📢New Community Page describing #grafifyonline a browser-app that provides publication-quality graphs and statistical analysis. I hope you the community finds it useful! journals.plos.org/plosbiology/...

grafify online: A web app for graphing and statistical analysis

Creating accurate graphs and performing statistical analyses can be challenging for those who lack coding experience. This Community Page introduces grafify online, a free, browser-based app for gener...

journals.plos.org

📢 Been off social media, but never too late to say our story on #GBP1 was published in EMBO J. Check it out here. link.springer.com/article/10.1...

GBP1 recruitment to actin-rich pedestals of extracellular Gram-negative bacteria promotes pyroptosis - The EMBO Journal

The IFNγ-induced GTPase guanylate-binding protein 1 (GBP1) binds to lipopolysaccharide (LPS) on cytosolic gram-negative bacteria and promotes pyroptosis via the recruitment and activation of caspase-4...

link.springer.com

Avinash Shenoy@avishenoy.bsky.social · 10mo ago

📢A new effector-triggered immunity role for GBP1! No place for pathogens to hide now that GBP1 can detect extracellular pathogens that hijack the actin cytoskeleton. Surprise*suprise* GBP1 does this independently of LPS! 🧵 biorxiv.org/content/10.1...

#InflammaZoom free Webinar is back on Monday October 20th! With James Murphy (WEHI, Melbourne, Australia) @pseudokinase.bsky.social and Jonathan Maelfait (VIB-UGent, Ghent, Belgium) Register now: bit.ly/4iXGqjw

📢A new effector-triggered immunity role for GBP1! No place for pathogens to hide now that GBP1 can detect extracellular pathogens that hijack the actin cytoskeleton. Surprise*suprise* GBP1 does this independently of LPS! 🧵 biorxiv.org/content/10.1...

📢 paper - a new class of RIPK1 inhibitors. Lots of with here, with structure of it bound to RIPK1, biochemistry and more! Was fun being part of this with Tate group and many others. pubs.acs.org/doi/10.1021/...

A bit late, but never too late to spread the word on influenza M2 protein cleavage by caspase-6. Great PhD work by Carmen along with @bealelab.bsky.social @imperialinfect.bsky.social

EMBO Reports@emboreports.org · last yr.

Rupert Beale @bealelab.bsky.social and co-workers @crick.ac.uk @imperialcollegeldn.bsky.social show that #caspase cleavage of #influenza A #virus M2 disrupts M2-LC3 interaction and regulates virion production. -> www.embopress.org/doi/full/10....

Interesting talks today on sustainability in education in the Festival of Learning and Teaching @imperialinfect.bsky.social

I am super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳 Using cryo-electron tomography 🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!  www.biorxiv.org/content/10.1...

📢 I'll be hosting Jack Aunty & Kesavardana Sannula in the next InflammaZoom seminar series on Monday 20th Jan at 8am GMT, 1:30pm IST, 7pm AEDT. Register here: @keshu-vrimmch.bsky.social events.abcam.com/event/Inflam...

The CSC is currently accepting applications to this scheme. Details here: cscuk.fcdo.gov.uk/scholarships...

Avinash Shenoy@avishenoy.bsky.social · 2y ago

Last week we welcomed Dharitri Chaudhuri, a PhD student from Sandhya's lab at IISc Bangalore. During her placement, she will work on a major problem in countries like India: EPEC infections & diarrhoeal disease. Thanks to funding from the Commonwealth Scholarships cscuk.fcdo.gov.uk/scholarships...

This month we welcomed our newest PhD student, Ayush Punwatkar, who is funded by the National Overseas Scholarship from the Govt of India. He's going to work on, what else, inflammasomes 😉

Calling all science enthusiasts and medical professionals! We have an incredible lineup of events this week that you won't want to miss. Whether you're passionate about medical research, mental health, or cardiac care, there's something for everyone. Don’t miss out! 🧵[1/6] #ScienceSky #MedicineSky

Last week we welcomed Dharitri Chaudhuri, a PhD student from Sandhya's lab at IISc Bangalore. During her placement, she will work on a major problem in countries like India: EPEC infections & diarrhoeal disease. Thanks to funding from the Commonwealth Scholarships cscuk.fcdo.gov.uk/scholarships...

Hello science folks... 👋 Hoping the ride here is smoother!