Amanda Bretman

@amandabretman.bsky.social

Professor of Behavioural Ecology, University of Leeds, UK. The biology of sex and social environments, and Thermal Fertility Limits, mainly of fruit flies.

Quick plug for our new resource, the Drosophila Species Stock Exchange. This is a database and mailing list that documents species currently in culture and the labs holding them. If you want to know more or sign up then please get in touch. See attached for more info and please share!

Bild

New preprint! We looked at age-specific preferences for protein and carbohydrate in males and females, where females lay their eggs vs what larvae choose& do best on, & found unexpected parental age effects. With @eivimeycook.bsky.social @alexeimaklakov.bsky.social Wilfried Haerty& Tracey Chapman

EcoEvoRxiv@ecoevorxiv.bsky.social · 5d ago

Age-related shifts in dietary and oviposition preferences and steep costs of modest parental ageing in Drosophila melanogaster doi.org/10.32942/X26...

1/3 Refugee Week is a moment to reflect on the role universities play in building cultures of welcome and belonging. At Leeds our University of Sanctuary status recognises ongoing work to support students and academics forced to flee, and the vital perspectives they bring to research + scholarship.

🌍🔥🦋 Global collaboration: Ontogenetic Thermal Fertility Limits! We're bringing together researchers to understand how temperature affects fertility across life stages in a warming world. If you work on #insects #fertility, we'd love for you to join us. www.thermalecologyalliance.org #scicommUU26

TEA - Thermal Ecology Alliance

A global collaborative initiative assessing, communicating, and mitigating the impacts of extreme temperature events on biodiversity.

thermalecologyalliance.org

New paper accepted in Proc B! 🎉 We disentangled how heatwaves affect maternal egg care in earwigs. We found that mothers adjust care depending on both their own heat stress and the stress of their eggs, but these effects act independently rather than interactively. doi.org/10.1098/rspb...

Heat stress disrupts maternal care through independent effects on mothers and eggs

Abstract. Parental care typically protects offspring from environmental stress. Yet, it remains unclear whether this protection arises from stress effects

doi.org

Latest paper. We studied ATF4 in ageing in the fly. We find in contrast to previous suggestions that ATF4 suppression rather than activation extends lifespan. The study was largely conducted in an MSc project by Miriam Götz who showed an exceptional drive for science. www.pnas.org/doi/10.1073/...

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

pnas.org

Safe to say that we are very excited about this here at ESEB! Huge thanks to Brian Golding for entrusting us with the fantastic service that you have created and curated for the years! Follow @evoldir.bsky.social

EvolDir@evoldir.bsky.social · 4mo ago

📣 EvolDir is now managed by @eseb.bsky.social! We are delighted to be taking the reins and express our gratitude to both Brian Golding who began this service to the community in the mid-1980s and to @rdmpage.bsky.social who ran this account until now 👏 You can now find evoldir here: evoldir.net

Dietary restriction shapes intergenerational ribosome abundance and early growth of Caenorhabditis elegans offspring @PLOSBiology.org

Dietary restriction shapes intergenerational ribosome abundance and early growth of Caenorhabditis elegans offspring

by Sigma Pradhan, Klement Stojanovski, Ferdinand Dellemann, Sacha Psalmon, Joel Tuomaala, Nicholas E. Stroustrup, Benjamin D. Towbin Cells adjust their proteome to their environment. Most prominently, ribosome expression often scales near linearly with the cellular growth rate to provide sufficient translational capacity while preventing metabolically wasteful ribosomal excess. In microbes, such proteome adjustments can passively perpetuate through symmetric cell division. However, in animals, a passive propagation is hindered by the separation between soma and germline. This separation raises the question whether the proteome of animals is reset at every generation or can be propagated from parent to offspring across this barrier. We addressed this question for the intergenerational effects of dietary restriction in Caenorhabditis elegans, combining proteomics and live imaging. Under ad libitum feeding, the offspring of dietarily restricted mothers grew more slowly than progeny of well-fed mothers. However, this growth disparity was attenuated when mTORC1 signaling in the progeny was inhibited, creating conditions in which the protein-synthesis capacity at hatching is less limiting. Maternal inhibition of mTORC1 signaling, either ubiquitously or specifically in the pharynx, similarly reduced growth and ribosomal protein levels in offspring, whereas other growth-reducing perturbations, such as reduced insulin signaling or mTORC1 inhibition in the epidermis, did not reduce progeny ribosomal protein levels. We conclude that maternal physiology shapes ribosomal protein provisioning across the soma-germline boundary, thereby modulating early offspring growth in accordance with post-hatching ribosome demand.

dlvr.it

🔥 We'll soon be advertising a 2-year Postdoctoral Research Fellow position at UCL, focusing on insect single-cell mitochondrial genomics. 🔥 More details coming soon. Feel free to get in touch in this sounds fun or share with anyone who might be interested.