biorxiv.org

Distinctive DNA sequence features define epigenetic longevity of inflammatory memory

Tissues harbor memories of inflammation, which heighten sensitivity to diverse future assaults. Whether and how these adaptations are sustained through time and cell division remain poorly understood. We show that in mice, epidermal stem cells store ...

science.org

Versatile molecular tools enabling customizable DNA methylation editing in Arabidopsis - Nature Communications

Targeted DNA methylation editing is critical for establishing the causal relationship between DNA methylation and its function as well as for epigenetic crop breeding. Here, the authors develop a CRIS...

nature.com

Genome-wide selection on transposable elements in maize

While most evolutionary research has focused on single nucleotide polymorphisms (SNPs), transposable elements (TEs) represent a major but understudied source of mutations that can influence organismal...

biorxiv.org

SALICYLIC ACID SENSOR1 reveals the propagation of an SA hormone surge during plant pathogen advance

Salicylic acid (SA) is a key phytohormone that orchestrates immune responses against pathogens, including Pseudomonas syringae bacteria. The timing and extent of SA accumulation are tightly controlled...

science.org

Transposable elements are vectors of recurrent transgenerational epigenetic inheritance

DNA methylation loss at transposable elements (TEs) can affect neighboring genes and be epigenetically inherited in plants, yet the determinants and significance of this additional system of inheritan...

doi.org

Gene body methylation regulates gene expression and mediates phenotypic diversity in natural Arabidopsis populations - Nature Plants

This study shows that epigenetic gene body DNA methylation regulates transcription and accounts for much of its variance in the Arabidopsis population, efficiently identifies genes regulating diverse ...

nature.com

From recall to reset: the role of DNA (de)methylation in modulating plant immune memory

Epigenetic reprogramming is increasingly recognised as a driver of plant immune memory, yet its molecular basis remains poorly understood. Using a chemically inducible transgene in Arabidopsis, we tra...

biorxiv.org

Somatic mobility of transposons is explosive and shaped by distinct integration biases in Arabidopsis thaliana

Background The movement of transposable elements (TEs) in somatic cells generates genetic and phenotypic diversity across the soma of individual organisms. This process is especially important in plan...

biorxiv.org

New research aims to unlock stressful plant memories

New research led by Prof Jurriaan Ton aims to uncover how plants adapt and survive in challenging environments with the ultimate goal to create more resilient crops.

sheffield.ac.uk

Herbivory-induced green leaf volatiles increase plant performance through jasmonate-dependent plant–soil feedbacks - Nature Plants

This study reports that herbivory-induced volatiles can trigger plant–soil feedbacks that boost performance and yields of cereals in the field.

nature.com

Extensive N4 cytosine methylation is essential for Marchantia sperm function

Global N4 cytosine methylation in Marchantia polymorpha sperm regulates gene expression and promotes sperm fertility.

cell.com

Misregulation of the jasmonate signaling pathway leads to altered plant microbiota interaction and plant stress responses

The model plant Arabidopsis thaliana hosts diverse microbial communities collectively known as the microbiota. The plant microbiota is generally taxonomically structured. Some of the members can promo...

biorxiv.org

Salt stress activates the CDK8-AHL10-SUVH2/9 module to dynamically regulate salt tolerance in Arabidopsis - Nature Communications

The authors demonstrate that salt stress activates CDK8, which phosphorylates AHL10 and promotes its degradation. AHL10 is involved in recruiting SUVH2/9 to repress salt-responsive genes. The CDK8-AHL...

nature.com

CRISPR targeting of H3K4me3 activates gene expression and unlocks centromeric crossover recombination in Arabidopsis

H3K4me3 is a fundamental and highly conserved chromatin mark across eukaryotes, playing a central role in many genome-related processes, including transcription, maintenance of cell identity, DNA dama...

shorturl.at

Histone H3 lysine 4 methylation recruits DNA demethylases to enforce gene expression in Arabidopsis - Nature Plants

This study revealed that targeting H3K4me3 via the H3K4 methyltransferase SDG2 activates gene expression and removes DNA methylation by recruiting DNA demethylases. Conversely, the removal of H3K4me3 ...

nature.com

Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis - Nature

An Arabidopsis long terminal repeat retrotransposon integrates de novo into regions occupied by centromere-specific histone variant, showing the impact of centromeric chromatin on transposable element...

nature.com

Transposon-triggered epigenetic chromatin dynamics modulate EFR-related pathogen response - Nature Structural & Molecular Biology

Here, the authors show that an inverted-repeat transposon located next to the pattern recognition receptor ELONGATION FACTOR-TU RECEPTOR (EFR)-encoding gene in Arabidopsis controls chromatin organizat...

nature.com

ACCE+ DLA programme - EpiPlasticity: exploring the ecological and evolutionary significance of epigenetic defence plasticity at University of Sheffield on FindAPhD.com

PhD Project - ACCE+ DLA programme - EpiPlasticity: exploring the ecological and evolutionary significance of epigenetic defence plasticity at University of Sheffield, listed on FindAPhD.com

findaphd.com

Retrotransposon-driven environmental regulation of FLC leads to adaptive response to herbicide - Nature Plants

This study reports the discovery of a retrotransposon insertion in the FLC gene conferring an environmentally dependent control mechanism mediated by DNA methylation that drives the adaptation of natu...

nature.com