@bilderlab
@bilderlab.bsky.social
Epithelial biology: polarizing proteins, elongating eggs, and cold-blooded cancer
I've had a bit of a hiatus due to faculty job apps, but the Etsy shop is open again and ready for your holiday orders! All proceeds go to @flybase.bsky.social , and I just sent the August/September revenue donation. So grab some #drosophila stocking stuffers =>
FWIW we also find that flies show coagulopathy, another big cause of death of cancer patients pubmed.ncbi.nlm.nih.gov/37354901/
Systemic coagulopathy promotes host lethality in a new Drosophila tumor model - PubMed
Malignant tumors trigger a complex network of inflammatory and wound repair responses, prompting Dvorak's characterization of tumors as "wounds that never heal."<sup>1</sup> Some of these responses le...
pubmed.ncbi.nlm.nih.gov
Maybe referring to a 2015 paper from our lab? pubmed.ncbi.nlm.nih.gov/25850672/ @perrimonlab.bsky.social published back-to-back: pubmed.ncbi.nlm.nih.gov/25850671/.
Malignant Drosophila tumors interrupt insulin signaling to induce cachexia-like wasting - PubMed
Tumors kill patients not only through well-characterized perturbations to their local environment but also through poorly understood pathophysiological interactions with distant tissues. Here, we use ...
pubmed.ncbi.nlm.nih.gov
And so fabulous to dine out with former postdocs Anne Classen @classenlab.bsky.social, Thomas Vaccari @vaccarilab.bsky.social and Lucy O’Brien. Many laughs, fond memories, and talk of bright futures for all of them. #EDRC2025
Honored to share stage with all the great plenary speakers at #EDRC2025. Exciting science and great vibes from Drosophila researchers worldwide – Let’s keep the American, Euro, and APAC communities coordinated and strong!
Beautiful paper from former student @dy-chen.bsky.social now postdoc in Zernicka-Goetz lab. Human embryos, stem cell models & mice: BM heterogeneity drives AP symmetry breaking. High-end microscopy, live imaging, physical modeling, mechanistic tests. Tour de force. www.nature.com/articles/s41...
Basement membrane perforations guide anterior–posterior axis formation - Nature Communications
Chen et al. show that in mice, extracellular matrix remodeling drives early migration of the anterior signaling center, establishing the body axis sooner than expected—a mechanism potentially conserve...
nature.com
Amazing and multitalented postdoc @ongkaty.bsky.social taking time out from writing her new paper with this generous initiative. #genetics, #CRISPR, #drosophila, hallmarks of #cancer and more. For a great cause; support @flybase.bsky.social!
Katy Ong@ongkaty.bsky.social · last yr.All proceeds from my #sciart Etsy shop will now be donated to @flybase.bsky.social . Due to fed cuts, this beloved resource that I use daily has lost it's funding, and I'm helping in my small way. Now's a good time stock up on #STEM & #drosophila gifts & swag! www.etsy.com/shop/Picosti...
All proceeds from my #sciart Etsy shop will now be donated to @flybase.bsky.social . Due to fed cuts, this beloved resource that I use daily has lost it's funding, and I'm helping in my small way. Now's a good time stock up on #STEM & #drosophila gifts & swag! www.etsy.com/shop/Picosti...
Happy to share a new publication: an introduction to comparative oncology in @natrevcancer.nature.com. Thanks to the leaders in the field for welcoming me as an invertebrate researcher. rdcu.be/etKdN
Advancing cancer research via comparative oncology
Nature Reviews Cancer - Comparative oncology combines evolutionary biology, ecology, veterinary medicine and clinical oncology to better understand cancer, for example, by identifying the molecular...
rdcu.be
New paper from superb postdoc Hui-Yu Ku about how proteases pattern extracellular matrix to precisely sculpt an organ. She will soon be an independent PI at National Yang-Ming University in Taiwan, expanding to study how ECM regulates egg activation. Congratulations! www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
pnas.org
Thursday, May 22 from 1 – 2:15 pm ET, Wu-Min Deng, @perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Register for free to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
Congrats to MCB's Diana Bautista and David Bilder for being named as AAAS Fellows @aaas.org! @bilderlab.bsky.social 👏 🎉https://news.berkeley.edu/2025/03/27/seven-faculty-members-named-fellows-of-american-association-for-the-advancement-of-science/
American Association for the Advancement of Science@aaas.org · last yr.Congratulations to the new 2024 AAAS Fellows class! They are a distinguished cadre recognized for their achievements across disciplines, including research, and teaching. www.aaas.org/news/aaas-we...
#Drosophila community: Dr. Istvan Ando has generously donated his invaluable anti-hemocyte monoclonal Abs to the #NIH-founded public repository @dshb-antibodies.bsky.social in #Iowa. We’ve tested several of them and they look great. See the🧵 for details. (1/5)
Thursday, January 30 from 1 – 2:15 pm ET, Wu-Min Deng, @perrimonlab.bsky.social and I will discuss fly cancer models during a #BeyondMammals webinar held by the NCI. Join to hear some of the many ways that Drosophila can contribute to #CancerResearch. events.cancer.gov/dcb/beyond-m....
Part of our lab studies #Drosophila cancer models. Delighted to announce ‘Beyond Mammals: Exploring Cancer Models” webinar held by NCI, hopefully in advance of funding opportunities. I’m speaking with @perrimonlab.bsky.social and others incl #Zebrafish and #Celegans PIs. Registration free.
Beyond Mammals: Exploring Cancer Models Webinar Series (Overview) | Events Registration
Overview The Beyond Mammals: Exploring Cancer Models series will feature three webinars, each focused on one non-mammalian animal model and its applicability to cancer research. Each webinar will high...
events.cancer.gov
Hosted a joint lab retreat with @LOBrienLab. Shared lots of science, some lore, and a bit of history, and introduced the Stanford folks to some of the joys of Berkeley.
New lab preprint —longtime project finished in Hong Kong by new investigator @Jung_Kim_PhD. www.biorxiv.org/content/10.1...
Now accepting applications- come join us in Berkeley! #Drosophila #Celegans careerspub.universityofcalifornia.edu/psp/ucb/EMPL...
@bilderlab@bilderlab.bsky.social · 2y agoWe are hiring a research technician for June here in Berkeley. Great for a post-bac interested in genetics, development or cancer biology. bilderlab.berkeley.edu Will update w/ official posting but feel free to reach out now, esp. candidates w/ model organism experience #drosophila. Please RT.
We are hiring a research technician for June here in Berkeley. Great for a post-bac interested in genetics, development or cancer biology. bilderlab.berkeley.edu Will update w/ official posting but feel free to reach out now, esp. candidates w/ model organism experience #drosophila. Please RT.
The Interactive Fly (www.sdbonline.org/sites/fly/ai...) is a guide to fruit fly development. It describes the literature of over 1,700 genes, dealing with developmental pathways and gene regulation. Sections include Drosophila as a model for human diseases, evolutionary biology, and neural circuits
Thomas Brodsky has arrived on Bluesky! Tom runs The Interactive Fly website and tirelessly surveys the #Drosophila literature. He won one of the inaugural Drosophila Community Service awards last year. Please follow him, like his posts, and welcome him here!
The Interactive Fly@interactivefly.bsky.social · 3y agoPrasad, D., Illek, K., Fischer, F., Holstein, K. and Classen, A. K. (2023). Bilateral JNK activation is a hallmark of interface surveillance and promotes elimination of aberrant cells. Elife 12. elifesciences.org/articles/80809
Nice @berkeleyMCB turnout tonight for @nkwhiteman.bsky.social 's triumphant talk about his book 'Most Delicious Poison'! @gastrulateordie Don Rio Georjana Barnes @DavidGDrubin @Choano_Lab n/s @danfeldman.bsky.social @mfeller.bsky.social @nickingolia @lianafaye.bsky.social Sabeeha Merchant
another awesome @bilderlab alumni talk. @d_y_chen, former @berkeleyMCB PhD, visits to describe his exciting work in @ZernickaGoetz lab and catch up with @MeganMartikPhD and @gastrulateordie. When he heads for the job market, grab him!
from @CajulaoJan: Fun @bilderlab outing at the ballpark last night! So far, the @SFGiantshave a 100% win rate whenever the lab is at the game😉😉
At group meeting this week, we introduced the three @bilderlab expat postdocs (Hui-yu Ku, Yoshiki Sanai, Stephan Gerlach) to good old American #Twinkies. Check out the before and after.
