Help us untangle repetitive genomic variants! 🧬 We’re looking for an undergrad/master's intern (4 months, Spring 2027) with Python & Bash skills to map regulatory sequences in structural variants in the Bernardo Rodriguez Martin lab. Details & apply: tinyurl.com/mtkknphc #TEsky

Contribution from the REPBIO team at @crg.eu (Layla Diaz, @jemilianosf.bsky.social, and myself) to the Volume 116 of Advances in Genetics, on Transposable Elements in Health and Disease, edited by @epiageing-lab.bsky.social sciencedirect.com/science/chap... [1/5]

Are you a professor / group leader looking for a course to teach that would be extremely welcomed by graduate students & postdocs? Come train with us in how to teach the tools of the creative scientific process in our European train the trainer event in Heidelberg. night-science.org/train-the-tr...

📢📢 Job opening between the Bioinformatics Unit and my group (REPBIO) at @crg.eu Interested in contributing to our efforts to leverage long-read sequencing technologies for human genome research? Join us in Barcelona: recruitment.crg.eu/content/jobs... Please repost😊

Transcription start sites are new mutational hotspots, according to a new study by the CRG's Donate Weghorn in Nature Communications. The mutations can be passed down to future generations and appear shortly after conception, in the first few rounds of cell division.

Transcription start sites experience a high influx of heritable variants fueled by early development - Nature Communications

The impact of transcription on germline mutagenesis remains poorly understood. Here, the authors identify a mutational hotspot at transcription start sites in the human germline that is significantly ...

nature.com

Our annual PhD call is closing at the end of this week on 30 November. If you're interested in carrying out world-class scientific research in Barcelona, you still have a few days left to submit your application! www.crg.eu/en/content/t...

Thinking about doing a PhD with us? We're running an online Q&A session just for you! Hear practical advice directly from our experts in the Training and Academic Office and register here: events.teams.microsoft.com/event/26a7dc...

All set for "Meet the Companies"❗️ A unique gathering connects PRBB residents with a dozen leading companies in diagnostics, gene editing, venture capital, patent law, scientific management, communication and citizen science. 🗓️4 November, 15h ℹ️

"Meet the companies": a chance to boost your career - El·lipse

In this yearly event, PRBB residents get to know professional opportunities beyond academia through informal conversations with companies on a wide range of areas in the biomedical and biotech sector.

tuit.cat

Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you. More info: www.crg.eu/en/content/t...

The secret to the naked mole-rats’ extraordinarily long life may lie in subtle changes to just four amino acids, researchers report in Science. https://scim.ag/3IUquTb

A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging

Efficient DNA repair might make possible the longevity of naked mole-rats. However, whether they have distinctive mechanisms to optimize functions of DNA repair suppressors is unclear. We find that na...

scim.ag

Next was Bernardo Rodriguez-Martín ( @bernardo-rodriguez.bsky.social ), from the EvoMG Program and @crg.eu, on highly mutagenic (hot) L1 polymorphisms in cancer

🚀🧬🔥 Hot off the press — 2025! Don’t miss this must-read publication: bit.ly/4mJwFb7 This groundbreaking paper sets the stage for Earth BioGenome Project Phase II — where EBP is gearing up to scale genome sequencing 10× faster than ever before! 🌍✨

We are excited that the Earth BioGenome Project, a global network of scientists including those from the Sanger Institute, has mapped the second phase of its ambitious plan to sequence all 1.67 million known species on Earth by 2035. 👏 www.sanger.ac.uk/news_item/bi...

Biological ‘moonshot’ accelerates efforts to genetically map life on earth

A global collaboration that includes experts at the Wellcome Sanger Institute has mapped out the second phase of its ambitious plan to sequence all 1.67 million known species on Earth by 2035.

sanger.ac.uk

Earth BioGenome Project 🌍@ebpgenome.bsky.social · 12mo ago

🚀🧬🔥 Hot off the press — 2025! Don’t miss this must-read publication: bit.ly/4mJwFb7 This groundbreaking paper sets the stage for Earth BioGenome Project Phase II — where EBP is gearing up to scale genome sequencing 10× faster than ever before! 🌍✨

A great thing about working in a lab is being involved in lab meetings and witnessing everyone's projects take shape. A single project may seem to go slow but all projects together is impressive. Caroline Bartman discussed this on the podcast: podcasts.apple.com/us/podcast/2... @cbartman.bsky.social

28 | Caroline Bartman and the flash(cards) of inspiration

Podcast Episode · Night Science · 02/13/2023 · 28m

podcasts.apple.com

Sequence-resolved mobile element sagas, Chapter 3: “MEI at population scale” This work closes our trilogy on MEI research advances enabled by long-read sequencing. Bonus tutorial about MEI of our structural variation study of 1KGP samples resequenced using @nanoporetech.com [1/9]

Samarendra Pani@samarendra-pani.bsky.social · last yr.

[1/8] *New Open-Access Long Read Resource*. We sequenced 1,019 genomes from the 1000 Genomes Project sample cohort using @nanoporetech.com long-read sequencing (LRS) to median 17x coverage. Publication at go.nature.com/4ffPb8f. @hhu.de @crg.eu @embl.org @impvienna.bsky.social

Congratulations to all awardees with a #PID2024!! 🥳 extremely happy and thrilled to share our project proposal (L1-CANPREDICT) got funded. Keep tuned about the research to come from REPBIO at @crg.eu

Travel broadens the mind – an excellent example of that is EMBL ARISE Fellow Thomas Weber, who expanded his data science skills during his secondment at @scilifelab.se. 👇 Read the full story about his journey and the impact of his ARISE Fellowship. www.embl.org/news/people-...

[1/8] *New Open-Access Long Read Resource*. We sequenced 1,019 genomes from the 1000 Genomes Project sample cohort using @nanoporetech.com long-read sequencing (LRS) to median 17x coverage. Publication at go.nature.com/4ffPb8f. @hhu.de @crg.eu @embl.org @impvienna.bsky.social

EMBL researchers and their collaborators have provided exciting new insights into human genetic variation by building upon the 1000 Genomes Project dataset. The two studies constitute what may be the most complete overview of the human genome to date. www.embl.org/news/science...

The first, co-authored by @bernardo-rodriguez.bsky.social, discovered more than 167,000 structural variants across the 1,019 individuals, doubling the known amount of structural variation in the human pangenome. Most variants were rare, which will help accelerate the diagnosis of rare diseases.