Ziyad Al-Aly MD

@zalaly.bsky.social

Physician | Scientist | working on Long Covid

The finding that stopping GLP-1 drugs can undo years of heart protection is resonating. Coverage from CNN, TIME, USA Today, CNBC, Gizmodo, and others. What 3 years of continuous treatment builds, ~1.5 years off the drug can erase.

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For your weekend reading: I wrote about what our BMJ findings mean for addiction — why GLP-1s work across every addictive substance, and how these drugs seem to quiet cravings the same way they quiet food noise. @us.theconversation.com theconversation.com/glp-1-drugs-...

GLP-1 drugs may fight addiction across every major substance, according to a study of 600,000 people

GLP-1 drugs are the first medication to show promise for treating addiction to a wide range of substances.

theconversation.com

Honored to speak at Harvard’s Radcliffe Institute workshop on #LongCOVID. I am energized by our 2 days of brainstorming about the road ahead. The challenges are real, but I’m leaving hopeful. Millions living with Long Covid are counting on our progress—we must keep keep pushing forward!!!

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For decades, the junk food industry has deliberately engineered foods to be addictive. GLP-1 drugs have helped people break free from this cycle. The industry is now searching for ways to undo the effects of these meds, aiming to design foods that remain addictive for those on GLP1. buff.ly/40QHDnk

Ozempic Could Crush the Junk Food Industry. But It Is Fighting Back.

As revolutionary new weight-loss drugs turn consumers off ultraprocessed foods, the industry is on the hunt for new products.

nytimes.com

GLP-1 drugs are revolutionizing the way we think about obesity. It is a chronic disease (like high blood pressure), and might actually be a form of food addiction. One reason these drugs are so effective in treating obesity could be that they address the underlying addiction.

Mapping the effectiveness and risks of GLP-1 receptor agonists - Nature Medicine

An atlas of the associations between the use of GLP-1 receptor agonists (GLP-1RAs) and 175 health outcomes reports the effectiveness and risks of GLP-1RAs compared with other antihyperglycemic…

buff.ly

📄 Free access to the full study: rdcu.be/d6VYU New from my team: In a study of over 2 million people, we comprehensively mapped the benefits and risks of GLP-1 (e.g. Ozempic and similar weight loss drugs) across 175 health conditions. Please share and download before it goes back behind paywall.

Mapping the effectiveness and risks of GLP-1 receptor agonists

Nature Medicine - An atlas of the associations between the use of GLP-1 receptor agonists (GLP-1RAs) and 175 health outcomes reports the effectiveness and risks of GLP-1RAs compared with other...

rdcu.be

My first post has to be about #LongCOVID 🔹 400 million individuals affected worldwide 🔹 $1 trillion in annual economic costs 🔹 Countless lives & communities shattered The time for a comprehensive policy and research response is now! Details in our review here www.nature.com/articles/s41...

Long COVID science, research and policy - Nature Medicine

This Review outlines the current state of scientific evidence on long COVID, discusses its impacts on patients, health systems, economies and global health metrics, and proposes a forward-looking rese...

nature.com