An international team of immunologists, clinicians, experimentalists, computational biologists, and engineers is building an Immune Digital Twin to transform human healthcare for immune-mediated diseases. #ImmunoSky #DigitalTwin 🧪
Arnau Montagud
@arnaumontagud.bsky.social
Tenured Researcher on Computational Systems Biology Institute for Integrative Systems Biology (@i2sysbio.bsky.social), @csic.es visitor at @bsc-cns.bsky.social, @alfonsovalencia.bsky.social team also at @arnaumontagud@fediscience.org
By Niarakis et al., including: @athinacp.bsky.social @eirini-tsirvouli.bsky.social @hasanbalci.bsky.social @ozanozisik.bsky.social @arnaumontagud.bsky.social @subbannayya.bsky.social @mkutmon.bsky.social Learn about their 5-year plan: www.immunoinformaticsjournal.com/article/S266...
Building Immune Digital Twins: An International and Transdisciplinary Community Effort
Digital twins, initially developed for industrial applications, are set to make significant advancements in medicine and healthcare. They have demonstrated promising potential for drug development and...
immunoinformaticsjournal.com
🚨 New in PNAS! 🧬 64% of disease co-occurrences can be explained by transcriptomic similarities. Comorbidities aren’t random—they have a molecular basis. Here’s how we found it 👇 (1/n) 🔗 doi.org/10.1073/pnas.2421060122 @alfonsovalencia.bsky.social
8/ Science already takes time, I hope to help make it worth it. Finally, terrified, we sent it to PNAS @pnas.org. After one round of review, reports came back: supportive. Positive. Accepted 🎉 🎉
1/ Everything that could go wrong in paper publishing… did. A story of patience, absurdity, and persistence 🌀 <1min From Alfonso Valencia’s lab and a very stubborn PhD student (me).
📢🔬 Abierto el plazo de inscripción para la II Jornada de Colaboración Público-Privada sobre Biología Computacional del #I2SysBio (@csic.es - @uv.es). 🗓 2 de septiembre www.i2sysbio.es/communicatio... ✍ Asistencia gratuita bajo previa inscripción. @moldrug.bsky.social @protoqsar.bsky.social
Registration is now open for the 2nd Public-Private Collaboration Workshop on Computational Biology at I2SysBio
<p><strong>The I2SysBio (CSIC-UV) will hold its second Public-Private Collaboration Workshop, a meeting that will bring together researchers, companies and organisations from the sector to discuss eme...
i2sysbio.es
Great opportunity to learn about computational systems biology modelling at the Wellcome Genome Campus in December. If you are interested in signing up, do so as soon as possible as the deadline is August 25!
Learn computational approaches to leverage biological networks for solving #biomedical disease challenges, at #ComputationalBiology25 course. 🗓️ Course dates: 7-12 December 2025 💸 Bursary support available Apply by 25 August 📩 📎 Find out more about sessions and instructors: bit.ly/4knNAi6
>> My conclusion: we do not have to demonstrate anything they have to change and adapt to the evolution of science / biology<< And computational biology is an essential component of biology. (It is ridiculous to have to say this in 2025)
Hiding Prompt Injections in Academic Papers Academic papers were found to contain hidden instructions to LLMs: It discovered such prompts in 17 articles, whose lead authors are affiliated with 14 institutions including Japan's Waseda University, South Korea's KAIST, China's Peking University and…
Hiding Prompt Injections in Academic Papers
Academic papers were found to contain hidden instructions to LLMs: It discovered such prompts in 17 articles, whose lead authors are affiliated with 14 institutions including Japan's Waseda University, South Korea's KAIST, China's Peking University and the National University of Singapore, as well as the University of Washington and Columbia University in the U.S. Most of the papers involve the field of computer science.
schneier.com
Original article: www.nature.com/articles/s41... 🧬🖥️ 👩🔬 🧪 The article explains how long-read transcriptomics enables the study of isoform expression, discovery of novel RNAs, gene annotation in understudied species, and differential expression between paternal and maternal chromosomes, etc.
Transcriptomics in the era of long-read sequencing - Nature Reviews Genetics
Advances in long-read sequencing are driving the implementation of these technologies for transcriptome profiling. The authors provide a comprehensive guide to long-read RNA sequencing, including expe...
nature.com
🦑🧪 I2SysBio researchers participate in Catalan Initiative for the Earth Biogenome Project @catbiogenoma.bsky.social of the Institut d'Estudis Catalans @iec.cat. Recently, Maria Dzunkova's @dzunkovam.bsky.social team published a paper in Ecology and Evolution 🌐 www.i2sysbio.es/communicatio... ⬇️
A more effective extraction method has been identified for obtaining high-quality DNA in less than ideal conditions
<p><strong>The ‘<a href="https://i2sysbio.es/groups/19/">Microbial Single-Cell Genomics</a>' research group at the Institute for Integrative Systems Biology I2SysBio (University of Valencia-...
i2sysbio.es
Two PhD positions to work on important and cool topics. And to make it even better, with some very nice and good people.
📢 Exciting news! We will soon open two PhD positions at @i2sysbio.bsky.social @csic.es, in research projects in collaboration with the @bsc-cns.bsky.social. Both are related to tools to simulate biological tissues. Here’s the description of the open positions. #PhDpositions #PhDOpportunities 👇
... it's dissolving humanity and culture and science... Without pause and time to think and reflect, and dedication to reach deeper into a problem, we only have the appearance of science. The incentives are all in the wrong side.
This tech accelerationism is training people to just do the appearance of work: a headline, art that looks almost normal from a distance, to complete things as fast as possible and move onto the next... it's dissolving humanity and culture at large
🚨 Two PhD positions available in the lab of @arnaumontagud.bsky.social in I2SysBio 🇪🇸. Both are related to simulations of biological tissues
📢 Exciting news! We will soon open two PhD positions at @i2sysbio.bsky.social @csic.es, in research projects in collaboration with the @bsc-cns.bsky.social. Both are related to tools to simulate biological tissues. Here’s the description of the open positions. #PhDpositions #PhDOpportunities 👇
📢 Exciting news! We will soon open two PhD positions at @i2sysbio.bsky.social @csic.es, in research projects in collaboration with the @bsc-cns.bsky.social. Both are related to tools to simulate biological tissues. Here’s the description of the open positions. #PhDpositions #PhDOpportunities 👇
Excited to see scPRINT published in @natcomms.nature.com ! scPRINT is a large cell model for the inference of gene networks pre-trained on 50Mcells with innovative pretraining tasks inspired from biology. Work led by @jkobject.com
I am super happy to annonce that after 9 months under review the first paper of my PhD: scPRINT is finally available on Nature Comms! 🎉🧬 www.nature.com/artic...
Alfred Fillol @alfredfisa.bsky.social, Arnau Montagud @arnaumontagud.bsky.social and Guillem Salazar @guillemsalazar.bsky.social are the three scientists who joined the Faculty of our institute I2SysBio last year. Follow them on Bluesky! More info on our website www.i2sysbio.es/communicatio... 🧪🦠💻🧬
⭐️We are hiring! ⭐️ We have 2 open postdoctoral positions in systems biology in Bordeaux, France. - 1️⃣ 2 years (+ 2) in metabolic modelling for cultivating uncultured bacteria. - 2️⃣ 18 months (+ 14 mo) in metabolic modelling of the rumen microbiome for methane reduction More info: cfrioux.github.io ⬇️
cfrioux.github.xn--io-ix0a
HubBCB-01 @CSIC.es. Impacto del microbioma respiratorio humano en la introducción de un nuevo patógeno. IP Mireia Coscolla (I2SYSBIO, Valencia) Cinco meses, cinco mensualidades de 600€, 20 horas/semana. Nota media de grado al menos 7. Si grado terminado, matriculado master bioinformática o similar.
Beca JAE-Intro ICU 2025 para realización TFM en bioinformática (HubBCB-14), bajo la dirección de @christinatoft.bsky.social en el @i2sysbio.bsky.social 5 meses, 20h/semana, 600euros/mes Solicitudes hasta 16 Abril '25 más información en: sede.csic.gob.es/tramites/pro... DM si interesado/a
Convocatoria JAE Intro @csic.es abierta! El @i2sysbio.bsky.social oferta 5 plazas para personas que tengan un grado en Ciencias durante 5 meses a media jornada. Ideales para estudiantes de máster en busca de un proyecto de iniciación a la investigación. Más info: sede.csic.gob.es/tramites/pro...
Convocatoria JAE Intro @csic.es abierta! El @i2sysbio.bsky.social oferta 5 plazas para personas que tengan un grado en Ciencias durante 5 meses a media jornada. Ideales para estudiantes de máster en busca de un proyecto de iniciación a la investigación. Más info: sede.csic.gob.es/tramites/pro...
Convocatoria JAE Intro ICU 2025 | Sede CSIC
Becas de introducción a la investigación para estudiantes universitarios.
sede.csic.gob.es
Tercer día de la #2AsambleaBCBHub. Tenemos el honor de contar con Elena Cartea de @csic-vaact.bsky.social abriendo la jornada contandonos las iniciativas de @csic.es en Conexiones y PTIs.
🚨El I2SysBio participa en los eventos internacionales celebrando la 'Biophysics Week' con el ya tradicional BIOPHYZZA 🍕🍻 *El evento es gratuito pero hay que inscribirse!* research.uv.es/biophyzza/ @i2sysbio.bsky.social @ucciuv.bsky.social @biophysicalsoc.bsky.social Ayudanos a difundir ↩️🙏
🌐Europe takes a major step towards digital autonomy in supercomputing and #AI with the launch of the DARE project 💻Based on #RISCV , this EuroHPC project coordinated by BSC will deliver high-performance & energy-efficient supercomputing for research & industry. 🔗 www.bsc.es/ZyZ
Really excited that Anna Niarakis will give the next CRCT #bioinformatics seminar on Friday 14th March at 11 in salle Cazaux!
Next, Ana Martinez and Carmen Gil from @cib-csic.bsky.social presenting how to use a consortium of AI tools for drug design, with múltiple applicatons in the clínic @bcbhubcsic.bsky.social @csic-vaact.bsky.social #2AsambleaBCBHub
Kickking off the second day our @bcbhubcsic.bsky.social meeting with scientific sesions with Victor Sánchez Gaya, presenting POSTRE, a tool to predict the funcional impact of pstructural variants @hitseq.bsky.social @ibv-csic.bsky.social @csic-vaact.bsky.social
@anaconesa.bsky.social opening the Second General Assembly of the @bcbhubcsic.bsky.social at the main @csic.es site. Three days of #compbio and #bioinfo discussions ahead!
🚨Job offer at our research institute I2SysBio 🇪🇸: Contract for International Program Management, specialized in ERC @erc.europa.eu programs 🧪 #science #researchgrants #JOBOFFER #i2sysbio @ucciuv.bsky.social @csic.es @uv.es i2sysbio.es/position/4/
i2sysbio - Position
i2sysbio.es
Unbelievable news. Pancreatic is one of the deadliest cancers. New paper shows personalized mRNA vaccines can induce durable T cells that attack pancreatic cancer, with 75% of patients cancer free at three years—far, far better than standard of care. www.nature.com/articles/s41...