@bbkrage.bsky.social

Wonderful - thanks @gomobel.bsky.social for the write-up and for getting the feedback from important characters in the IDP field as @ProfJaneClarke and in mirror-image biology Michael S. Kay.

Fer @gomobel.bsky.social · 2y ago

Debunked dogma: disordered proteins disregard ligands’ chirality 🧬 my latest story for @chemistryworld.bsky.social on a fantastic and surprising Nature paper by Johan Olsen and Birthe Kragelund teams 🇩🇰 Read more below! #realtimechem #chemsky 🧪 www.chemistryworld.com/news/debunke...

Have you looked in the mirror recently? We took a good look at stereochemistry and how D- and L-ligands bind ... its all about disorder! Exited to share a true REPIN collaborative work led by @estellaan.bsky.social, A. Due and J. Olsen. Thanks for support NNF and DFF. rdcu.be/d1F6q

Stereochemistry in the disorder–order continuum of protein interactions

Nature - Studies on protein–protein interactions using proteins containing d- or l-amino acids show that stereoselectivity of binding varies with the degree of disorder within the complex.

rdcu.be