A special highlight of our work on precision fMRI of the prefrontal cortex

WCIA 3 News@wcia3news.bsky.social · 2w ago

Out of the 30 million MRIs performed in the United States every year, data shows about 22% of those are on the brain. Now, researchers at the University of Illinois are mapping out ways to see the results at a more detailed level.

Happy to share that our paper on objective quality assessment for "precision" fMRI is now out in @cp-neuron.bsky.social A recap of what it does, what's new since the preprint, and code you can run on your own data. cell.com/neuron/fullt...

How can we acquire new knowledge and skills on a daily basis while remaining the same person? I'm excited to share our new preprint led by @hyejinjadelee.bsky.social & Ally Dworetsky tackling this question, just in time for #OHBM2026: doi.org/10.64898/202... 🧵👇 #neuroskyence #PsychSciSky

Functional brain organization is stable within individuals across years

Brain regions exhibit dynamic yet highly coordinated activity patterns that form large-scale functional networks measurable through resting-state correlations. While their association with fluctuating...

doi.org

New preprint as my first post! "Monosynaptic connections link functionally similar regions in human cortex." We use electrical stimulation + fMRI in epilepsy patients to map whole-brain monosynaptic connectivity at 42 cortical sites. doi.org/10.64898/202... 1/n

If chains are a fundamental organizational principle of cortex, how have we never noticed them before? The answer is that we are used to looking at data averaged across large groups, and group averaging hides them!

Thanks to @beckmanillinois.bsky.social for a nice write up on our work: beckman.illinois.edu/news/article...

Beckman researchers map prefrontal cortex in individuals, reveal fine-scale structure with precision fMRI

beckman.illinois.edu

Caterina Gratton@caterinagratton.bsky.social · 3mo ago

Very excited about this project, led by @zachladwig.bsky.social We show that an individual’s lateral prefrontal cortex has reliable and highly detailed network organization missed in past group approaches. Full🧵 coming soon!

(1/5) Our paper is out now in Neuron! bsky.app/profile/cp-n... The LPFC has fine-scale organization that gets missed in group-averaged data because of inter-individual variability. It is visible in individuals in both resting-state and task data.

Neuron@cp-neuron.bsky.social · 3mo ago

Very excited about this project, led by @zachladwig.bsky.social We show that an individual’s lateral prefrontal cortex has reliable and highly detailed network organization missed in past group approaches. Full🧵 coming soon!

Neuron@cp-neuron.bsky.social · 3mo ago

Individuals’ catenation maps were very similar. They all had dense catenation in prefrontal cortex, and moderate catenation in temporal, parietal, and insular cortex. Catenation was lowest in primary cortex and in parietal regions.

I always assumed that brain function had to line up with cytoarchitectonics. It turns out I was wrong. Human cortex, especially PFC, is tiled by chains of functional patches that subdivide and interlink architectonic areas into parallel processing streams. www.biorxiv.org/content/10.6...