Science Breakthroughs of the Year, to be celebrated at the #FallingWalls #ScienceSummit25 from 6-9 November. More info: falling-walls.com/science-summ... @FallingWalls

A huge thank you to all the amazing delegates who joined us for Small G Proteins in Cellular Signalling and Disease 2025 this week! We hope you enjoyed the conference and look forward to seeing you at the next one. #BiochemEvent #SGP25 🧪

Last day of the #SmallGproteins meeting, great evening last night meeting researchers in the field hearing about people’s journeys, and gave advice on expressing a phosphorylated GTPase. Looking forward to Session 6 kicked off by @vickysanzmoreno.bsky.social! @biochemsoc.bsky.social #BiochemEvent

Excited to be selected as one of the Social Media Contributors at the #BiochemEvent Small G Proteins Meeting next week, thanks to @biochemsoc.bsky.social. I look forward to hearing about and discussing the latest research in the area as well as presenting my own PhD work about Arf proteins!

The Company of Biologists Workshop - Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism Thank you to Workshop organisers Marco Foiani, Ana-Maria Lennon-Duménil, Victoria Sanz-Moreno and Giorgio Scita. #Workshop #Biology #CellBiology #Community #Collaboration #Research

We are delighted to host @vickysanzmoreno.bsky.social today from the @icr.ac.uk! "Biomechanical hallmarks and vulnerabilities of metastatic cancer cells" 📍 Alfred Denny Conference Room 📅 4th June - 1pm @insigneoinstitute.bsky.social @sheffielduni.bsky.social @sheffielduni.bsky.social

Very proud of former PhD student Yaiza Jung who has received the #BACR Chris Marshall Prize for Cell Signalling 😍! it was such a pleasure to co-supervise her PhD with @jezcarlton.bsky.social 😀

Immunotherapy can help people with advanced head and neck cancer live years longer without their disease growing or coming back. It's the biggest improvement in treating this cancer type for decades. Find out more: news.cancerresearchuk.org/2025/05/31/asc

ASCO 2025: head and neck cancer immunotherapy and targeted drugs for breast cancer improve outcomes - Cancer Research UK - Cancer News

Our experts are helping us sort through the cancer studies at ASCO, the world's biggest cancer conference.

news.cancerresearchuk.org

BREAKING 📰 A powerful new drug for advanced #BreastCancer can be used to treat emerging tumours, months before they have a chance to grow, keeping patients well for longer, according to new research shared today at @ascocancer.bsky.social Professor Nick Turner shares his findings ⬇️ #ASCO25

Paper accepted! what a great group of people I get to work with every day! 🤩 Celebrating good news is so important! 👇