they really said "they should have sent a poet"

Katie Mack@astrokatie.com · 4mo ago

#Artemis crew to Mission Control, after seeing and attempting to describe the eclipse: "And if you could give me about 20 new superlatives in the mission summary tomorrow, that'll help my vocabulary out a bit. Thank you."

Post a pic, no context, to bring some zen to the feed.

@ohpipedown.bsky.social · 5mo ago

Post a pic you took, no context, to bring some zen to the feed.

Shout this from the rooftops! ALSO: PIs who must decline reviews, please nominate the qualified students and postdocs from your lab!

Mike Moore@moore-evo-eco.bsky.social · 7mo ago

A plea from an editor: postdocs & grad students who want to review manuscripts, please (!) have an online presence with your current email. I try to solicit reviews from ECRs, but we all move a lot, and it's hard to know if we'll be able to reach you at the email address on your last paper 🧪🌍

As I hurtle headlong towards the coming semester, I am really feeling these epic closing words of advice from Gian-Carlo Rota. [very grateful to the transcription from Leo Goldmakher, h/t @lianafaye.bsky.social] web.williams.edu/Mathematics/...

Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/ www.science.org/doi/10.1126/...

Intracellular competition shapes plasmid population dynamics

From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...

science.org

Thank you Adam Maclean @adamlmaclean.bsky.social for sharing your experience of fee-free Open Access publishing in @dev-journal.bsky.social via our Read & Publish agreement with The University of Queensland. See all institutions: www.biologists.com/library-hub/... #OA #OpenAccess #ReadAndPublish

The ability of kids to convince me they know more than they know is truly amazing. Exhibit: family charades. I am acting, 7yo is guessing. One word; two syllables. Meaning: something you eat with that is not a spoon. First syllable: chop. Second syllable: rhymes with lick. 7yo: Knife!

Cool paper. Was the ad hominem really necessary though? www.science.org/doi/10.1126/...

Really enjoyed talking about mathematical biology (and a little about being an associate dean) in @parmvir.com's Biology in Numbers podcast on the 2025 @smbmathbiology.bsky.social annual meeting! Bolero superfans, don't @ me! 🧪 (I'm at 33:43) podcasts.apple.com/us/podcast/b...

S3 Ep1: SMB 2025

Podcast Episode · Biology in Numbers · 09/29/2025 · 53m

podcasts.apple.com

Please start following @natbiomedeng.nature.com! It's an alive account now and we will start posting good content!

This was fun and great to learn about the research (and trivia) of colleagues from #SMB2025 this summer in Edmonton. Thanks to @parmvir.com for hosting a great podcast 🙌 🧬 🔢 podcasts.apple.com/us/podcast/s...

S3 Ep1: SMB 2025

Podcast Episode · Biology in Numbers · 09/29/2025 · 53m

podcasts.apple.com

Parmvir K Bahia@parmvir.com · 10mo ago

Also starring: @adamlmaclean.bsky.social @gosiaweh.bsky.social @mathcancer.bsky.social @thomasewoolley.bsky.social Luis Sordo Vieira Mobolaji Williams Kira Pugh and Francisca Olajide @smbmathbiology.bsky.social #scicomm #BiologyInNumbers

Also starring: @adamlmaclean.bsky.social @gosiaweh.bsky.social @mathcancer.bsky.social @thomasewoolley.bsky.social Luis Sordo Vieira Mobolaji Williams Kira Pugh and Francisca Olajide @smbmathbiology.bsky.social #scicomm #BiologyInNumbers

Parmvir K Bahia@parmvir.com · 10mo ago

This year's @smbmathbiology.bsky.social meeting provided us with another delightful mashup of math biologists (and me) talking about science, and in Amy's case, ultra-running and conference coffee ☕ Thanks to all the excellent attendees who agreed to speak with me for Biology in Numbers. #scicomm

Phylogenetic tree inference from single-cell RNA sequencing data www.biorxiv.org/content/10.1... #singlecell

Super excited to see our reference bias work out in Cell! Reviewers gave us some excellent ideas, and Maria added on some new analyses that broke down how SNPs from heterospecific references mapped or did not map in a conspecific reference.

Maria Akopyan, PhD@akopyan.bsky.social · 11mo ago

Now published in Cell! We found that ~15% of SNPs from divergent refs did not liftover as SNPs in the gray fox ref—half mapped to monomorphic sites, half failed to map. Co-authored with Matthew Genchev, @elliecat.bsky.social, and @jazlynmooney.bsky.social www.sciencedirect.com/science/arti...

Sometimes I get the feeling I'm working in the wrong subfield of biology www.cell.com/current-biol...

Wound-dependent leg amputations to combat infections in an ant society

Frank et al. provide the first example of the use of amputations to treat infected leg wounds in a non-human animal. The findings demonstrate that ants can adapt their treatment modality depending on ...

cell.com

Online now! Tumor dynamics & spatial proteomics-informed personalized predictions of growth & response Beyond RECIST: mathematical modeling and Bayesian inference reveal the importance of immune parameters in metastatic breast cancer www.biorxiv.org/content/10.1...

"When they see us coming The birdies all try an' hide But they still go for peanuts When coated with cyanide."

In this week's post Jesse Kreger (@adamlmaclean.bsky.social‬) discusses his latest work in #cancer #systems #immunology together with Edgar Gonzalez to study the mechanisms of response of breast cancer to #checkPointInhibitors

Discovering mechanisms of response via CSI (Cancer Systems Immunology)

mathematical-oncology.org

mathematical-oncology.org

Couldn't leave Canada without breakfast poutine. Some scattered thoughts and Takeaways from #SMB2025... I had a super fun week, so many conversations, short and long, with science friends old and new.

This is such a cool paper and dataset from lab of @arjunraj.bsky.social. There are [ahem] a lot of spatial transcriptomics papers out there. Here's a [rare?] example of one from which we can truly learn some interesting things... www.biorxiv.org/content/10.1...

Single-cell spatial mapping reveals reproducible cell type organization and spatially-dependent gene expression in gastruloids

Gastruloids are three-dimensional stem-cell-based models that recapitulate key aspects of mammalian gastrulation, including formation of an anterior-posterior (AP) axis. However, we do not have detail...

biorxiv.org

Mohit Jolly kicking off the last day of #SMB2025 presenting a compelling case for understanding EMT via gene exp "teams" Ending with a heartfelt shoutout to the 'SMB team' Q: Which is more important: the journey or the destination? A: the company.

Fantastic plenary this morning from @yosoykit.bsky.social highlighting the power of stochastic processes to inform clinical decision-making in gastrointestinal cancers. #SMB2025

Kicking off day 2 is plenary from Fred Adler with some lovely badly-drawn diagrams, always great to see alternatives to the hegemony of the diagrammatically bland biorender et al. #SMB2025

#medicaid HT The New Yorker

"Patients should be their own control" - great & pithy takeaway from @sandyanderson.bsky.social in his talk on the adoption of adaptive therapies in the clinic #SMB2025 #MathOnco

Next up is former student & friend @stroblmar.bsky.social presenting new work with @cancerconnector.bsky.social on “Bridging the gap: What preclinical experiments can teach us about cancer drug scheduling” #MathOnco #SMB2025

#SMB2025 check out this app to manage your minisymposia scheduling (always an intricate dance to get to all the interesting talks) ...also offers talk recommendations and "poster buddies"

Nisheet Patel@nisheet.bsky.social · last yr.

Try posting on the app: beta.axy-app.com/smb2025

... 🎤 👈 hello? Is #SMB2025 a thing? Are people* here? *society for mathematical biologists that is; nothing against single-molecule biophysicists per se.

Out now @dev-journal.bsky.social Transition paths across the epithelial-mesenchymal transition landscape are dictated by network logic Through investigation into the role of logic in GRN models, we discovered that choice of logic (AND vs OR) profoundly impacts cell fate. doi.org/10.1242/dev....

Transition paths across the epithelial-mesenchymal transition landscape are dictated by network logic

Summary: Mathematical models of gene regulatory networks make assumptions about how signals combine logically; great caution must be taken in this choice of logic, as it can lead to divergent phenotyp...

doi.org

Adam MacLean@adamlmaclean.bsky.social · last yr.

Celebrate every win. Ideally with beer. Congratulations to Anupam. His first postdoc paper out of the lab was accepted today. Coming soon..…

next time I reply to a conceptually tricky reviewer 2 question, for which I have a less-than-perfect answer, I am sorely tempted to steal this line. "Having been weaned intellectually on these distinctions and others like them, I could scarcely be more aware of their import and force" - T.S. Kuhn