𝗛𝗼𝘄 𝘁𝗼 𝘁𝗵𝗶𝗻𝗸 𝗼𝗳 𝗯𝗿𝗮𝗶𝗻 𝗺𝗮𝗽𝘀? It seems like a boring visualization change but quite important! fMRI maps have been thresholded for 3+ decades so as to emphasize peaks of activation. This paper argues for a different approach. rdcu.be/B4tikBETdQZa
Paul Taylor
@afni-pt.bsky.social
Brain imaging methods at SSCC/NIMH/NIH, working in C/Python/tcsh, some astrophysics in world line, programming/processing lecturer at AIMS. All views my own.
Have you ever felt like something was missing from your #fmri results? Have you been worried about potential reproducibility issues? Well, this new @natmethods.nature.com article with 40+ coauthors shows how the simple change to transparent thresholding helps both. Go Figure! rdcu.be/B4tikBETdQZa
We are hiring for a tenure track faculty position! Our Institute, part of Jefferson Moss-Magee Rehabilitation and Thomas Jefferson University, is seeking applicants with experience conducting research in human translational neuroscience & neurorehabilitation. https://ow.ly/KRzP50ZiKqh
Newest contribution to the AFNI Codex (Code Examples), linking papers and scripts/cmds that were used. Thanks to the amazing @storrisi.bsky.social & LL Chao for this latest work. We hope this and others help users with ideas and examples for their own projects: afni.nimh.nih.gov/pub/dist/doc...
14.2. FMRI Codex — AFNI, SUMA and FATCAT: v25.2.00
afni.nimh.nih.gov
Job ad (2/2): data scientist in the AFNI group (SSCC, NIMH, NIH, USA). FMRI/MRI methods dev, software design, statistics, analysis, data viz, quality control, machine learning and more! Please see: discuss.afni.nimh.nih.gov/t/job-ad-dat... I am happy to chat at OHBM+Brainhack. Please share!
Job ad (1/2): Postdoc fellowship in the AFNI group (SSCC, NIMH, NIH, USA). FMRI/MRI methods dev, software design, statistics, analysis, data viz, quality control, machine learning and more! Please see: discuss.afni.nimh.nih.gov/t/job-ad-pos... I am happy to chat at OHBM+Brainhack. Please share!
22 years is just about half a lifetime for some. Congratulations to Arsenal fans everywhere---happy times in North London and radiating outward. Now we turn our attention to May 30. #COYG
Looking forward to this!
🔦 Speaker Spotlight: Eduardo A. Garza-Villarreal, M.D., Ph.D. 🎤 Understanding Neuromodulation in Substance Use Disorders: A Bidirectional, Cross-Species MRI Approach 🧠 Exploring substance use disorders through cross-species MRI research bridging neurobiology and psychiatry. 🔗 tinyurl.com/ynzhsxvy
Thanks very much @mossresearch.bsky.social and Andrew Persichetti there for hosting @gangchen6.bsky.social , Justin Rajendra and myself for an AFNI Bootcamp last week! Awesome group of attendees. We had a great few days of FMRI details, concepts, practice and discussions.
Thanks to all who attended the AFNI Bootcamp in Philly! We enjoyed hosting the 3-day intensive course that brought together clinicians & scientists to learn to process raw MRI data from start to finish w/ expert guidance from the AFNI team of the Scientific & Statistical Computing Core in the NIMH.
Does anyone know the registration cost for the Brainhack event at OHBM-2026? I can't find any details for it on the website.
Does anyone know the registration cost for the Brainhack event at OHBM-2026? I can't find any details for it on the website.
Want to learn about FMRI visualization, processing and group analysis? Join us for the next AFNI Bootcamp (Jan. 27-29, 2026) for a fun few days of theory and interactive practicals. Details+registration for this virtual course: afni.nimh.nih.gov/bootcamp
This is a really nice way forward for #fmri and other neuroimaging analyses, now at the voxelwise level! Great ideas, math and implementation by @gangchen6.bsky.social, Yuan Zhong and Jian Kang. Oh, and it even has a fun acronym, too: SIMBA -> Scalable Image Modeling using a Bayesian Approach
And the next step? Full voxel-level modeling. Recent numerical advances cracked the scalability barrier. Voxel-level hierarchical modeling is now feasible, revealing just how punishing traditional multiple-comparison adjustments really are. arxiv.org/abs/2511.12825
New AFNI Academy playlist! This tutorial presents afni_proc.py's quality control HTML for single subject FMRI. The APQC HTML has systematic views of data and useful derived quantities. Users can instantly rate, comment and query the fully processed subject data. www.youtube.com/watch?v=hD9z...
Thanks, @gangchen6.bsky.social for leading the charge on pointing out and detailing several really important things to think about at the heart of FMRI studies and interpretation.
Thanks to Zhengchen Cai, @kordinglab.bsky.social, Tom Liu, Josh Faskowitz, @fmri-today.bsky.social, Bharat Biswal, and @afni-pt.bsky.social for fueling this ride and helping turn it into a commentary.
Announcing the next AFNI Bootcamp: Sep 23-25, 2025. Free, open & virtual. This "Part 1" will focus on basic visualization and single subject FMRI processing, including discussions of alignment, templates, regression, ROIs and quality control. Details & registration: afni.nimh.nih.gov/bootcamp
AFNI Bootcamp: Sep. 23-25, 2025 | afni.nimh.nih.gov
afni.nimh.nih.gov
If you’d like to write a commentary to accompany our new article arguing for a rethinking of how we approach understanding visual function in occipitotemporal cortex, now is your chance!
Our target discussion article out in Cognitive Neuroscience! It will be followed by peer commentary and our responses. If you would like to write a commentary, please reach out to the journal! 1/18 www.tandfonline.com/doi/full/10.... @cibaker.bsky.social @susanwardle.bsky.social
Cool work, and particularly after some recent discussions at OHBM, it is really nice to see all of transparent threshold, beta-weight overlay coloration and two-tailed tests used together in the results reporting. Helps me (and maybe others) see the whole picture clearly.
Excited to ✨share✨ that our paper on ✨sharing✨ is published! Across 3 studies that build on one another, we show that perceived alignment with one's peers increases the likelihood of information sharing. www.nature.com/articles/s41...
Looking forward to #OHBM2025 in Brisbane next week! My lab is recruiting a postdoc & neuroimaging analyst/developer to support our NIH funded work in fMRI-based Alzheimer's biomarker development (NIA R01AG083919). Email or DM if you want to meet up in Brisbane! www.statmindlab.com/join-us
Home
What can we do with functional MRI data? For many years, fMRI has been used to discover population-level patterns of brain function, organization and connectivity, and to understand differences in t...
statmindlab.com
When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...
The history and future of resting-state functional magnetic resonance imaging - Nature
This Review provides an overview of the history of resting-state functional MRI research, which has helped to reveal the spatiotemporal organization of the brain, and discusses how it can contribute f...
nature.com
**FMRI/neuroimaging folks** Quick reminder @ the next AFNI Bootcamp: May 28-30, 2025. Learn through interactive data analysis! Day 1-2: data viz, single subject analysis and QC. Day 3: statistics, results reporting and group analysis. Details, registration and schedule: afni.nimh.nih.gov/bootcamp
We are pleased to announce the next AFNI Bootcamp, May 28-30, 2025. First 2 days: data visualization, single subject analysis and QC. 3rd day: statistics, results reporting and group analysis. Please see here for details, registration link and preliminary schedule: afni.nimh.nih.gov/bootcamp
AFNI Bootcamp: May 28-30, 2025 | afni.nimh.nih.gov
afni.nimh.nih.gov
Who knew that breathing was so important? Well, at least in FMRI it is... Nice work by @brightmg.bsky.social & Co!
Breath hold fMRI is great for measuring CVR... *except when your participant or patient doesn't quite perform the task the way you'd like. Let's see if we can fix that! (Spoiler, it looks like we can, using the respiratory belt data to predict or fill in missing PETCO2 data!)
Nice work, @gangchen6.bsky.social !
Should statistics respect science more? Our third speaker Gang Chen (@gangchen6.bsky.social) argues that strict adherence to statistical conventions may obscure rather than clarify, and suggest ways in which rethink about how we model our data and report our results:
"Highlight, don't hide" @gangchen6.bsky.social makes an impassioned argument that thresholding (reflective of a "binary" yes/no approach to analysis) holds back our science, making it less transparent and less reproducible. Instead, be a facilitator - share uncertainty and evidence! #SANS2025
The result of a large (42 authors!) collaboration: "Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation" arxiv.org/abs/2504.07824 TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
Excellent folks to work with!
Likely hiring one postbac trainee for @fmri-today.bsky.social's Section on Functional Imaging Methods. Give the relatively later start time for the search, I'm not yet sure how quickly this search will happen. If you are interested, apply and reach out ASAP. fim.nimh.nih.gov