UC Berkeley MCB

@berkeleymcb.bsky.social

Molecular & Cell Biology (MCB) Department at UC Berkeley | curiosity driven basic research, education, training and a commitment to public service. 🧪🐻 mcb.berkeley.edu/

Thrilled to share our collab led by Grace Hibshman with the Shipman lab! Type IX retron-Kva2 structure reveals phage detection via an HTH fold, not a primary sequence. We computationally designed triggers that program bacteria cell death, pointing toward designer antimicrobials.

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🧵 New paper alert! Today on bioRxiv, we show how a microtubule (MT) associated protein, MTCL1, links 2 regulatory layers: mechanical MT stabilization and writing of then tubulin code. A multi-lab effort driven by Juan Perez-Bertoldi and Julie Dang spanning atoms to organisms. 1/n

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