RNA-seq tells us how much RNA is present in the cell. But to understand gene regulation, we need to easily measure the synthesis and decay rates driving this abundance. We introduce AIR-seq: analog intrinsic recoding sequencing. (1/6) www.biorxiv.org/content/10.6...

Analog intrinsic recoding measures RNA dynamics without chemical conversion

Steady-state RNA abundance measurements mask the synthesis and decay rates that shape gene expression. Analog intrinsic recoding sequencing (AIR-seq) repurposes the base-pairing properties of N4-hydro...

biorxiv.org

I am delighted to share that my newest manuscript and the first of my postdoc in the Marqusee and Bustamante labs, “A detailed molecular picture of protein folding during active translation”, is now on the BioRXiv! (1/n) www.biorxiv.org/content/10.6...

A detailed molecular picture of protein folding during active translation

All proteins can begin to fold on the ribosome, and many proteins critically rely on co-translational folding to attain their native conformation. The molecular details underlying this crucial process...

biorxiv.org

Would love to see you at my talk and/or poster at BPS this week!

Marqusee Lab@marquseelab.bsky.social · 5mo ago

Amir Bitran is co chairing the protein folding and stability platform tomorrow (4 pm rooms 201-203) and giving a platform talk as part of that session at 4:45 pm

Had a blast at the protein folding GRC, my absolute favorite meeting. It feels like a family reunion, and always rejuvenates my passion for science. Can't wait for 2028!

Marqusee Lab@marquseelab.bsky.social · 7mo ago

And congrats to Amir Bitran @amirbitran.bsky.social for receiving a poster prize, and to lab alum Sara Volz @saravolz.bsky.social for receiving both a poster prize AND best talk prize at the GRS!

The Marqusee lab is at the 2026 protein folding Gordon Research seminar + conference! Amir will be giving a 10 min talk at the GRS today, while Eva will give a 10 min talk at the GRC on Tuesday! Susan will serve as a panelist on today's career panel at the GRS!

Thrilled to be giving a talk at the University of Chile tomorrow on my research (in spanish/spanglish)! Feel free to scan the QR code below, or contact me for a link if you're interested in joining!

Really excited to be giving a seminar next week at @purduechemistry.bsky.social

Thrilled to be part of the Everyday Scientist project run by the awesome JCC fellowship--a community I'm honored to be a part of. Check out this short video on my research and spread the word about how awesome science can be!

Jane Coffin Childs Fund for Medical Research@jcchildsfund.bsky.social · 9mo ago

Proteins are the best, and so is Amir! Check out his video to learn more about protein folding, misfolding, and the implications: www.youtube.com/shorts/K9At4...

Really thrilled to share my latest co-first author publication in Science Advances, the culmination of a project from my PhD with Eugene Shakhnovich and a wonderful collaboration with the lab of Marina Rodnina www.science.org/doi/full/10....

Cotranslational protein folding through non-native structural intermediates

Early folding intermediates form via non-native contacts and are reshaped by chaperones during protein synthesis on the ribosome.

science.org

Are you from one of these states? Then we need your help to save American science! The Senate Appropriations Committee will be marking up the President's Budget Request for science on Wednesday. People have been saying the proposed cuts "decimated" US science, but that's wrong: they are apocalyptic

Lovely article from our colleague Kseniia Petrova, who has been wrongfully imprisoned for months: www.nytimes.com/2025/05/13/o...

Opinion | The Science I Would Be Doing if I Weren’t in ICE Detention

nytimes.com

Such an honor to give a talk at the annual @jcchildsfund.bsky.social retreat as a third year (!!) fellow. Thank you to the JCC for the fantastic support and lifelong community

Jane Coffin Childs Fund for Medical Research@jcchildsfund.bsky.social · last yr.

Dr. Amir Bitran @amirbitran.bsky.social from Dr. Susan Marqusee and Dr. Carlos Bustamante labs at UC Berkeley is telling us about his research on cotranslational protein folding. Dr. Bitran is developing a sensitive technique to probe the dynamic states of proteins during the earliest folding 9/

At the Stand up for science march, San Francisco

Dear all , Here is a call of more than 80 Israeli musicians re the situation in Israel and Palestine. We will be grateful for sharing over social media widley. www.facebook.com/permalink.ph...

Here's a very important update from the AAMC (Association of American Medical Colleges) on the proposed cuts to NIH Indirect costs: "Every year since 2017, the annual spending bill that funds NIH has included language prohibiting the Administration from making changes to F&A cost rates" 1/2 🧪

Extremely disappointed to see HHMI decide to kill their Inclusive Excellence program, including terminating the current IE3 awards to over a hundred institutions effective this year in the middle of a 6-year grant. I was hoping HHMI (and other private funders) would continue to lead the way.