Our latest work is now online in NSMB: maternal yolk carries microRNAs from the intestine to embryos, shaping gene regulation and stress resilience in the next generation. rdcu.be/fj8Er #Epigenetics #microRNA #Inheritance @pasteur.fr @devstempasteur.bsky.social @erc.europa.eu

Soma-to-germline miRNA inheritance through yolk promotes stress resilience in progeny - Nature Structural & Molecular Biology

In this study, the authors use the Caenorhabditis elegans model organism to show that maternal microRNAs are delivered from the intestine to embryos by the yolk, where they regulate gene expression an...

nature.com

Love Drosophila genetics — this journal club was a great way to share that enthusiasm and pay tribute to the pioneers of transposons regulation 🪰 How classical genetics uncovered key determinants of TE silencing #transposon @igred.fr @igred.fr 👇👇

Nature Reviews Genetics@natrevgenet.nature.com · 4mo ago

New online! How classical genetics uncovered key determinants of TE silencing

Our latest publication is now out at Genome Biology! link.springer.com/article/10.1... We uncover a unique association between a H3K27me3 reader complex and active transcription. A thread with our key findings: (1/8) #TEsky #Polycomb #transcription #smallRNAs

A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium - Genome Biology

Background The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2). This is largely attributed to Polycomb repres...

link.springer.com

Really cool paper from Marie-Anne Felix's lab. Genetic variation in set-24 controls the duration of epigenetic inheritance. www.cell.com/current-biol...

Intraspecific variation in the duration of epigenetic inheritance in wild isolates of C. elegans

Frejacques, Saglio, et al. demonstrate variation among C. elegans wild isolates in the multigenerational memory of an initial RNA interference trigger. Genetic polymorphisms and environmental variable...

cell.com

🌱 🚨Postdoc position – Plant Chromatin Biology (Strasbourg) Grob and Jullien Lab - details attached 📅 Apply by March 30, 2026 📩 stefan.grob@cnrs.fr Please share with anyone who might be interested! #Postdoc #PlantScience #Epigenetics #Chromatin

Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

Dear postdoc fellows, interested in applying for MSCA Postdoc Fellowship with team Epi2Trans at LGDP CNRS/UPVD in Perpignan, France? Get in touch with us! #MSCA #Postdoctoral #PlantScience #Epigenetics #TransposableElements #CNRS #UPVD www.linkedin.com/in/guillaume...

Need a bit of escapism? Not exactly Lord of the Rings, but in similar vein: doi.org/10.1038/s443...

Epimutations: raw material for evolution? - The EMBO Journal

Epigenetics is fundamental to cell differentiation as it enables cells with identical genomes to adopt distinct fates. Some epigenetic information can also be transmitted between generations, in a pro...

link.springer.com

Have we been overstating the role of transposable elements in adaptation to local or rapidly changing environmental conditions? Happy to share my (somewhat unpopular?) opinion paper on this matter: www.sciencedirect.com/science/arti... Thanks to those who already shared the link!

Blinded by the lights? Re-examining the adaptive role of transposable elements in plants with population genomics

Transposable elements (TEs) are ubiquitous components of the genome whose mobility can be triggered by environmental stress and influenced by genotype…

sciencedirect.com

We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes. Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...

Next generation of 1001 Genomes Plus browser and data download

Please indicate all features you would like to see in a browser that displays features of completely sequenced Arabidopsis thaliana genomes

docs.google.com

If you're in Ghent tomorrow ! I'll be sharing our recent progress deciphering the sRNA-based dominance/recessivity interactions at the self-incompatibility locus in Arabidopsis 🌱

Plant Systems Biology@psb-vib.bsky.social · 9mo ago

TOMORROW: SEMINAR by @vincentcastric.bsky.social from @univlille.bsky.social @cnrs.fr, invited by @pnovik.bsky.social and @yvdp.bsky.social. @viblifesciences.bsky.social

I recently moved my lab to Purdue University and am looking for graduate students. We are working at the interface of population genomics, quantitative genetics and functional genomics to understand how plants adapt to extreme environments. Reach out if you would like to discuss potential projects.

Out after peer review, collaborative study from Nordborg & Weigel labs with help from many others. Not the largest collection of new Arabidopsis thaliana genomes, but we hopefully put forward some good ideas for how to think about pangenomes and their analysis! www.nature.com/articles/s41...

Excellent work from @piotraz.bsky.social group demonstrating juxtaposition of heterozygous & homozygous regions in maize attracts meiotic recombination to het regions rdcu.be/eHmn9 @natplants.nature.com builds from work we did together in Cambridge on Arabidopsis way back in 2015. Great stuff Piotr!

Enhancing local meiotic crossovers in Arabidopsis and maize through juxtaposition of heterozygous and homozygous regions

Nature Plants - This study discovered that locally confined DNA differences boost crossover rates in both Arabidopsis and maize, revealing a conserved mechanism that can accelerate plant breeding...

rdcu.be

Happy to share the results of a long-haul post-doc project, now online @science.org, aiming at understanding the rules of transgeneration epigenetic inheritance over TEs in plants and its extent and impact in nature. More below! doi.org/10.1126/scie...

Transposable elements are vectors of recurrent transgenerational epigenetic inheritance

DNA methylation loss at transposable elements (TEs) can affect neighboring genes and be epigenetically inherited in plants, yet the determinants and significance of this additional system of inheritan...

doi.org

📢Call for Junior Professor Chair in Neuroscience (tenure track position) @psl-univ.bsky.social is launching a call for applications for a Junior Professor Chair in Life Sciences entitled “Neurosciences”, to be based at #IBENS Deadline: September 30th, 2025 4pm www.bio.ens.psl.eu/depbio/spip....

1/2 Somatic TE transposition in plants is getting traction again (70 years after McClintock's discovery of "controlling elements")! A very large collection of somatic TE insertions in A. thaliana described by Ambreen et al.(www.biorxiv.org/content/10.1...).

I’m very happy to share the published version of our paper on the role of MET1 in wheat 🌾 🧬 It’s been really exciting to discover more about DNA methylation in wheat and it’s huge polyploid genome doi.org/10.1093/jxb/...

Partial redundancy buffers deleterious effects of mutating DNA methyltransferase 1-1 (MET1-1) in polyploid wheat

Varying gene dosage through mutating DNA methyltransferase 1-1 (MET1-1 ) in polyploid wheat generates quantitative changes to CG methylation without the le

doi.org

Interested in the contribution of TEs to the evolution of regulatory pathways in plants? 2-year post-doc position open in URGI in Versailles! jobs.inrae.fr/en/ot-23441 @johannconfais.bsky.social

Announcing a curated collection of long-read genomes for Arabidopsis thaliana: The 1001 Genomes Plus Project. Currently 453 unique accessions/almost 600 assemblies. Interested in contributing? Please contact us! #plantscience www.biorxiv.org/content/10.1...

Postdoc jobs in the Gaut lab! Brandon isn't on here, so I can be frank: he is fantastic. I did my postdoc with him and he is not only an amazing scientist but one of my favorite humans. I would have happily stayed in his lab forever if that was feasible. recruit.ap.uci.edu/JPF08999 #plantscijobs