🚨 Want to do your PhD or postdoc with us? Taking candidates for @GVA APOSTD (postdoc) & CIACIF (predoc) applications 🧬 long reads · single-cell & spatial · multi-omics · AI for biology 🧑‍⚕️🐭🐙🌍 human disease · model & non-model species · One Health 📩 conesalab@gmail.com, don't wait until the deadline!

🎉 Our TUSCO paper is out in Nature Communications! A new benchmarking framework for long-read transcriptome reconstruction using curated single-isoform genes as internal ground truth — no spike-ins needed, by talented @tianyuanliu.bsky.social 🧬🔗 nature.com/articles/s41467-026-72089-1

TUSCO: benchmarking transcriptome reconstruction with endogenous single-isoform controls - Nature Communications

Long-read sequencing enables comprehensive transcriptome characterization but remains challenging to benchmark due to sequencing errors, sample variability, and the limited scope of existing evaluatio...

nature.com

Excited to share the latest preprint from @conesalab.bsky.social. A new tool to visualize and filter isoforms based on SQANTI things within the UCSC Genome Browser. Awesome work led by @carolinamonzo.bsky.social and with collaboration from @ucscgenomics.bsky.social tinyurl.com/SQANTI-br #longreads

Ya está disponible la información del proyecto Squanti-epi en Converge del @csic.es. Este proyecto, liderado por @anaconesa.bsky.social y en colaboración con Longseq, es uno de los proyectos COCREA 2025. Más información: www.i2sysbio.es/communicatio... converge.csic.es/project/sqan...

Forgot spike-ins in your lrRNA-seq experiment? 😅 No problem! Our TUSCO benchmarks your transcript models using endogenous single-isoform genes as internal ground truth. Integrated in SQANTI3 for human & mouse. 🧬 Just out in @natcomms.nature.com @pacbio.bsky.social @nanoporetech.com rdcu.be/fkZCb

Delighted to share that the new @csic.es Ranking of Spanish Women Researchers places me in the top 2% Grateful for this recognition, and deeply aware that it reflects years of work, learning, and collaboration with my team and international colleagues @bcbhubcsic.bsky.social tinyurl.com/RankingCSIC

El grupo de investigación de @anaconesa.bsky.social en el #I2SysBio participa en un proyecto europeo para mejorar el trigo frente a la sequía y la falta de nutrientes. www.i2sysbio.es/communicatio...

I2SysBio (CSIC-UV) is taking part in a European project to improve wheat’s resilience to drought and nutrient deficiency

<p><strong>&bull; The Institute of Integrative Systems Biology is participating in one of the projects funded by the European Innovation Council to develop innovative, high-risk technologies</strong><...

i2sysbio.es

@anaconesa.bsky.social @i2sysbio.es participa en la mesa “Digitalización y uso de la IA” del Congreso de Sostenibilidad y Economía Circular Aplicada-CSECA @pti-sosecocir.bsky.social, destacando cómo reducir la huella de carbono en computación para impulsar la sostenibilidad y la economía circular.

🏆 La @sebibc.bsky.social lanza la I Edición del Premio Nacional de Bioinformática y Biología Computacional . 🗓️ Candidaturas hasta el 30 junio 2026 💶 Premio: 5.000 € + keynote en SEBiBC 2026 (Toledo) 🔗 Bases: www.sebibc.es/premio-nacio... @bcbhubcsic.bsky.social

Excited to start the Third General Assembly of the @bcbhubcsic.bsky.social with top tier talks, collaborative lectures and important @csic.es computational insights. And of course discussing how to move ahead another year!!

Muy orgullosa de anunciar la Escuela de Verano en Bioinformática Avanzada @bcbhubcsic.bsky.social, junto a @sebibc.bsky.social. Presenta avances recientes en formato “train the trainer”, con materiales reutilizables, ideal para profesionales y docentes que enseñan bioinformática. tinyurl.com/EscVern

The “curse of interdisciplinarity”: Fields like bioinformatics fall between the cracks in grant evaluation. 🧬 For bios: Too little mechanistic validation 🧮 For math: Not enough new theory 💻 For computing: “Just” applied computing Interdisciplinarity is essential, but evaluation hasn’t caught up.

How do host-microbe interactions are affected in spaceflight? This question can be addressed with squids, RNA-seq and bioinformatics! Read the whole paper here. Memorable collaboration with @jamiefoster.bsky.social from @ifas.ufl.edu @bcbhubcsic.bsky.social @i2sysbio.es

Frontiers | Beneficial microbes mitigate molecular stress responses and accelerate developmental pathways in host animals during spaceflight

As humans continue the manned exploration of space, it is critical to understand the impact of this harsh environment on the beneficial microbes that interac...

links.email.frontiersin.org

🤔 ¿Estas buscando tu primer contacto real con el mundo de la investigación? Entonces, ¡deja de buscar más y aprovecha esta oportunidad! En el ConesaLab ofrecemos dos posiciones dentro de las becas hashtag#JAEIntro del CSIC. 20 horas/semana / 7 meses / 600 € mensuales tinyurl.com/JAE-ConesaLab

Tomorrow I will be delivering a keynote talk at the Swiss Bioinformatics Workshop @ Göteborg, discussing how multiomics research advances thanks to tool development. Love the fun facts, b.t.w @bcbhubcsic.bsky.social @hitseq.bsky.social @iscb.bsky.social

Presentación del informe Science4Policy elaborado por la @bcbhubcsic.bsky.social y PTI neuroenvejecimiento. “La IA va a ser fundamental para abordar los retos de una sociedad que envejece” Javier de las Rivas explica este trabajo en nombre del equipo de redacción.

Euphoric for my institute @i2sysbio.es receiving the 2nd @csic.es Sustainability Prize. Proud of the tireless & impactful work of our Committee. Especially happy to share recognition with friends from IDAEA & @geo3bcn-csic.bsky.social. Congrats @icmabcsic.bsky.social and @ibmb-csic.bsky.social

Yesterday I had the privilege of joining the “fishbowl” at the AX Aula Forum in Murcia. Inspiring conversations on technology, humanism, aging, and global health.

Honored to assume the Presidency of the Spanish Society of Bioinformatics and Computational Biology (SEBiBC). Looking forward to working with our members and the broader bioinformatics ecosystem in Spain to strengthen collaboration and visibility @bcbhubcsic.bsky.social www.sebibc.es/quienes-somos/

🚀 Registration is now OPEN! longtrec.eu/VALT/ Join us in Valencia, Spain for the first symposium dedicated to #LongReadsTranscriptomics 🧬, with a dream set of keynote speakers. @pacbio.bsky.social @nanoporetech.com @elixir-europe.org @iscb.bsky.social @hitseq.bsky.social @i2sysbio.es

We can't wait to see you in Valencia this summer at VALT! Abstract submission deadline 📅 March 31st. #LongReadsTranscriptomics

Ana Conesa@anaconesa.bsky.social · 7mo ago

🚀 Registration is now OPEN! longtrec.eu/VALT/ Join us in Valencia, Spain for the first symposium dedicated to #LongReadsTranscriptomics 🧬, with a dream set of keynote speakers. @pacbio.bsky.social @nanoporetech.com @elixir-europe.org @iscb.bsky.social @hitseq.bsky.social @i2sysbio.es

🧬🌍 #ISMB2026 is accepting abstracts! Share new, in-progress, or recently published work in #bioinformatics and #computationalbiology with a global audience.  Deadline: Thursday, April 9, 2026 📥Submit here: https://www.iscb.org/ismb2026/call-for-submissions/abstracts @anaconesa.bsky.social

Congratulations, @anaconesa.bsky.social ! #rnaseq #longreads #bioinformatics

I2SysBio@i2sysbio.es · 6mo ago

Two #I2SysBio projects, led by Ana Conesa, selected for the CSIC COCREA 2025 programme The funded initiatives aim to improve our understanding of the microbiome’s role in reproductive health and advance research in epitranscriptomics. www.i2sysbio.es/communicatio...

🚀 Registration is now OPEN! longtrec.eu/VALT/ Join us in Valencia, Spain for the first symposium dedicated to #LongReadsTranscriptomics 🧬, with a dream set of keynote speakers. @pacbio.bsky.social @nanoporetech.com @elixir-europe.org @iscb.bsky.social @hitseq.bsky.social @i2sysbio.es

📣 Abstract submissions for #ISMB2026 are open! Submit your #computationalbiology research for a chance to present at the premier conference in the field. 📅 Submission deadline: Thurs, April 9, 2026 📥Submit here: https://www.iscb.org/ismb2026/call-for-submissions/abstracts @anaconesa.bsky.social

Transcriptomics in the era of long-read sequencing #Review by @carolinamonzo.bsky.social, Tianyuan Liu & @anaconesa.bsky.social @conesalab.bsky.social @csic.es Free to read here: rdcu.be/efBjP

Transcriptomics in the era of long-read sequencing

Nature Reviews Genetics - Advances in long-read sequencing are driving the implementation of these technologies for transcriptome profiling. The authors provide a comprehensive guide to long-read...

rdcu.be

Our latest preprint on how to best combine multiple samples in lrRNA-seq experiment. Not, trivial as your capacity for detecting known and novel transcripts is affected. We discovered that results depend on data and reconstruction algorithm. @nanoporetech.com @pacbio.bsky.social tinyurl.com/4pnnbd92

To join or not to join: handling biological replicates in long-read RNA sequencing data

Long-read RNA sequencing (lrRNA-seq) has revolutionized transcriptomics facilitating the study of alternative splicing and resulting in identification of thousands of novel transcripts. While isoform ...

biorxiv.org

I am SOOO excited to welcome our brand-new VEGA instrument, made possible through a collaboration among @uv.es @i2sysbio.es and @pacbio.bsky.social . Months ago, we fantasized about having one, and now this is a reality. I can´t wait to run the many projects we have in the pipeline!

. @patrickoshag.bsky.social discusses data centers on space with @gavinsbaker