Live from the backyard: Veil Nebula (a supernova remnant), single 5 min exposure on my 80mm travel scope. Ionized hydrogen (red) and oxygen (green) make a beautiful arc, part of a broader formation called the Cygnus Loop. One of my favs! 🔭🧪
Paul Macklin
@mathcancer.bsky.social
Professor of Intelligent Systems Engineering at Indiana University School of Informatics, Computing and Engineering • mathematical biologist • multicellular systems & cancer with PhysiCell • OpenSource • astrophotography Web: http://MathCancer.org
I just heard the official news: the Indiana Commission for Higher Education has approved IU Luddy's new B.S. in Biomedical Engineering! Way to go, everyone! This was my last major project as associate dean (see link below), so I'm thrilled to see the official green light! (1/2) #AcademicLeadership
My Last day as Associate Dean
Today is my last day as Associate Dean for Undergraduate Education at the Indiana University Luddy School of Informatics, Computing, and Engineering at Indiana University Bloomington. As my three year...
linkedin.com
1. We—@eduede.bsky.social, @mjcrockett.bsky.social, Kevin Gross, and I—have a new preprint on the arXiv today, based on ideas that emerged during an @sfiscience.bsky.social workshop in November 2024: The unintended consequences of large language models as a labor-augmenting technology in science.
The unintended consequences of large language models as a labor-augmenting technology in science
As a labor-augmenting technology, large language models (LLMs) have the potential to accelerate scientific activity across the research pipeline. But even if LLMs perform on par with human experts at ...
arxiv.org
In just ten minutes at the airport I’ve seen multiple Purdue ads. Multiple Taylor U. ads. Multiple Ivy Tech ads. Zero from IU. Pam pays her comms + marketing team multiple millions of dollars a year. To apparently choose to lose the race in a very visible location.
1/11 In late June 2026, a paper in Nature by Labini & Galoppo using data from the DESI project claimed to have found anisotropy (directional differences) in the #Universe on scales up to 1 gigaparsec (about 3.26 billion ly). 🔭 This would have challenged the standard ΛCDM model.⚛️ 🧪 #cosmology
This is huge! Triple Negative Breast Cancers (TNBCs) are aggressive & disproportionately strike younger women. Historically, TNBCs have limited treatment options. Trodelvy, which targets Trop-2 is now approved in the US for first line treatment of metastatic TNBC. 🧪 www.gilead.com/news/news-de...
The OMB rule should be the most talked about topic right now. Why? It codifies political interference in all fundamental aspects of scientific discovery. We would not have Wegovy, Ozempic, Herceptin, Tamoxifen or other drugs if science was censored. 🧪 27unihted.substack.com/p/how-to-sto...
Political control of NIH is about to become the law, but you can stop it
Read our short guide on the "Regulation for Federal Financial Assistance," learn how you can leave an effective comment, and other actions you can take
27unihted.substack.com
Wow! Blast from the past! While cleaning some boxes, I found a 1999 letter admitting me to the PhD program at the Cornell Center for Applied Mathematics, signed by none other than @stevenstrogatz.com as Director of Graduate Studies. I stupidly didn’t take them up on their offer to visit. :-/
Today is my last day as Associate Dean for Undergraduate Education at IU Luddy. As my three years draw to a close, I find myself with more thoughts than the character limit, so I wrote a short article. :-) #assdean #leadership #academia #education www.linkedin.com/pulse/my-las...
My Last day as Associate Dean
Today is my last day as Associate Dean for Undergraduate Education at the Indiana University Luddy School of Informatics, Computing, and Engineering at Indiana University Bloomington. As my three year...
linkedin.com
It was really fun to talk with eisensteinium.bsky.social for his piece in @nature.com about #VirtualCells and #VirtualTissues. Thanks for including #PhysiCell and joint work with @fertiglab.bsky.social & others! Please do give this terrific piece a read! www.nature.com/articles/d41...
‘Virtual cells’ aim to turn raw data into predictive models of biology
Simulations of biological systems could transform biomedical research, but researchers are still learning how to reproduce life’s complexity without drowning in data.
nature.com
"Everything" is one of the comics that will be included in the "Parenting " SMBC comic collection that is currently available on Kickstarter! KICKSTARTER ◆ www.kickstarter.com/projects/wei...
Congress passed a budget that rejected cuts to the #NIH, NSF, NASA, DOE. However, OMB (i.e. Russel Vought) stalled in releasing funds. As of Mar 24, the NIH has only rewarded 15% of its $47B budget. PhD programs are shrinking. China & India will dominate. 🧪 universitybusiness.com/research-cut...
Research cuts are now having a chilling effect on academia
Universities are feeling the effects of delayed research funding even after lawmakers rejected deep proposed cuts in fiscal year 2026.
universitybusiness.com
Timeline cleanse! Is there anything better than a corgi in a car?
My thoughts on Director Bhattacharya's Fireside Chat at the NAM workshop (a long 🧵) Overall (1) He clarified what he said that NIH is doing with regard to improving replication. While these are concrete steps, they seem either naive or dependent of unproven technology. Time will tell. 1/30
The UK/Europe edition of The Edge of Space-Time has landed in New Hampshire!! It's very pretty!! Out May 7 from @canongate.co.uk -- preorder now! And yes, North Americans, you can collect them all :-D 💙📚 buythebook.online/edge-of-spac...
Testing a new Zwo AM3N mount—part of an 80mm APO travel setup. So far, guiding looks good! For reference, I have a ~2”/px imaging scale. 🔭
🎉 The SMB #MathOnco Subgroup is launching its inaugural Early Career Awards! Grad student or postdoc presenting at #ECMTB2026 / #SMB2026 in Graz? Apply by April 30th! 🔗 smb.org/call-for-award-nominations/
Mathematical Oncology - Call for Award Nominations
smb.org
OpenAI announces ChatGPT is now at the level of real scientific reviewers, “It just tells you to do single-cell RNAseq in response to every query” says Sam Altman
Continued 2: EF: Intuitive modeling of cell dynamics in tumor immunotherapy. With @mathcancer.bsky.social #STAGE https://www.cell.com/cell/fulltext/S0092-8674(25)00750-0
Now: @fertiglab.bsky.social (EF): Forecasting tumor-immune dynamics in pancreatic cancer #STAGE
William Oughtred, author of the most influential maths book in 17th C England & inventor of the sliderule, was born 5 March 1575 #histsci thonyc.wordpress.com/2014/03/05/s...
Sliding to mathematical fame.
William Oughtred born on the 5th March 1575, who Newton regarded along with Christopher Wren and John Wallis as one of the three best seventeenth-century English mathematicians, was the epitome of …
thonyc.wordpress.com
Meet three scientists who said no to Epstein. The warning signs included a web search, a mother’s doubts, and inklings of a “sexist attitude” www.science.org/content/arti...
Meet three scientists who said no to Epstein
The warning signs included a web search, a mother’s doubts, and inklings of a “sexist attitude”
science.org
Indeed. New grants are not getting funded, already funded grants are not getting paid, and non-competitive renewals are being held up. Focusing on the top line budget, instead of looking at what is really happening on “the ground” is deeply misguided.
Max Kozlov@maxkozlov.bsky.social · 5mo agoCongress rejected massive cuts to US science budgets for 2026, but much of the money still isn’t flowing to researchers. The culprit? The White House Office of Management and Budget (OMB) is quietly slow-walking the release of funds. 🧵👇
Interested in doing a PhD in tumor mechanobiology? At Université Paris-Saclay, the upcoming PhD selection process is open, and I’m looking to put forward a candidate to join my lab. If you’re excited about uncovering how mechanical signals regulate tumor progression, please get in touch!
The first version of FigTree was released nearly 20 years ago and it is still widely used (including by me). But there are currently 85 issues on the GitHub repo (github.com/rambaut/figt...) and some of them I don’t really like the look of.
rambaut/figtree
Automatically exported from code.google.com/p/figtree - rambaut/figtree
github.com
Can astronomical imaging be more sensitive, with no additional observations? Guo et al. apply machine learning to the co-addition (stacking) of multiple exposures. For stacks of 8 JWST NIRCam exposures, the detection limit improves by 1 magnitude. ☄️🔭 #astrocode www.science.org/doi/10.1126/...
Continue to stay where you are, Bloomington. Behemoth of a supercell. Rotation should be directly over downtown now (7:11 pm)
