Meet @winchesterl.bsky.social an Oxford Associate Professor shaping dementia research with integrative genomics, proteomics, and ML. From biomarkers to therapeutic insights, her work spans multi-omics, biobanks, and real-world data 🧠🔬 www.dementiaresearcher.nihr.ac.uk/profile-dr-l...

Profile – Dr Laura Winchester, University of Oxford - DEMENTIA RESEARCHER

Dr Laura Winchester is an Oxford Associate Professor using genomics, proteomics and machine learning to uncover disease mechanisms and biomarkers in dementia.

dementiaresearcher.nihr.ac.uk

🧠📊 Join us for the JUNE DEMON Biomarkers Working Group 📅 10 June 2026⏰ 10:00–11:00 BST Online. We're pleased to host Dr Henry Musto presenting "Survival-Based AI for Dementia Prognosis Prediction". Please message for joining details. #academicsky #dementiaresearcher

Our latest preprint is out and we found that sugar derivatives are increased in Alzheimer's Disease & identified a pathway that could be modulated www.medrxiv.org/content/10.6...

Polyol pathway dysregulation in CSF links glucose metabolism to tau pathology inde-pendently of amyloid and genetic predisposition

Dementia affects approximately 60 million people worldwide, yet molecular mechanisms linking early neuropathological changes to clinical progression remain poorly understood. We performed targeted and...

medrxiv.org

New preprint using the Biohermes cohort to explore amyloid protein signatures. #proteomics

bioRxivpreprint@biorxivpreprint.bsky.social · 3mo ago

Proteomic Signatures of Neuropathological Alterations in Alzheimer's Disease: Insights from the Bio-Hermes Study https://www.biorxiv.org/content/10.64898/2026.05.20.726478v1

Stumbled across the Luminarium with my daughter for a sunday afternoon lesson in visual light. #architectsofair @harwellcampus

Brilliant work from @joshuasammet.bsky.social and so pleased to see his hard work in print

Joshua Sammet@joshuasammet.bsky.social · 3mo ago

Been a while since acceptance, but I am incredibly excited to share that my first paper has been published 🎉 www.sciencedirect.com/science/arti... Big thanks to @winchesterl.bsky.social for her continuous supervision and support over years of work.

Calling for your paper for the upcoming collection Brain metabolomics in dementia and neurological disease I’m honoured to be serving as the collection’s Guest Editor and eager to read your submission. #CallForPapers @natureportfolio.nature.com Learn more about the collection: go.nature.com/41S5bI3

Brain metabolomics in dementia and neurological disease

This Collection invites original research using metabolomic platforms to explore the mechanisms of dementia and neurological disease or aid in its diagnosis ...

go.nature.com

January @DEMONNetworkUK Biomarkers working group is hosting an Inflammation special with Dr Maura Malpetti and Dr Sofia Michopoulou “Unravelling Inflammation in Dementia: Proteomic and Imaging Insights” 📅 Wed 14th Jan 10.30am GMT. New members welcome - pls message for details.

Trying to finish a grant submission while child plays the Imperial March on the kazoo. I hate inset days and also Santa for gifting kazoos this year.

Happy New Year everyone! 🚨Join our first @DEMONNetworkUK #Genetics #Omics meeting of 2026 - THURSDAY 8th January at 2.30 PM (UK Time). Delighted to have Juan Botia as invited speaker – “Using graph neural networks to expand what we know about neurodegeneration” Join the network or DM for more info

Giant lazer celebrations from the diamond light source for new year. #thebeam

Post Christmas work message but finally got our longitudinal proteomics study of Parkinson's subtypes into preprint this month. Dedicated mechanistic modules for 🧠+🩸using the Tracking Parkinson's and GNPC cohorts #parkinsons #academicSky #proteomics www.biorxiv.org/content/10.1...

Longitudinal Proteomic Profiling Defines Robust Molecular Subtypes Underlying the Heterogeneity of Parkinson’s Disease

Heterogeneity of Parkinson’s disease (PD) pathology is a barrier to developing therapeutics and understanding progression and prognosis. High throughput proteomic measures can be used to better interp...

biorxiv.org

Good news at last. www.ctvnews.ca/health/artic...

Study finds potential link between high-fat cheese and lower risk of dementia

A study out of Sweden has looked at the possible link between eating more high-fat cheese, like cheddar, gouda and brie, and a lower risk of developing dementia.

ctvnews.ca

There is still time to register for today Fluid and Neuroimaging Biomarker Forum discussion - todays chat will explore sample handling and data interpretation. 12pm GMT in the Dementia Researcher Community communities.dementiaresearcher.nihr.ac.uk/c/live-poste...

Fluid and Neuroimaging Biomaker Forum

Fluid and Neuroimaging Biomaker Forum

communities.dementiaresearcher.nihr.ac.uk

Joint DEMON network working group this month discussing female specific lipid expression in #Alzheimer’s. Please pm me or @saobettencourt.bsky.social for more details. #academicsky ⬇️

Conceicao Bettencourt@saobettencourt.bsky.social · 9mo ago

🚨Join our next @DEMONNetworkUK #Genetics and #Omics joint with #Biomarkers meeting on THURSDAY 6th November at 2.30 PM (UK Time). Delighted to have Asger Wretlind as invited speaker – “Unsaturated #Lipid Deficits: A #Female Specific #Alzheimer's Signature” Join the network or DM for more info!

Enjoying the skeleton hard at work in his lab in this year's local Halloween trail.

Last training run yesterday before the Oxford half on Sunday. Running for Alzheimer’s Research UK and still looking for sponsors. And please have a look at all the other ARUK researchers running this weekend. @arukthamesv.bsky.social www.justgiving.com/fundraising/...

This is an interesting one for potential reviewers. The authors used the NHANES cohort publications to count the copycats.

Margot Finn@eicathomefinn.bsky.social · 11mo ago

'In a preprint posted on medRxiv on 12 September1, researchers identified more than 400 such papers published in 112 journals over the past 4.5 years'. Link to preprint: www.medrxiv.org/content/10.1...

Big news! I loved researching and writing this book, which is all about shedding the shame, and getting really curious about urges to pick, pull and bite. I can't wait to share it with you! It's out on April 2nd, and is available to pre-order now. #bfrb #bfrbs #bodyfocusedrepetitivebehaviors

Enjoying this as a distraction this morning as well...

David Bauer@davidbauer.ch · 11mo ago

In the first seven days since I launched this new game, almost ten thousand people from 82 countries have played it. (Top cities so far: New York City, Zurich, Toronto, Chicago, Berlin, Vienna, Stockholm) What topics would you like me to add next? dataguessr.com

My moral support for responding to reviewers on a Saturday morning. He's fed up as well. #Caturday

Who’s ready for Manchester 2026? 🧠 AAIC Neuroscience Next is free, global, and packed with chances to present your work. Abstracts open 22 September – are you in? #AAICNeuro pod.fo/e/329e2b

Dementia Researcher: The Road To AAIC Neuroscience Next 2026

In this episode of the Dementia Researcher podcast, host Adam Smith discusses the upcoming AAIC Neuroscience Next Conference with guests Tricia Nicholson, Dr Amanda Heslgrave, and Kalli Mavr...

pod.fo

Starting the training runs for Oxford half from the beach this morning. Will be looking for sponsorship when I get home ... www.justgiving.com/team/aruk-ru...

AI slop and the destruction of knowledge irisvanrooijcogsci.com/2025/08/12/a...

AI slop and the destruction of knowledge

This week I was looking for info on what cognitive scientists mean when they speak of ‘domain-general’ cognition. I was curious, because the nuances are relevant for something I am researching at t…

irisvanrooijcogsci.com

Just came across this graphical abstract for a paper. No idea what they were going for with the whale and rainbow, but at least it is very calming

Big day for @neuroproteome.bsky.social All proteomic data released at neuroproteome.org and publications in print. Lots to read on AD, PD, FTD and ALS.

Nature Portfolio@natureportfolio.nature.com · last yr.

Analyses of one of the world’s largest protein datasets offer new insights into the biological underpinnings of major neurodegenerative diseases, according to research presented by the Global Neurodegeneration Proteomics Consortium (GNPC) in Nature Medicine and Nature Aging. #medsky 🧪

Looking for a new PhD student interested in Alzheimer’s disease and informatics starting in October. Details below.

Dementia Researcher@dementiaresearcher.bsky.social · last yr.

🎓 Join the University of Oxford for a fully funded DPhil in Psychiatry, studying neuroinflammatory pathways in dementia using big data and AI. Supervised by @winchesterl.bsky.social & Prof Alejo Nevado-Holgado - Apply by 25th July www.dementiaresearcher.nihr.ac.uk/job/phd-infl...

For the June DEMON Biomarker working group we are pleased to host Dr Ehsan Pishva who will be presenting his work on DNA methylation and environmental exposures in Parkinson’s disease. Wednesday 11th June 10am BST. Please message for joining links.

🚨Calling all ECRs working on dementia biomarkers! 🚨 Are you interested in helping us shape the scientific programme for a one-day conference in February 2026? Find out more & register your interest 👉 www.dementiaresearcher.nihr.ac.uk/help-design-...

Help Design a Pioneering Dementia Biomarkers Conference - DEMENTIA RESEARCHER

Are you an ECR working on dementia biomarkers? Help shape a major 2026 conference & UK AAIC hub bid. Volunteer by 11 May to get involved!

dementiaresearcher.nihr.ac.uk

My latest @newscientist.com cartoon