It might be just me but slack messages from bots easily slip my mind

Geese are insane: Example #2,987,304

Stem Cell & Developmental Biology Early Career Symposium was one of the greatest event I've ever attended. Good scientific input, meeting new people, sharing excitement/failure. I am feeling so lucky that this was held at right across the street I walk everyday!

One of the best moments in conferences is to meet someone who reached to the same problem independently🤝

www.biorxiv.org/content/10.6... In vivo reconstruction of the cell lineage history of a developing mouse with DNA Typewriter, from zygote to late organogenesis 😍

The elephant in the room: impact factor 🐘 @jamesbriscoe.bsky.social and @amjeve.uk openly discuss their views on the impact factor and how the field of developmental biology is perceived through its lens. thenode.biologists.com/the-elephant... #DevBio #AcademicPublishing #ImpactFactor

Xenophagocytosis blockade enhances interspecies chimerism: Cell www.cell.com/cell/fulltex... Great to see this on Cell!

Xenophagocytosis blockade enhances interspecies chimerism

Host macrophages limit interspecies chimerism via xenophagocytosis, whereby stressed donor cells expose phosphatidylserine as an “eat-me” signal. Blocking xenophagocytosis successfully enhances donor ...

cell.com

Now online! Xenophagocytosis blockade enhances interspecies chimerism

Xenophagocytosis blockade enhances interspecies chimerism

Host macrophages limit interspecies chimerism via xenophagocytosis, whereby stressed donor cells expose phosphatidylserine as an “eat-me” signal. Blocking xenophagocytosis successfully enhances donor chimerism and enables efficient exogenic organogenesis.

dlvr.it

Opus4.8 keeps failing to call list_events from Gcal MCP since yesterday. Sonnet4.6, Opus4.6, Opus4.7 can call it. Weird! Might be related to the Fable's issue?

This visual timer is by far the best buy of the year for my setup

1/ Thrilled to share our latest: an exciting collaboration across the @jshendure.bsky.social, @leastarita.bsky.social, @nobuhamazaki.bsky.social and @dschweppe.bsky.social labs! 🧵 below- #SystemsBiology #SCBEM #MultiOmics #Gastruloids www.nature.com/articles/s41...

The proteomic landscape and temporal dynamics of human and mouse gastruloid development - Nature Cell Biology

Garge et al. use experimentally matched mass spectrometry and RNA-sequencing to quantify proteins, phosphosites and transcripts across four key stages of human and mouse gastruloid development.

nature.com

Happy to see our new paper on benchmarking RNA/protein dynamics in human and mouse gastruloids in Nature Cell Biology! 🎉 www.nature.com/articles/s41...

The proteomic landscape and temporal dynamics of human and mouse gastruloid development - Nature Cell Biology

Garge et al. use experimentally matched mass spectrometry and RNA-sequencing to quantify proteins, phosphosites and transcripts across four key stages of human and mouse gastruloid development.

nature.com

Inhibition of MAFB and PI3K/AKT Signaling for Hereditary FSGS with Multicentric Carpotarsal Osteolysis : Journal of the American Society of Nephrology journals.lww.com/jasn/abstrac...

0.33g mitigates muscle atrophy while 0.67g preserves muscle function and myofiber type composition in mice during spaceflight - goo.gl/scholar/MGaj1S Congrats for the team!!

William Foege has died. He was a central architect of smallpox eradication, pioneering surveillance-driven ring vaccination when vaccine supply was limited. That strategy helped eliminate the deadliest human pathogen we’ve ever known. www.nytimes.com/2026/01/24/u...

William H. Foege, Key Figure in the Eradication of Smallpox, Dies at 89

nytimes.com

Please 🔁 My group at UBC received an allocation from the school to apply for the Canada Impact+ Training Awards (postdoc). Everything is moving fast but please email me in 48 hours with a CV if you are outside Canada and interested😎 Yachie lab: yachie-lab.org sshrc-crsh.canada.ca/en/funding/o...

It's my honor to be selected as one of the inaugural SeaBridge Fellows!👏 seabridge.uw.edu/2026/01/22/s...

I never knew the title of the original BLAST paper was 'A Greedy Algorithm for Aligning DNA Sequences'. I just came across it and it's too cool!🤯 www.liebertpub.com/doi/10.1089/...

The WRF has awarded three-year postdoctoral fellowships to a new cohort of 12 early-career researchers who will pursue innovative, high-impact projects. 📝 See the full list including Drs. Winston Dredge, Nastacia Goodwin, Stefany Cruz, and Nathaniel Ritz: https://bit.ly/3L0DhEM

www.biorxiv.org/content/10.6... Extremely fine tuned. genuinely admiring!

Human trunk embryoids with patterned anterior-posterior and dorsal-ventral body axes: utility for understanding human development and disease

Human embryoid models enable mechanistic studies of development and disease. We generated trunk embryoids from human pluripotent stem cells that recapitulate posterior trunk formation at Carnegie stag...

biorxiv.org

Favorite fidget toy

Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...

Modelling co-development between the somites and neural tube in human trunk-like structures - Nature Cell Biology

Makwana, Tilley et al. generate human stem cell-based trunk-like structures approximating Carnegie stage 13–14 of development. They use them to model and study the development of the thoracic and lumbar trunk.

nature.com

when we say we want more streets to be pedestrianized, this is what we mean

Congratulations to Karel Svoboda and @jshendure.bsky.social on their election to the National Academy of Medicine (@nam.edu)! Election to the Academy is one of the highest honors in health and medicine. #NAMmtg More on their journeys to this achievement: alleninstitute.org/news/karel-s...

Karel Svoboda and Jay Shendure elected to National Academy of Medicine

The honor recognizes leaders who have demonstrated outstanding achievement and made lasting contributions to the advancement of the medical sciences, health care, and public health

alleninstitute.org

www.biorxiv.org/content/10.1... Simplified In Vitro Generation of Human Gastruloids for Modelling Early Development

Simplified In Vitro Generation of Human Gastruloids for Modelling Early Development

The purpose of this study was to optimize the efficiency and cost of human gastruloid formation by testing and adjusting individual parameters using as examples two distinct human pluripotent stem cel...

biorxiv.org

Plasmidsaurus's 50$ RNA-seq is just amazing. I won't do qPCRs anymore

🦖 Something HUGE just hatched. Plasmidsaurus now offers RNA sequencing for gene expression analysis: • As fast as 3 day turnaround • $50/sample for academia, $80 for industry • Up to ~10M unique transcript 3’ end reads per sample • Interactive results Explore Plasmidsaurus RNA-Seq today.

Happy Mid-Autumn Festival!!🥮🎑🌕 I love mooncakes so much

Twenty-four years ago today, our paper “A forkhead-domain gene is mutated in a severe speech and language disorder” was published: www.nature.com/articles/350.... A personal thread about the ups & downs of the journey we took to get to that point....1/n 🗣️🧬🧪

Today in @nature.com, we present our work leveraging functional genomics and human blastoids to uncover a human-specific mechanism in preimplantation development driven by the endogenous retrovirus HERVK. Special thanks to the reviewers whose comments improved our manuscript a lot! rdcu.be/eI3tD

A human-specific regulatory mechanism revealed in a pre-implantation model

Nature - Genetic manipulation of blastoids reveals the role of recently emerged transposable elements and genes in human development.

rdcu.be