WredenbergLab
@wredenberglab.bsky.social
Mitochondrial research at the Division for Molecular Metabolism, Karolinska Institute wredenberglab.com
Why mammalian mitochondrial transcripts are polyadenylated is still not fully understood. So we wrote a review collecting our thoughts. www.sciencedirect.com/science/arti...
Mitochondrial RNA polyadenylation: Defining RNA fate through 3′ end regulation
Polyadenylation is a conserved post-transcriptional RNA modification with fundamentally different consequences for RNA fate across biological systems.…
sciencedirect.com
We report new pathogenic variants in the mitoribosome factor MRPS22. Thanks to all involved. academic.oup.com/hmg/article/...
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Interested in mitochondria and metabolism? We are hiring. Come join us in Stockholm. ki.varbi.com/what:job/job...
Postdoctoral studies in mitochondrial regulation of metabolism (scholarship)
Do you want to contribute to top quality medical research? The Wredenberg group at Karolinska Institutet is seeking a highly motivated postdoctoral researcher to investigate how mitochondrial function
ki.varbi.com
We are hiring! Come and join us in Stockholm to study mitochondrial metabolism. ki.varbi.com/what:job/job...
Postdoctoral researcher in mitochondrial biology (scholarship)
Do you want to contribute to improving human health? The Division of Molecular Metabolism at Karolinska Institutet is located in the newly built Biomedicum at the Solna campus. The division offers a h
ki.varbi.com
Excited to share our latest work on how mitochondrial methylation shapes gene expression. Using long-read RNAseq and cryo-EM, we uncover two methylation-dependent checkpoints in ribosome biogenesis. Thanks to everyone invovled. @ruthicglasgow.bsky.social @amunts.bsky.social 🔗 rdcu.be/etk12
The mitochondrial methylation potential gates mitoribosome assembly
Nature Communications - Here, using long-read RNA sequencing, SILAC proteomics, and cryo-EM, the authors show that loss of mitochondrial methylation impairs rRNA processing and ribosome maturation,...
rdcu.be
Hello fellow mitochondriacs! Are you passionate about mtDNA? We now offer a 2-year postdoc opportunity for studies of mtDNA instability and its signaling. Apply by May 18th to join our international team in exotic Umeå. Please share! www.umu.se/en/work-with...
Postdoctoral fellowship (2 years) to study mitochondrial DNA stability
umu.se
Happy to share out latest collaborative work with the groups of Ricarda Richter-Dennerlein and Peter Rehling just out in @natcomms.nature.com. Great work led by two very talented PhD students - Franziska Finke (our lab) and Marleen Heinrichs (Richter-Dennerlein lab). www.nature.com/articles/s41...
Coupling of ribosome biogenesis and translation initiation in human mitochondria - Nature Communications
Mitochondrial ribosome biogenesis requires the assistance of multiple assembly factors. Here, the authors provide insights into the essential role of the GTPase MTG3 during small subunit biogenesis an...
nature.com
New paper out from the Falkenberg and Gustafsson labs. Thanks to Pretzel for a successful collaboration. www.nature.com/articles/s41...
Small molecules restore mutant mitochondrial DNA polymerase activity - Nature
An activator of DNA polymerase γ restores function to disease-causing mutant variants and demonstrates a potential route to treatments for inherited mitochondrial disorders involving POLG mutations.
nature.com
Interested in mitochondrial biology? We are looking for an enthusiastic PostDoctoral fellow and PhD student to join our group in Stockholm. For the PhD position: kidoktorand.varbi.com/what:job/job... For the PostDoc position: ki.varbi.com/what:job/job...
Doktorandplats inom mitokondriell metabolism
Vill du bidra till medicinsk forskning av toppkvalitet? Att vara doktorand innebär att vara antagen till en utbildning på forskarnivå (forskarutbildning) där man följer en individuell studieplan.
kidoktorand.varbi.com
We are excited to share our latest work on mechanisms that protect from mitochondrial dysfunction. Thank you to all collaborators and the 4th anonymous reviewer for supporting us. @naturecomms.bsky.social www.nature.com/articles/s41...
Preventing excessive autophagy protects from the pathology of mtDNA mutations in Drosophila melanogaster - Nature Communications
Finding ways to compensate for mitochondrial dysfunction is essential. Here, the authors performed a genome-wide genetic screen to identify genes that mitigate the larvae lethal phenotype of a fruit f...
nature.com
We are hiring. Looking for a PostDoc in mitochondrial biology? We are offering an excellent scientific environment at the Division of Molecular Metabolism. Apply here: ki.varbi.com/ny/what:job/...
1-2 Postdoctoral researchers in mitochondrial biology (scholarship)
Do you want to contribute to improving human health? Research at the Division of Molecular Metabolism aims to understand the regulation of mitochondrial function and the role of mitochondrial dysfunct
ki.varbi.com