SciLifeLab
@scilifelab.se
🇸🇪 Sweden's national center for molecular biosciences 👩🔬 Infrastructure with unique technologies and expertise 👥 Research community 🥼 Life science 🌱 💻 Often data-driven https://www.scilifelab.se/ https://www.linkedin.com/company/scilifelab/
SciLifeLab drug discovery expert Per Arvidsson explains the @nobelprize.org in chemistry 2026 for asymmetric synthesis chemistry. 🧪 The prize rewards fundamental research that demonstrates how life on earth theoretically could become “homochiral”. Read more ↓ www.scilifelab.se/news/on-the-...
“Optogenetics has revolutionized how we study the brain”. Hear insights into this year’s @nobelprize.org in Physiology or Medicine from SciLifeLab Fellow @iskrapollak.bsky.social and SciLifeLab electrophysiology expert Nina Ottosson ↓ 🧪 www.scilifelab.se/news/insight...
Insights into the Nobel Prize in Physiology or Medicine
"As an electrophysiologist, I'm especially excited to see a Nobel Prize that puts ion channels in the spotlight. It is a remarkable example of how fundamental research can lead to breakthroughs that c...
scilifelab.se
Great collaborative paper just came off the press: Systematic identification of p11 as a signaling modulator across the GPCRome | #ScienceAdvances www.science.org/doi/10.1126/... @kthuniversity.bsky.social @scilifelab.se @ki.se @rockefeller.edu
Systematic identification of p11 as a signaling modulator across the GPCRome
The microprotein p11 (S100A10) is a ubiquitously expressed molecular scaffold that is known to be required for behavioral responses to certain antidepressants, presumably through its effect on G prote...
science.org
CUT&ID does Genomics+Proteomics in one shot via the fusion protein Lazarus Out @narjournal.bsky.social Unstoppable @annanordin.bsky.social is thinker+executor Get in touch if you wish to try it—plasmid soon @addgene.bsky.social 🙏 @liu.se @scilifelab.se @kawresearch.bsky.social @cancerfonden
Claudio Cantù@claudiocantu81.bsky.social · 10mo agoCan one map the genome-wide binding (1) and its protein partners (2) simultaneously from the same sample? Yes, one can. with CUT&ID ✂️🪪 Spearheaded — singlehandedly — by @annanordin.bsky.social No need of transgenesis, cloning and overexpression. Check it out, it's fast and its works.
The protein p11 interacts with numerous receptors targeted by commonly used medicines, opening new possibilities for treating conditions like pain, inflammation and depression. Study from KI, @scilifelab.se & @rockefeller.edu published in Science Advances 🧪 #Pharmacology news.ki.se/protein-foun...
Protein found to regulate dozens of important drug targets
A small protein known as p11 may play a much broader role in cellular signaling than previously thought. Researchers at Karolinska institutet have now shown that p11 interacts with numerous receptors ...
news.ki.se
For his “ground-breaking contributions to #MolecularBiotechnology and #genomics, in particular the development of #SpatialTranscriptomics”, Joakim Lundeberg (SciLifeLab/KTH) is awarded the @scienceacademyswe.bsky.social Gold Medal 2026! 🧪 More ↓ www.iva.se/en/published...
Today, we were honored to welcome Nobel laureate Stefan Hell 🧪 “I hear Stefan speak about his research once a year, and I’m always amazed how much has happened,” says SciLifeLab Director Jan Ellenberg. Hell received the 2014 Nobel Prize in Chemistry.
A new paper from my lab is out in @nature.com #npjDigitalMedicine! We combine #multiomics, #machinelearning & identified aggressive tumors within #lowrisk #NCCN #prostatecancer. Thanks @vetenskapsradet.bsky.social , @scilifelab.se @kawresearch.bsky.social for supporting us! tinyurl.com/35dzy54c
tinyurl.com
Fantastic energy at Nordic Life Science Days! 🧪 Here, Per Lek (SciLifeLab), Magnus Lejelöv (STUNS) & Knut Steffensen (@ki.se ATMP Center) break down key themes of Nordic #LifeScience: 💡 #HealthData as a competitive advantage 🧭 The Nordic #ATMP engine & local ecosystems youtube.com/shorts/6bJ2M...
What a fantastic energy at Nordic Life Science Days! ✨
YouTube video by SciLifeLab
youtube.com
A new study led by Erdinc Sezgin (@sciezgin.bsky.social) has developed a method for measuring the physical properties of cell membranes in thousands of individual immune cells simultaneously! 🧪 Read more in the article below ↓ www.scilifelab.se/news/a-new-w...
A new way to read immune cells through their membranes
A new study published in Nature Chemical Biology by researchers from SciLifeLab and Karolinska Institutet has developed a method for measuring the physical properties of cell membranes in thousands of...
scilifelab.se
This line “happy to skip writing for the next deadline”!!!! 🥹🥹🥹 Congrats to Florian and the team!
SciLifeLab@scilifelab.se · last mo.“I'm grateful, freaking out, humbled, very excited about what we’re going to do, happy to skip writing for the next deadline, and eager to celebrate with my wonderful team!” says Florian Rosenberger (SciLifeLab/@ki.se) after receiving an @erc.europa.eu Starting Grant 🧪 #proteomics #MassSpec
“I'm grateful, freaking out, humbled, very excited about what we’re going to do, happy to skip writing for the next deadline, and eager to celebrate with my wonderful team!” says Florian Rosenberger (SciLifeLab/@ki.se) after receiving an @erc.europa.eu Starting Grant 🧪 #proteomics #MassSpec
A “smörgåsbord of feelings”: Florian Rosenberger celebrates €1.5M ERC Starting Grant
Florian Rosenberger receives a ERC Starting Grant, and adds his name to the growing list of SciLifeLab Fellows receiving prestigious grants.
scilifelab.se
Advanced #3Dimaging and #SpatialTranscriptomics are brought together to better understand #PulmonaryHypertension – a life-threatening condition for which current treatments can slow disease progression and relieve symptoms, but not target the underlying cause. ↓ 🧪 www.scilifelab.se/news/combini...
Combining 3D imaging and spatial biology to understand pulmonary hypertension
Pulmonary hypertension is a life-threatening condition for which current treatments can slow disease progression and relieve symptoms, but not target the underlying cause. A demonstrator project…
scilifelab.se
Feeling the Monday grumpies? 🦭 The #ERGA Genome Report for the Mediterranean monk seal might just cheer you up! 🧬➡️ open-research-europe.ec.europa.eu/articles/6-195 @biogeneurope.bsky.social @ebpgenome.bsky.social #conservation #genomes for #biodiversity #seal 📷 by James Eaton
📣 Submit your abstract for Integrating Scales in #PlanetaryBiology2026 until September 7! 🧪 Submit talks & posters in - Integrative Approaches in #PlanetaryBiology - #ClimateResilience - Sustainable Food Systems - #Biodiversity Decline 👉 Program & registration: lyyti.events/p/Integratin... @uu.se
Integrating Scales in Planetary Biology
lyyti.events
Our annual flagship event, the SciLifeLab Science Summit, this year unites world-leading #cancer researchers with cutting-edge technologies across #genomics, #proteomics, #imaging, #DataScience and beyond 🧪 🗓️ October 14, 2026 More info and registration ↓ www.scilifelab.se/event/scilif...
SciLifeLab Science Summit
The Annual Conference SciLifeLab Science Summit is a one-day symposium with a new topic each year. The 2026 topic is: Cancer Research: Translating Life Science Discoveries to Clinical Breakthroughs Fo...
scilifelab.se
Our colleagues @scilifelab.se organise 2 conferences in Oct/Nov, "Integrating Scales in Planetary hashtag#Biology" and the "Long-Read Users Annual 2026". Both in Uppsala (Sweden). Both consecutive. More info: biodiversitygenomics.eu/conferences-... @ergabiodiv.bsky.social @iboleurope.bsky.social
Upcoming interesting conferences at SciLifeLab - BGE+
SciLifeLab organises two consecutive conferences by the end of October and the beginning of November 2026. A great opportunity to spend a few formative days in Uppsala! Integrating Scales in Planetary...
biodiversitygenomics.eu
New paper alert 🎇 in @biologists.bsky.social Journal of Cell Science.. Cell surface remodeling caused by the loss of the flippase subunit TMEM30A in immune cells: journals.biologists.com/jcs/article/...
Cell surface remodeling caused by the loss of the flippase subunit TMEM30A in immune cells
Summary: TMEM30A loss disrupts membrane lipid asymmetry, increasing phosphatidylserine exposure, membrane dynamics and surface remodeling, linking flippase dysfunction to immune cell interactions.
journals.biologists.com
To learn the latest techniques in #StructuralBiology, participants travel to Stockholm, Linköping, Lund, and Gothenburg across two weeks, in the Integrated Structural Biology course organized by SciLifeLab and NordStruct. 🧪 More ↓ www.scilifelab.se/news/demysti... #MolBiol #Imaging
"It’s harder than it looks": demystifying structural biology across sweden
“It feels like a pretty natural progression in my career, to start picking up these methods that complement what I do, to become an even better structural biologist. There’s a lot of talk about integr...
scilifelab.se
New paper alert 💥 "Spectral biophysical cytometry with nanosensors reveals remodelling of immune cells in atherosclerosis" Open access paper here: www.nature.com/articles/s41...
Spectral biophysical cytometry with nanosensors reveals remodelling of immune cells in atherosclerosis - Nature Nanotechnology
Membrane-permeant, environment-sensitive nanosensors enable high-throughput, multiparametric quantification of membrane order and mitochondrial potential, revealing immune-cell-specific remodelling an...
nature.com
16 new Swedish funders are now represented in the #OpenAIREGraph. Connecting funding with #publications, #datasets, and #software helps create a more complete picture of research activity. 🔗 See how we worked with @scilifelab.se to make it happen shorturl.at/CswoS
🔝 What great news! 🥇Professor @tuuliel.bsky.social (@nygenome.org, @scilifelab.se) has received the prestigious European Society of Human Genetics Award Really proud of this well-deserved recognition of a member of our Scientific Advisory Board at CNAG #ESH2026 #ESHG @eshg.bsky.social
FASTEN YOUR SEATBELTS: Tamina Weiss, inspired by previous data from @ppagella86.bsky.social found that beta-catenin is more than an adaptor protein downstream of #WNT It is an orchestrator that scouts and opens enhancers for transcriptional activation @biorxivpreprint.bsky.social
bioRxivpreprint@biorxivpreprint.bsky.social · 4mo agoEnhancer pioneering activity of Wnt/β-catenin signaling https://www.biorxiv.org/content/10.64898/2026.06.12.731851v1
Hepatoblastoma is a nasty childhood liver cancer driven by mutant β-catenin How tumor cells get different and more or less aggressive? We found this out w Peng & Thomas from the Princess Maxima Center for Pediatric Oncology & @annanordin.bsky.social @liu.se @pnas.org www.pnas.org/doi/10.1073/...
Differential Wnt/β-catenin signaling via TCF7L2/LEF1 binding specificity shapes cellular and tumor phenotypes | PNAS
The mechanisms by which Wnt/β-catenin signaling regulates gene expression in a tissue- and context-specific manner remain poorly understood, limiti...
pnas.org
After #sailing to #Antarctica through the world’s harshest waters, Jean Hausser (SciLifeLab/@ki.se) releases a book about his journey and #leadership lessons 🧪 Hear about freezing temperatures, teamwork under pressure, and the mental clarity that comes from complete isolation: youtu.be/ZELWHhGq8jg
Sailing the world’s harshest waters to Antarctica – Jean Hausser's learned self-leadership
YouTube video by SciLifeLab
youtu.be
Ny forskning av @iskrapollak.bsky.social m fl visar att antidepressiva läkemedel påverkar olika serotoninceller i hjärnan på olika sätt. Detta kan förklara varför biverkningar ofta uppstår i början av en behandling, medan förbättringen kommer först senare. @scilifelab.se www.su.se/enheter/inst...
My collaborator @ospjuth.bsky.social is recruiting a postdoc in cell biology to work on CRISPR perturbation and high-content imaging as part of our TIMED NEST project. Amazing team, please share! For information on how to apply, see the ad below: www.uu.se/en/about-uu/... #chemsky #chemjobs
Postdoc in Cell Biology – CRISPR Perturbation and High-Content Imaging - Uppsala University
Postdoc in Cell Biology – CRISPR Perturbation and High-Content Imaging, Department of Pharmaceutical Biosciences, Uppsala University
uu.se
Despite the prize money, what most winners highlight each year is the week in Stockholm. Here, they get to see the city during Nobel week and mingle with the laureates, get to see some cool instruments at SciLifeLab and meet with high-level researchers in their fields. 🧪 youtu.be/HJzPbuP8xvE
The future of life science: insights from the Science & SciLifeLab Prize 2025 winners
YouTube video by SciLifeLab
youtu.be
