Very excited to see our paper, led by @amilangscience.bsky.social, out today in @pnas.org! This one was a true adventure, filled with surprises at every turn. “Erythroid precursors regulate local oxygen tension and repair outcomes in the bone marrow niche.” www.pnas.org/eprint/NJ8XC...

Erythroid precursors regulate local oxygen tension and repair outcomes in the bone marrow niche | PNAS

Oxygen tension dynamically regulates stem cell fate and tissue regeneration, yet how local oxygen availability is controlled within the bone marrow...

pnas.org

Fuller Albright Award Joel Boerckel, Ph.D., University of Pennsylvania, United States

Such a pleasure to contribute to this nice session 🧫🦴🔬 thanks for the shout out @ricgottardi.bsky.social so glad for your contribution to the project I just highlighted. Looking forward to amazing days in #Davos at #eors2025 🩻🎉

Riccardo Gottardi@ricgottardi.bsky.social · last yr.

Go @amilangscience.bsky.social! Great talk at #eors2025 from in vitro models to in vivo and back in vitro to study fracture healing and the role of vasculature! @umich.edu @jboerckel.bsky.social

Yesterday was an awesome day in science, with the 9th annual MSK Symposium for the MiMHC @umich.edu! Great talks from faculty and trainees, featuring work from across Southeast Michigan🦷🦴 🎉Lavi won the Speakers Choice poster award 💪Alayna Loiselle was the keynote speaker @urochester.bsky.social

Our paper, led by Chris Panebianco (@cpane94.bsky.social) is out today at Developmental Dynamics! "Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod." anatomypubs.onlinelibrary.wiley.com/doi/10.1002/...

Joel Boerckel@jboerckel.bsky.social · 2y ago

Best way to end 2024. Our latest preprint, from @cpane94, is out today @biorxivpreprint!! Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod. biorxiv.org/content/10.110… A paper thread (complete with morphogenesis, mechanobiology, and murder):

📣 Registration is open for the VII. MuSkITYR Symposium, Nov 3–4, 2025 in Dresden! Join us for 2 days of musculoskeletal research exchange with keynotes by Martina Rauner & Stefan Zwingenberger.🎓 Young researchers are invited to submit abstracts! muskityrs.com/anmeldung-dr... @tudresden.bsky.social

Excited to share the latest chapter of our work on fat-joint interorgan crosstalk in knee OA, featuring the role of complement factor D secreted by fat in knee pain. Link here: bit.ly/42Og5hJ Thanks to @farsh-g.bsky.social for all of your support - @thehopefulscie1.bsky.social and all coauthors!

📰 So excited that this paper is finally published 🤩🥳 check it out and enjoy a great ride with a lot of different methods 🦴🔬🐀🦖🧫

Joel Boerckel@jboerckel.bsky.social · last yr.

Annemarie’s latest paper is out today! CYR61 delivery promotes angiogenesis during bone fracture repair. www.nature.com/articles/s41... @amilangscience.bsky.social @madhura0327.bsky.social @cpane94.bsky.social @eseidlscience.bsky.social @ricgottardi.bsky.social et al.

JOIN US for our next ORS PCM Webinar 🐁🐀🦖👩‍⚕️ don't forget to sign up 👇

Orthopaedic Research Society@orssociety.bsky.social · last yr.

Join the Preclinical Models Section for #WebinarWednesday on April 9 at 12 PM CT! Dr. Monica Sentmanat will provide a foundational understanding and practice guidance on the do’s and don’ts, common challenges, and more in transgenic mouse models. Register now: ors.memberclicks.net/pcm040925...

Save the date! The VII. MuSkITYR Symposium will be held November 3–4, 2025 in Dresden, Germany. Let’s come together again to advance musculoskeletal research and build on the momentum we’ve created. Stay tuned for more details! #boneresearch #cartilageresearch #bonehealth #orthobluesky

I don’t have words to express how grateful I am for this crew. So glad I did my PhD here! So much love to every single person in this photo for celebrating this milestone with me! ❤️❤️

@amilangscience.bsky.social’s talk was so cool!! She is also recruiting for her lab- and she is amazing to work with!!

ORS ISFR@isfrfractures.bsky.social · 2y ago

Did you know bone fractures can trigger *local erythropoiesis* to prevent hypoxia at the fracture site? 🦴✨ @amilangscience.bsky.social is diving into the mechanism in North 221C! #ISFR #ORS #Innovation

Sci1: @amilangscience.bsky.social podium was a highlight for me: Current thinking is that when a bone fractures, blood vessel rupture causes hypoxia at the fracture site. Lang et al. showed that the early fracture site is not hypoxic. www.biorxiv.org/content/10.1...

Excited for #ORS2025 and super proud of this group who will be presenting their work! 🙌🏻 @madhura0327.bsky.social @gkotsaris90.bsky.social @eseidlscience.bsky.social @amilangscience.bsky.social @cpane94.bsky.social ht @cpane94.bsky.social for the slide!

So proud of our latest work 😍🦴🩸 This project was a rollercoaster 🎢, but I loved every moment of it. Huge thanks to all amazing collaboration partners at UPenn 👩‍🔬🧑‍💻👨‍🔬🧑‍💼 Don’t miss the perfect thread by @jboerckel.bsky.social breaking it all down 👇Let us know what you think💡 Funded by #MSCA #Postdoc

Joel Boerckel@jboerckel.bsky.social · 2y ago

I am thrilled to release our latest preprint from @amilangscience.bsky.social, out today @ biorxivpreprint! Local erythropoiesis directs oxygen availability in bone fracture repair. biorxiv.org/cgi/content/... A paper thread:

My first week is in the books & I’m thrilled to announce that I’ve joined UMich Orthopaedic Surgery as an Assistant Prof 🦴🎉 I’m beyond excited for this new chapter chasing unsolved research questions 🥳👩‍🔬 Special thanks to the best mentor ever @jboerckel.bsky.social 🙏 Here’s to what’s ahead #GoBlue💛💙