I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...

Crazy things have been happening in cilia world, catch up on them in Caitie's new paper! 🪱

Caitie McCafferty@computingcaitie.bsky.social · 4mo ago

I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...

Thrilled to share that our paper on a novel IRD gene has been published in The American Journal of Human Genetics (AJHG)! 🎉 This wouldn’t have been possible without the incredible group of colleagues and collaborators. Special thanks to @computingcaitie.bsky.social, Ditta Zobor, and ERDC members!

IOB - Institute of Molecular and Clinical Ophthalmology Basel@iobswiss.bsky.social · 5mo ago

🧬 New IRD gene identified! IOB researchers (@abimoye.bsky.social, @mquinodoz.bsky.social, @carlorivolta.bsky.social) found pathogenic variants in SAXO6 (formerly MDM1) in families with a rare late-onset retinal degeneration. 🔗 www.cell.com/ajhg/fulltex... #AcademicBlueSky So what’s SAXO6 doing?

I’m happy to share that the latest work from the @carlorivolta.bsky.social lab, thanks to a huge international collaborative effort, is now out in Nature Genetics!🧬 Congratulations to all, but especially to @mquinodoz.bsky.social and @kimrodenburg.bsky.social for leading this impressive work!

No momentum lost as we dazzled with the ciliary necklace, CEP290 and transition zone integrity in #photoreceptors, inner scaffold maintenance & membrane attachment key for gating with the amazing @abimoye.bsky.social (Wensel group and current @carlorivolta.bsky.social ). #IRDs #UKCilia2025 /4

Happy Halloween! Cilia can be spooky too 🎃

Super happy this work is out and included in the really interesting cilia and flagella focused issue!

Journal of Cell Science@jcellsci.bsky.social · 9mo ago

Abigail Moye @abimoye.bsky.social @iobswiss.bsky.social, Theodore Wensel @bcmhouston.bsky.social and colleagues examine the sub-ciliary localisation of CEP290 and dissect the effects of its loss in mouse photoreceptors during development. #JCSciliaSI journals.biologists.com/jcs/article/...

Save the date!! ✨🤩

Mill_lab@cilialab.bsky.social · 10mo ago

🎆 Join us for an unmissable finale to 2025! 🎆 We're thrilled to bring our #cilia & #centrosome community together 25/11/2025 15:00-17:45 GMT! Our 53rd @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposium schedule is live: www.eventbrite.co.uk/e/bscb-genso... /1

🚨 CALL FOR APPLICATIONS 🚨 Looking for your next academic step? Join our interdisciplinary IOB MD-PhD / PhD Program to explore the visual system and pioneer therapies for eye diseases. ⏰ Deadline: November 16, 2025 (midnight CET) 🔗 iob.ch/phd-md-phd-program #IOB #Basel #PhDProgram #VisionScience

I am normally focused on photoreceptor cilia, but this week I worked with an amazing lung epithelial tissue model and I can see the #motilecilia appeal 🤩 so fascinating! Happy #fluorescencefriday everyone!

Looking for a break from scientific reading, and want to delve into the realm of environmental philosophy? Check out this thought-provoking article by Charles Hayes published in Environmental Ethics. Interesting and insightful look into what my brother studies daily! www.pdcnet.org/enviroethics...

New hope for inherited vision loss IOB researchers (@karkam.bsky.social, @carlorivolta.bsky.social, @mquinodoz.bsky.social, @abimoye.bsky.social) identify AP5Z1, AP5M1, AP5B1 mutations, revealing new causes of macular dystrophy. 🔗 www.cell.com/ajhg/fulltex... #AcademicBlueSky #Ophthalmology

Bi-allelic variants in three genes encoding distinct subunits of the vesicular AP-5 complex cause hereditary macular dystrophy

We discovered genetic changes in three genes (AP5Z1, AP5M1, and AP5B1) that cause macular degeneration, affecting sharp central vision. The proteins encoded by these genes form a complex that helps th...

cell.com

Excited to share our ✨preprint✨ from my work in Ted Wensel's lab! We present novel insights into the photoreceptor-specific roles of CEP290. 🧵👇 Thanks for the helpful participation from everyone involved, especially @mrobichaux.bsky.social and @agostolab.bsky.social! www.biorxiv.org/content/10.1...

Great gene editing study from a highly interdisciplinary team at @iobswiss.bsky.social. Congratulation to all authors, in particular Alissa Muller, Botond Roska & Bence György. www.nature.com/articles/s41... #AcademicSky #neuroscience

High-efficiency base editing in the retina in primates and human tissues - Nature Medicine

A base-editing approach optimized to target the retina shows high editing rates in a mouse model of Stargardt disease, as well as in nonhuman primates and ex vivo human retinal explants, paving the wa...

nature.com

IOB - Institute of Molecular and Clinical Ophthalmology Basel@iobswiss.bsky.social · 2y ago

✨Scientific breakthrough: IOB researchers have achieved a significant advance in developing a new treatment for Stargardt disease, the most common form of inherited macular degeneration. Read more: www.nature.com/articles/s41... Watch full movie: iob.ch/news-view-al... #AcademicSky #neuroscience