Tori Hall

@victoriahall.bsky.social

I couldn’t have asked for a better partner than Dr. Victoria Hall who co-led this work with me. Thanks to the Ajmera Transplant Centre and PSI Foundation for their funding support, to Dr. Lavoie & his team, our UHN colleagues, and to the participants whose generosity made this work possible.

Two patients with refractory myeloma who had excellent antitumor responses to cilta-cel CAR T-cell therapy later had T-cell lymphomas that contained the lentivirus construct used to generate the CAR T-cell product. Brief Report on the CARTITUDE-4 trial: nej.md/4gA6G27 #MedSky #Hematology

CAR+ T-Cell Lymphoma after Cilta-cel Therapy for Relapsed or Refractory Myeloma | NEJM

We describe two patients in whom malignant monoclonal T-cell lymphoproliferation developed after administration of chimeric antigen receptor (CAR) T-cell therapy with ciltacabtagene autoleucel (cil...

nej.md