Here is the direct link to the recent Advanced Science paper from the lab of Daniela Duarte Campos describing a methodology for generating and evaluating acoustically patterned 3D vascular tissue: advanced.onlinelibrary.wiley.com/doi/10.1002/...

Quality Thresholds for Angiogenesis Under Acoustic Manipulation in Engineered Vascular Tissues

Defined biological and physical quality thresholds achieved through acoustic manipulation regulate cellular alignment and spatial organization, promoting self-assembling vasculature, extracellular ma...

advanced.onlinelibrary.wiley.com

This is work on vascular tissue engineering from the labs of Daniela Duarte Campos @zmbh.uni-heidelberg.de . We will share the paper in the follow-up post.

Universität Heidelberg@uniheidelberg.bsky.social · 3w ago

Steering the Formation of Engineered Tissue by Sound Waves – Heidelberg scientists show that functional vascular networks can be generated by acoustic manipulation www.uni-heidelberg.de/en/newsroom/...

Get an update on the research of the @voegtlelab.bsky.social at ZMBH by joining the virtual GBM Lunch Talk next Wednesday. Also open to non GBM members but the GBM always welcomes new members supporting their work.

GBM (Gesellschaft für Biochemie und Molekularbiologie)@gbmev.bsky.social · 2mo ago

GBM Lunch on June 17 (12:30 pm) Speaker: Nora Vögtle (@zmbh.uni-heidelberg.de) Title: Sensing and shaping mitochondrial function: Proteolytic control and stress surveillance Chair: Johannes Herrmann (RPTU) Organizer: GBM Study Group "Cellular Organelles" #Mitochondria #GBMLunch #Organelles

The ZMBH welcomes Dr. James Sáenz @jamessaenz.bsky.social as new Professor in Molecular Biology. James previously led a research group at B CUBE - Center for Molecular Bioengineering of Dresden University of Technology.

The Vögtle lab @voegtlelab.bsky.social and collaborators discovered that physiological stress signals are directly detected by intra-mitochondrial surveillance mechanisms triggering the mitochondrial unfolded protein response UPRmt. The study is online in Mol Cell: www.cell.com/molecular-ce...

Uncovering the initial response: Intra-mitochondrial surveillance activates the UPRmt

Taskin, Shankar, Peselj, et al. demonstrate that mitochondria possess an intrinsic surveillance system that senses mild oxidative stress and activates the UPRmt before damage signals reach the cytosol...

cell.com

The ZMBH community congratulates Henrik Kaessmann on being awarded the Ernst Schering Prize 2026!

Kaessmann Lab@kaessmannlab.bsky.social · 2mo ago

Thrilled and honored to receive the Ernst Schering Prize 2026!🎉 Also deeply grateful to have been elected to the German Academy of Sciences. Both are recognitions of our whole group – I’m immensely thankful to all team members, past and present!❤️ tinyurl.com/hjrejv3p tinyurl.com/muw7j6mr

Congratulations to Henrik Kaessmann having been appointed to the German National Academy of Sciences Leopoldina as a member of the section "Organismic and Evolutionary Biology"!

“Ideal Facilities for State-of-the-Art Teaching”: Official opening ceremony for audiMAX, the new lecture hall and study center on the Im Neuenheimer Feld campus www.uni-heidelberg.de/en/newsroom/...

Bukau and Kramer labs show in an international collaborative project how NAC promotes co-translational protein folding at the ribosomal tunnel exit: Molecular Cell www.cell.com/molecular-ce...

NAC promotes co-translational protein folding at the ribosomal tunnel exit

Santos et al. reveal NAC’s co-translational interactome, showing compartment-specific nascent chain interactions in human cells. NAC engages emerging chains at the ribosomal tunnel exit via a ribosome...

cell.com

We are are searching a scientific manager for the ZMBH. This position requires a life sciences PhD & excellent German skills, therefore the advertisement is formulated in German. Very good English skills are needed as well. You are welcome to share the ad: www.academics.de/jobs/wissens...

Wissenschaftliche*r Geschäftsführer*in (w/m/d) - Zentrum für Molekulare Biologie der Universität Heidelberg - Universität Heidelberg

Universität Heidelberg bietet Stelle als Wissenschaftliche*r Geschäftsführer*in (w/m/d) - Zentrum für Molekulare Biologie der Universität Heidelberg in Heidelberg - jetzt bewerben!

academics.de

Important insights into brain development and evolution are out by the @kaessmannlab.bsky.social: The evolution of gene regulation in mammalian cerebellum development | Science www.science.org/doi/10.1126/...

The evolution of gene regulation in mammalian cerebellum development

Gene regulatory changes are considered major drivers of evolutionary innovations, including the cerebellum’s expansion during human evolution, yet they remain largely unexplored. In this study, we com...

science.org

We invite applications for a Tenure Track Professorship (W1->W3) in Molecular Biology @ZMBH. We are looking for excellent postdocs, ready to start their own research group. Feel free to spread the news by reposting. Applications can be filed until January 18th. www.nature.com/naturecareer...

Tenure Track Professorship (W1 with Tenure Track to W3) in “Molecular Biology" (f/m/d) - Heidelberg job with Universität Heidelberg | 12850668

The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a   Tenure Track Professors...

nature.com

Congratulations to former ZMBH Research Group Leader & Professor Dirk Görlich on receiving the 2025 Albert Lasker Basic Medical Research Award for work that he and his team started when working at ZMBH. laskerfoundation.org/winners/stru...

Structures and functions of low-complexity domains - Lasker Foundation

For their discovery of the two distinct classes of lymphocytes, B and T cells – a monumental achievement that provided the organizing principle of the adaptive immune system and launched the course of...

laskerfoundation.org

The Duarte Campos lab has developed a novel protocol for the differentiation of mesenchymal stromal cells into corneal stromal keratocytes. These findings have been published in Advanced Healthcare Materials: doi.org/10.1002/adhm...

3D Differentiation of Bone‐Marrow Derived Mesenchymal Stromal Cells into the Keratocyte Lineage for Corneal Bioprinting

This study introduces a novel differentiation protocol for generating corneal stromal keratocyte-like cells using drop-on-demand bioprinting and a collagen-based hydrogel. The bioprinted constructs m...

doi.org

@kaessmannlab.bsky.social has for the first time shown in an international collaboration, that survival of male birds crucially depends on a micro RNA for sex chromosome dosage compensation. The paper just has been published by Nature. www.nature.com/articles/s41...

A male-essential miRNA is key for avian sex chromosome dosage compensation - Nature

Birds have evolved a unique sex chromosome dosage compensation mechanism involving the male-biased microRNA (miR-2954), which is essential for male survival by regulating the expression of dosage-sens...

nature.com

Congratulations to Claudio Joazeiro @labjoazeiro.bsky.social being awarded an ERC Advanced Grant @erc.europa.eu. He is one of five scientists from @uniheidelberg.bsky.social who were successful in this round. www.uni-heidelberg.de/en/newsroom/... #ERCAdG #uniheidelberg #Universität #heidelberg

50 Years of Cell Biology: German Society for Cell Biology Meeting, October 26 – 29, 2025 | Heidelberg, Germany Early bird registration deadline: June 15, 2025

The ZMBH welcomes Daniel Schindler @danielschindler.bsky.social as new Professor in Microbiology joining us from Marburg's Max Planck Institute for Terrestrial Microbiology.

ZMBH research group leader Henrik Kaessmann @kaessmannlab.bsky.social has given a talk on the origin of humans for a general audience. This presentation is available on YouTube (in German): www.youtube.com/watch?v=WuYl...

Henrik Kaessmann: Der Ursprung des Menschen – ein Unfall der Evolution?

YouTube video by DAI Heidelberg

youtube.com

There is a German language video of a TV discussion on "Biology From the Building Block" in which ZMBH's Kerstin Goepfrich @kgoepfrich.bsky.social was one of the two invided experts: www.3sat.de/wissen/scobe...

Biologie aus dem Baukasten

Ingenieure, Informatiker, Chemiker und Biologen kreieren künstliche biologische Systeme. Die synthetische Biologie verändert die Zukunft und definiert die Grenzen der Wissenschaft neu.

3sat.de

Another study has been published in Nat. Commun. by @pfeffercryolab.bsky.social. Collaborative work with @sergeymelnikov.bsky.social and @chillzaa.bsky.social from the UK looking at structural ribosome heterogeneity in bacteria and if this has an impact on function: www.nature.com/articles/s41...

Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells - Nature Communications

Cells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...

nature.com

The Goepfrich lab @kgoepfrich.bsky.social yesterday published the creation of cytoskeleton-like structures with different properties inside lipid vesicles using RNA origami: www.nature.com/articles/s41...

Genetic encoding and expression of RNA origami cytoskeletons in synthetic cells - Nature Nanotechnology

This study introduces RNA origami nanotubes as self-assembling cytoskeleton mimics for synthetic cells. Expressed in vesicles from DNA templates, these RNA structures reach micrometre lengths, deform ...

nature.com

Work from ZMBH's @pfeffercryolab.bsky.social & the Schiebel lab togehter with the Gruss lab @unibonn.bsky.social reveals the structural mechanisms for centrosomal recruitment and organization of the human microtubule nucleator γ-TuRC: www.nature.com/articles/s41...

Structural mechanisms for centrosomal recruitment and organization of the microtubule nucleator γ-TuRC - Nature Communications

The γ-TuRC plays a central role for nucleation of microtubules at the centrosome. Here, the authors dissect structural mechanisms for centrosomal recruitment and regulation of the γ-TuRC and identify ...

nature.com

Today's Science paper by @kaessmannlab.bsky.social and two additional papers in the same iusse analyze the development of complex neural circuits in reptiles, birds, and mammals. These studies suggest that observed similarities result of evolutionary convergence. www.science.org/doi/10.1126/...

Developmental origins and evolution of pallial cell types and structures in birds

Innovations in the pallium likely facilitated the evolution of advanced cognitive abilities in birds. We therefore scrutinized its cellular composition and evolution using cell type atlases from chick...

science.org

We are recruiting a Full Professor in Molecular Biology with a focus on Biological Engineering. Details can be read up in the advertisement on Nature Careers. Please share with researchers who are active in this field. go.nature.com/41IHN0i

Full Professorship (W3) in Molecular Biology (f/m/d) with a Focus on Biological Engineering - 69117, Heidelberg (DE) job with Universität Heidelberg | 12834054

The Center for Molecular Biology of Heidelberg University (ZMBH), the Carl-Zeiss-Stiftung Center for Synthetic Genomics (CZS Center SynGen), and th...

go.nature.com