Anna Poetsch
@apoetsch.bsky.social
Computational Biologist at TU Dresden. Interested in how genomes encode their own stability.
We are happy to present a new paper on gene regulation on the way to regenerating the spinal cord www.biorxiv.org/content/10.6... 🧵 1/4
Baseline regulatory programs in larval and adult neural progenitors converge towards an injury-induced state after spinal cord injury
Regeneration after spinal cord injury requires progenitor cells to convert injury-associated signals into coordinated remodeling of gene regulatory programs. Mammalian spinal progenitors show limited ...
biorxiv.org
We are happy to present a new paper on the sequence dependence of 🧬 replication timing in the cell cycle. www.biorxiv.org/content/10.6... 🧵 1/6
Using Deep Learning to predict replication timing reveals baseline control of genomic DNA sequence
Human DNA replicates according to a precise schedule: certain regions are replicated early, while others replicate later in the cell cycle. The DNA sequence and the epigenome are both indicative for r...
biorxiv.org
We are looking for a Data and IT manager. You would set up the group’s data infrastructure, data flows, and overall organization on HPC. We aim to understand genomes 🧬 and ageing 👵 with Big Data and Machine / Deep Learning. Interested? Please apply through jobportal.uni-koeln.de/ausschreibun...
🎉Zwei Sonderforschungsbereiche an der Universität zu Köln werden verlängert 🌱🧬Der Sonderforschungsbereich (SFB) 1530 „Aufklärung und Targeting pathogener Mechanismen bei B-Zell-Neoplasien“ und der SFB/TRR 341 „Ökologische Genetik der Pflanzen“ gehen in die zweite Förderperiode ▶️ uni.koeln/J5KLR
A bit more than a week to apply 🧬💻 Also stay tuned for more adds, there will be one for a single cell multiomics postdoc 🧫and one for a Data & IT manager 📈
Anna Poetsch@apoetsch.bsky.social · 3mo agoAre you looking for a new challenge? We are looking for a Deep Learning Engineer. With this role you would set up deep learning infrastructures with the goal to understand genomes 🧬 and ageing 👵 .
Our field has lost a giant. I will never forget his talk I heard as a master student in Tokyo. It was very inspiring for someone so young. However, I am not sure how much the rest of the audience benefited - the French accent was superb, too 🇫🇷 Anyway, I asked the only question 🤭
Alexis Verger 🧬🧫🧪@alexis-verger.cpesr.fr · 3mo ago#RIP Pierre Chambon (1931-2026) 1963 PARP 1970 RNA Pol II 1975 Nucleosome 1977 Split genes 1980 Promoter 1983 enhancer 1986 Nuclear receptor
SLX4IP acts as a genome-wide brake on BLM helicase activity to preserve replication fork stability under stress – both globally and at ALT telomeres Stephanie Panier @spanier55.bsky.social, Kavi Mehta @k4v1.bsky.social and coworkers link.springer.com/article/10.1...
SLX4IP limits replication stress globally and at ALT telomeres - The EMBO Journal
Faithful DNA replication is essential for genome stability, yet replication forks face constant stress. The Bloom syndrome helicase (BLM) safeguards fork integrity, but excessive BLM activity can itse...
link.springer.com
Connecting fragmented aging research through the European Federation for Aging Research | Nature Aging. Read here how EFAR will provide a new platform for the geroscience community Morten Scheibye-Knudsen , Lene Rasmussen, Folkert Kuipers www.nature.com/articles/s43...
Connecting fragmented aging research through the European Federation for Aging Research - Nature Aging
Nature Aging - Connecting fragmented aging research through the European Federation for Aging Research
nature.com
Are you looking for a new challenge? We are looking for a Deep Learning Engineer. With this role you would set up deep learning infrastructures with the goal to understand genomes 🧬 and ageing 👵 .
Medical data protection is important and I do understand that the German laws for doing research with them are rather strict. But why is it allowed that private health insurances insist on you signing to lift all restrictions and allow them to store everything forever?
I am delighted, humbled, proud, and grateful to let you know that I became a professor for life today. I am very aware of the privilege that this position now brings to my life. I will do my best to pay forward the kindness and support of the people who got me here.
I love this initiative. I think generally it would be great to have a grant system for providing basic income, if private citizens propose something that enriches society. This could be art, literature, building up something. It may even make sense for doing science or humanities.
gisele600.bsky.social@gisele600.bsky.social · 5mo agoIreland decided to grant 2000 artists a guaranteed income and found that for every euro invested, the return to the economy was 1.39 euros. They are working on making it permanent: www.theguardian.com/commentisfre... #AcademicSky #universal #news
🚨 Speaker Alert! 🚨 We’re excited to welcome Dr. Anna Poetsch to our upcoming #CRC1678 Seminar 🧬DNA Language Models to Understand the Biology of Genomes 📅 March 5 📍 CECAD Lecture Hall ⏰ 2:30 PM Join us for fresh insights at the intersection of computational biology and genomics. Don't miss out!
Lieber @bundestag.de , für viele ist der #ÖPNV essenzielle Infrastruktur. Warum darf der überhaupt bestreikt werden?
🧬🧬🧬 REGISTRATION JUST OPENED! Make sure you join our DNA REPAIR MEETING 2026 ON PHYSIOLOGICAL CAUSES AND CONSEQUENCES OF GENOME INSTABILITY in Cologne, September 7-9, organized by the German Society for DNA Repair (DGDR) and the @dfg.de Research Unit 5504. www.for-5504.com/en/197/Confe...
Are you interested in @ceplas.bsky.social single cell data and spatial transcriptomic data analysis and inference? Then apply for this PhD position in our graduate school HDS-LEE in my group co-supervised by Prof Assent. www.fz-juelich.de/en/careers/j.... For questions don't hesitate to contact me.
PhD position - Co-regulation structures for large-scale single-cell transcriptomics - within the HDS-LEE graduate school
The Bioinformatics Division of the Institute of Biological and Geosciences (IBG-4) processes and develops methods and algorithms to achieve a fundamental understanding of high-dimensional data and pro...
fz-juelich.de
You did not get your #MSCA and you are upset, because you really wanted to work on somatic cell evolution on the way to malignancy with single cell data and 🧬machine learning 💻? Then get in touch! There are other ways to fund a postdoc ;-)
Are you interested to hear about DNA Language Models (in German)? Then I would have apodcadt for you. It was a really nice conversation and I hope you’ll like it! www.ghga.de/de/codedesle...
GHGA Podcast: Der Code des Lebens
Der Code des Lebens – der Wissenschaftspodcast von GHGA beschäftigt sich mit verschiedenen Aspekten der menschliche Genomforschung. Wie ist unser Erbgut entstanden? Wie funktioniert Genomforschung und...
ghga.de
Come to Germany and do a PhD with DKFZ. You'll be supported by an international community doing amazing science in a fantastic place. I joined the DKTK from the UK 3 months ago and couldn't be happier with how easy it has been fitting in. The quality of work here is phenomenal and you should apply!
Deutsches Krebsforschungszentrum (DKFZ)@dkfz.bsky.social · 9mo ago🚀 Thinking about your next big career step in science? The Int'l PhD Program at DKFZ could be a perfect fit for you. 🌍 Work in an international environment, with 500+ doctoral researchers 🔬 Do cutting-edge cancer research Curious? Join our online info session on 20 Nov. Register here: t1p.de/ws7q3
Congratulations @vakil-takhaveev.bsky.social @sturlalab.bsky.social and everyone else involved. It was really a pleasure to play a small part in it. I am looking forward to celebrating the next time we meet!
Vakil Takhaveev@vakil-takhaveev.bsky.social · 9mo agoNew publication alert! Click-code-seq, our DNA-damage sequencing method, is now out! This tool can advance our understanding of aging, cancer and neurodegeneration. Huge thanks to the amazing collaborative team behind this! @sturlalab.bsky.social @ethz.ch
Click-code-seq reveals strand biases of DNA oxidation and depurination in human genome. #DNAoxidation #HumanGenome @natchembio.nature.com www.nature.com/articles/s41...
I am looking to get my hands on some #Illumina 5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
It was a pleasure to talk Genome Stability for a few days with the DFG - FOR5504 for. It is really exciting to see the community in and around Cologne looking for genome stability in whole organisms and the context of the sequence. I am excited about what else is going to come.
Björn Schumacher@bjornschumacher.bsky.social · 10mo agoAmazing retreat of the @dfg.de Research Unit FOR5504 on the Physiological Causes and Consequences of Genome Instability and the Institute for Genome Stability in Aging and Disease with keynotes by @apoetsch.bsky.social and @garinis.bsky.social
Me: I got a new type of compliment from an audience member: "Your talk was so Gen Z" My lab: This was not a compliment... Me: 🥲 (but..., but..., I still think it was meant to be one...)
I am happy to share some thoughts on using AI to generate viruses (in German). www.spiegel.de/wissenschaft...
(S+) Künstliche Intelligenz: KI-designtes Virus tötet Kolibakterien
US-Forscher haben mithilfe von künstlicher Intelligenz Viren hergestellt und ihnen bestimmte Eigenschaften gegeben, weltweit sind sie damit wohl die Ersten. Die Möglichkeit KI-generierten Lebens schei...
spiegel.de
The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German). www.swr.de/leben/gesund...
Die ersten KI-generierten Viren als Hoffnung im Kampf gegen resistente Bakterien
Forschende aus Stanford haben erstmals Viren entwickelt, die von einer KI entworfen wurden. Einige dieser KI-Viren konnten antibiotikaresistente Bakterien infizieren und abtöten - ein möglicher Durchb...
swr.de
There is a new Master of Physics of Life in the house. Congratulations, Adnan! Well done! It was really a superb Defense! @poldresden.bsky.social
The ARD Wissenschaftsredaktion talked to me about AI generated viruses. Interested? Here you can listen to it (in German). www.swr.de/leben/gesund...
Die ersten KI-generierten Viren als Hoffnung im Kampf gegen resistente Bakterien
Forschende aus Stanford haben erstmals Viren entwickelt, die von einer KI entworfen wurden. Einige dieser KI-Viren konnten antibiotikaresistente Bakterien infizieren und abtöten - ein möglicher Durchb...
swr.de
I am happy to share some thoughts on using AI to generate viruses (in German). www.spiegel.de/wissenschaft...
(S+) Künstliche Intelligenz: KI-designtes Virus tötet Kolibakterien
US-Forscher haben mithilfe von künstlicher Intelligenz Viren hergestellt und ihnen bestimmte Eigenschaften gegeben, weltweit sind sie damit wohl die Ersten. Die Möglichkeit KI-generierten Lebens schei...
spiegel.de
Dear CRC TRR 341, thanks for having me. It was fascinating to learn more about the genomes of plants in their ecological context!
CRC TRR 341 "Plant Ecological Genetics"@trr341.bsky.social · 11mo agoOur 5th Internal Progress Colloquium is coming to an end! Two days full of scientific interactions. Honoured to have with us Caroline Müller (Bielefeld University) and @apoetsch.bsky.social! Our ECRs have progressed enormously and this makes us so happy!
