WGDip

@wgdip.bsky.social

Reappraising the role of whole genome duplication and rediploidisation in eukaryotic evolution. Funded by BBSRC Strategic Longer and Larger scheme. Check out our website for information about the project, team and more! https://www.rediploidisation.org/

Thanks @luohaoxu.bsky.social for presenting at #WGDip’s science forum. Using snow carp as a model, he argued that chromosome fusions often initiate rediploidisation after autopolyploidy. Featuring a haplotype-resolved assembly with 443 chromosomes (20n!) & insights into polyploid sex determination.

Diagram summarising key elements of Professor Luohao’s talk that was based on his recent publication in Nature: "Chromosomal fusions trigger rediploidization of autopolyploid genomes". 


1. Trio Construction.  The parent–offspring trio of S. younghusbandi.
Autopolyploid genome assembly. 

2. Hi-C heatmap of S. younghusbandi, with homologous chromosomes involved in fusions placed at the end.

3. Unbalanced chromosome fusion. Showing fusion Chr19-Chr22, Chr15-Chr4, Chr16-Chr8, Chr23-Chr20, Chr11-Chr14 in S. younghusbandi.

4. Meiosis pairing. Fluorescence in situ hybridization of centromeres and telomeres on meiotic metaphase I chromosomes displaying examples of a bivalent ring, a bivalent chain and a tetravalent ring

5. Asynchronous rediploidization. Timeline demonstrating the gradual shift from a tetraploid state to a diploid state. The timeline shows a decrease from 4n=100 to 4n=90 over 30mya in S. younghusbandi.

Huge congratulations to #WGDip project partner Aoife McLysaght for receiving the Community Service Award from @official-smbe.bsky.social. This recognises Aoife’s outstanding contributions and commitment to building stronger research communities through collaboration, leadership, and generosity. 👏

Aoife McLysaght receiving a Community Service Award from current SMBE president Juliette de Meaux on the main stage at SMBE 2026

The #WGDip team really enjoyed #SMBE2026! We shared posters from Zoe Vance, Anthony Redmond and Lucas Freitas, plus flash talks from Róisín Long and Lukasz Niezabitowski. Great to see growing interest in rediploidisation with lots of interesting chats! Thanks to the organisers for an epic meeting! 👏

🌊Happy #WorldOceanDay! 🌊 Today we reflect on one of the smallest 🔬 eukaryotes studied by #WGDip, diatoms! These tiny single-celled, photosynthetic algae found across aquatic environments play an outsized role in our planet's health...

Photomicrograph of fifty species of diatoms arranged within a circular shape. Photograph by Randolph Femmer is public domain from USGS Library of Images From Life. 

LINK: https://www.usgs.gov/media/images/diatoms-50-species

#WGDip hosted @ferdix.bsky.social (University College London) who reviewed the emergence of chaetognaths & priapulids. Discussing gene duplication, cryptic WGD, the impact of gene loss & maintenance or dispersion of ancestral bilaterian linkage groups & the emergence of new cell types & morphologies

Happy #BiologicalDiversityDay! 🌍🌿🐟🐌 #WGDip explores how WGD & rediploidisation have shaped eukaryotic diversity through evolutionary time. By studying genomes from a wide range of organisms, we aim to understand how these processes contributed to the extraordinary diversity of life we see today!

8 images of a variety of animals. Photo credits below.

Sockeye Salmon - Photo by Katherine Panfilova https://creativecommons.org/licenses/by-nc/4.0/
https://www.inaturalist.org/observations/317865493

Tea - Photo by Bart Wursten https://creativecommons.org/licenses/by-nc/4.0/
https://www.inaturalist.org/observations/242353488

Kelp Lace Bryozoan - Photo by Zach Berghorst
https://creativecommons.org/licenses/by-nc/4.0/
https://www.inaturalist.org/observations/109715280

Apple - Photo by Michal Svit 
https://creativecommons.org/licenses/by-nc/4.0/
https://www.inaturalist.org/observations/266777224

Angiosperms have a complex evolutionary history shaped by WGD, with different plant groups experiencing these events at different times & frequencies! #WGDip is looking at the Maleae tribe. This fascinating group includes familiar favourites like apples, pears & quinces 🍏🍐🍎

#WGDip is exploring the genomic history of species across the eukaryotic tree of life. This includes the flowering plant order Ericales - an incredibly diverse lineage with over 12,000 species! Chances are, you already know (and love) some of its members… like tea, kiwi, and blueberries! 🍵🥝🫐

Congrats to @luohaoxu.bsky.social & team for revealing the role of chromosome fusions in initiating asynchronous rediploidisation in autotetraploid snow carp. Featuring #WGDip lead Dan Macqueen as co-author. A landmark study in our ongoing understanding of rediploidisation! @nature.com @ukri.org 🧪

@luohaoxu.bsky.social · 3mo ago

Thrilled to share our recent publication in @nature.com. We discovered that snow carps experienced a relatively recent whole genome duplication #WGD, making this lineage an ideal lineage to study #rediploidization. www.nature.com/articles/s41...

Today we celebrate #NationalDNADay and reflect on how far genomic science has come, from discovering the structure of DNA🧬 to the completion of the Human Genome Project🌐. Without these insights, modern evolutionary genomics projects like #WGDip wouldn’t be possible! 🧪

Happy #worldbookday!📚 #WGDip was inspired by Susumu Ohno’s "Evolution by gene duplication”, published 56 years ago, before the modern era of genomics. His book argued for the central importance of duplicating both individual genes & whole genomes as 'fuel' for great leaps in biological evolution...

Image of the book "Evolution by gene duplication” by  Susumu Ohno.

Happy #EarthDay! 🌍 As evolutionary biology researchers, we’re reminded every day that the diversity of life on Earth is the result of millions of years of evolution, adaptation, & resilience. Today we acknowledge the importance of protecting the natural world that makes this research possible! 🐌🐟🌱

Can you identify this unusual purple-flowered plant in bloom at the @thebotanics.bsky.social?🔎🪻 This plant has no leaves & cannot photosynthesise. It's an important early spring flower, especially for bees🐝. Its nectar is high in ammonia, making it unsavoury for other pollinators & nectar robbers.

Image of Lathraea clandestina (Purple Toothwort). A small purple plant with no leaves. Image of Lathraea clandestina (Purple Toothwort). A large cluster of small purple plants with no leaves at the base of a tree.

🌳🌲Today we celebrate #InternationalForestDay & their incredible diversity!🌲🌳 Willows (Salicaceae) are a remarkable family - with a well-documented ancestral WGD event - that includes trees with huge value for people & the planet. For centuries, willows have been used in basket weaving🧺, ...

🧪A recent article in Science Advances revisits long-debated WGD events during early seed plant evolution. Using dosage-sensitive genes as markers of WGD, the authors found little support for an angiosperm-specific WGD, and strong evidence for a single WGD shared by all seed plants. buff.ly/W0hQYno

Revisiting ancient whole-genome duplications in the seed and flowering plants through the lens of dosage-sensitive genes

Dosage-sensitive genes suggest no ancestral angiosperm WGD.

buff.ly