DCI–Bern Practical Workshop on CEMOVIS 2026 — registration open. Hands-on workshop on Cryo-Electron Microscopy of Vitreous Sections (HPF → cryo-sectioning → cryo-TEM), Institute of Anatomy, University of Bern, with MIC & DCI-Bern. 🧵👇

New paper in Nature Communications: we identified ANTXR2 (CMG2) as the cellular receptor for C. perfringens NetF toxin, causing hemorrhagic enteritis in dogs and foals. ANTXR2 was previously known as the receptor for anthrax toxin PA. doi.org/10.1038/s414...

Identification and structural characterization of anthrax toxin receptor 2 as the Clostridium perfringens NetF receptor - Nature Communications

This study identifies ANTXR2 as the cellular receptor for Clostridium perfringens toxin NetF and determines its structure bound to the toxin using cryo-EM, revealing a distinct lateral binding mechani...

doi.org

Paper alert🚨 Label your protein of interest and localize it in cryoET 👁️❄️ Genetically encoded FerriTag as a specific label for cryo-electron tomography: Structure www.cell.com/structure/fu...

Genetically encoded FerriTag as a specific label for cryo-electron tomography

Wang et al. present an optimized labeling strategy for cryo-electron tomography based on genetically encoded FerriTag. This system uses rapamycin to recruit iron-loaded ferritin to target proteins, en...

cell.com

We are hiring-join us!

FMI science@fmiscience.bsky.social · 11mo ago

🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬 Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...

In collaboration with the Posthaus Lab, we identify ANTXR2—also the anthrax toxin receptor—as the receptor for Clostridium perfringens NetF pore forming toxin. Cryo-EM shows extensive contact between the pore and the receptor 🧬🧊🔬 #Microbiology #CryoEM #PoreFormingToxins doi.org/10.1101/2025...

A plain language overview of our recent publication link.growkudos.com/1bt0psurksg

Near-atomic detail from large sample areas using cryo-EM of frozen biological sample slices

This study explores how cryo-electron microscopy (cryo-EM) can be used to image large areas of frozen biological samples with near-atomic resolution. The researchers used a method called CEMOVIS, whic...

link.growkudos.com

Out now at IUCJ doi.org/10.1107/S205...

In situ high-resolution cryo-EM reconstructions from CEMOVIS

Vitreous sectioning (CEMOVIS) is an alternative to FIB milling for generating thin samples suitable for cryo-EM imaging. We show that CEMOVIS samples preserve the high-resolution structural details of...

doi.org

Benoît Zuber@benoitzuber.bsky.social · last yr.

Happy to announce our latest preprint. High resolution ribosomes in cells obtained on CEMOVIS (frozen-hydrated sections) www.biorxiv.org/content/10.1... in collaboration with @grigoriefflab.bsky.social and Wanda Kukulski.

Happy to announce our latest preprint. High resolution ribosomes in cells obtained on CEMOVIS (frozen-hydrated sections) www.biorxiv.org/content/10.1... in collaboration with @grigoriefflab.bsky.social and Wanda Kukulski.

www.biorxiv.org/content/10.1... NEW PREPRINT ALERT! Thanks to all involved!

Please check out our latest cryo-EM structure in the Journal of Structural Biology X: Structure of the PTS glucose transporter IICB stalled in an intermediate conformation. www.sciencedirect.com/science/arti... Congratulations Patrick for this great work !

Cryo-EM structure of a phosphotransferase system glucose transporter stalled in an intermediate conformation

The phosphotransferase system glucose-specific transporter IICBGlc serves as a central nutrient uptake system in bacteria. It transports glucose acros…

sciencedirect.com

Great position for a postdoc to join @igreger.bsky.social’s group in the LMB’s Neurobiology Division, using diverse methods to study synaptic AMPA glutamate receptors. Read more about the job here: www.nature.com/naturecareer... Apply by 20 FEB #PostdocJobs #ScienceJobs

Come and set up your own group at the @mrclmb.bsky.social in Cambridge, UK. Feel free to chat/email me with questions.

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 2y ago

Join our Structural Studies Division, leading a research group developing computational methods to address questions in molecular & cellular biology! You will be supported by core funding, excellent facilities & enthusiastic colleagues. Apply by 18 MAR www.nature.com/naturecareer...

Our latest JACS paper: high-resolution cryoEM of #aerolysin in lipid environment shows pore properties and 4 key constriction rings for #nanopore sensing. Collaboration with #DalPeraro & #Cao labs. @coldpopeye.bsky.social @unibern.bsky.social #EPFL #UNIGE #DubochetCenter #MIC shorturl.at/qyzbb

Aerolysin Nanopore Structures Revealed at High Resolution in a Lipid Environment

Aerolysin is a β-pore-forming toxin produced by most Aeromonas bacteria, which has attracted large attention in the field of nanopore sensing due to its narrow and charged pore lumen. Structurally sim...

shorturl.at

🎉Our latest publication "Predicting Polypharmacology with Web-Based Tools" by @maedehdarsaraee.bsky.social, Sacha Javor, and Jean-Louis Reymond is now published on Wiley! Read it here👉 onlinelibrary.wiley.com/doi/abs/10.1... #DCBP #polypharmacology #target_prediction #chembl #fingerprint #ML

Reminder: Outstanding opportunity to open your group in the LMB’s Neurobiology Division as part of our Molecular Connectomics Initiative! You will be supported by core funding, excellent facilities and a lively international community of researchers. Apply by 19 Jan www.nature.com/naturecareer...

Our January cover shows a reconstructed synapse from a cryo-electron tomogram of cultured hippocampal neurons expressing a SNAP-25 mutant, using CryoVesNet developed by Amin Khosrozadeh, Benoît Zuber et al. (https://buff.ly/4h0DjGN). JCB's January issue is here ✨ https://buff.ly/3ZZLqwE