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Carlos A. Sánchez León

@carlosasleon.bsky.social

In vivo electrophysiology+2P calcium imaging. Postdoc at UCLA. Neuroscientist and gamer. Trying to understand how the brain works while enjoying the journey.

41 Posts95 Follower171 Folgt
Julio Lleonart@juliolleonart.com · last wk.

Con nombres y apellidos, partido al que pertenecen, qué votaron y cuántas viviendas e inmuebles tienen según las declaraciones de bienes y rentas publicadas en la web del Congreso. Nombres para la infamia.

Carlos A. Sánchez León@carlosasleon.bsky.social · 4w ago

PREPRINT 🚨 You know that feeling when you're jamming out to your favorite song (say, La Macarena 💃) and suddenly it skips, or a completely random remix drops out of nowhere? That everyday surprise tells us something profound about how our brain works! 1/24

El Abrazo del Oso Podcast@elabrazodeloso.bsky.social · last mo.

En El Abrazo estamos recuperando los primeros episodios remasterizados de la historia de la filosofía de Francisco J. García, empezamos con la antigua Grecia hasta la Edad Media: go.ivoox.com/rf/179141278 👇

Historia de la filosofía: Grecia y la Edad Media - El Abrazo del Oso Podcast - Podcast en iVoox

Escucha este episodio de El Abrazo del Oso Podcast gratis en iVoox. ¿Qué significaba buscar la verdad en la antigüedad? Desde el paso del mito al logos en la Grecia clásica hasta la compleja relación ...

go.ivoox.com

El Aprenditivo - Sorbitos de cultura@elaprenditivo.bsky.social · 5mo ago

En @elaprenditivo.bsky.social hablamos de neolengua, un concepto que ya aparecía a menudo en las distopías de ciencia ficción y que está muy presente en nuestras vidas. ¿Lo has escuchado ya? elaprenditivo.com/podcast/neol... #ElAprenditivo #Podcast #SorbitosdeCultura #ElAbrazodelOsoProducciones

Neolengua: desinstalando tu pensamiento crítico - El Aprenditivo - Podcast

Hoy en nuestro podcast hablamos de neolengua

elaprenditivo.com

Daniel Martínez@dmartimarti.bsky.social · last yr.

Excited to share our latest work at Cabreiro lab! Chemotherapy modulation by a cancer-associated microbiota metabolite www.cell.com/cell-systems... Here's what we discovered 🧵

Chemotherapy modulation by a cancer-associated microbiota metabolite

Martinez-Martinez et al. combine a host-microbe-drug-nutrient screen with multi-omics to reveal how the cancer-associated microbiota modulates chemotherapy. They identify 2-methylisocitrate, a microbi...

cell.com

Castuolízate@castuolizate.bsky.social · last yr.

📜 Hace hoy 142 años, Badajoz amanecía tomada por militares republicanos. Un pronunciamiento olvidado intentó restaurar la República desde el corazón extremeño. Aquí va la historia de una ciudad sitiada por ideales. 🧵Hilo🧵

Javier Márquez Ruiz@translationalbrainstim.com · last yr.

🧵1/ 🚨 New preprint out! We investigated how cerebellar transcranial direct current stimulation (Cb-tDCS) modulates sensory processing both locally in Crus I/II and distally in primary somatosensory cortex (S1) in awake mice. 📄 www.biorxiv.org/content/10.1...

Cerebellar tDCS differentially modulates sensory inputs in somatosensory cortex and cerebellum

Cerebellar transcranial direct-current stimulation (Cb-tDCS) is a promising tool for non-invasive modulation of cerebellar activity and has been proposed for the treatment of cerebellum-related disord...

biorxiv.org

Conchi Lillo@conchilillo.bsky.social · last yr.

Como hay gente que cree que es un truco o que os os estoy engañando, aquí tenéis un frame del vídeo. Mide las rayas de colores, de un extremo a otro (sin tener en cuenta las puntas de flecha). Cualquiera de ellas. Son todas iguales, compruébalo

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Conchi Lillo@conchilillo.bsky.social · last yr.

¿Tienes el cuerpo para una #ilusiónóptica? En este GIF parece que las líneas verticales azules y rojas cambian de tamaño, generando esa sensación de movimiento. Pero fíjate bien, su longitud no cambia, es fija. Lo que ocurre es que las puntas de flecha cambian de orientación de forma acompasada 😜

Dan Goodman@neural-reckoning.org · last yr.

Very happy to see this message that science publishers are not only a waste of money, but are actually distorting the scientific process itself, slowing down progress. This has been the key argument for me for a while. The waste of resources is bad, but the distortion of science is unforgivable.

George Currie@georgealfredcurrie.bsky.social · last yr.

Does publishing serve science or is science serving publishing? Damian Pattinson and I (@elife.bsky.social) argue scientific publishing has evolved into a system that, rather than facilitate scholarly communication, distorts and dictates it. onlinelibrary.wiley.com/doi/10.1002/... #OpenScience

Screenshot of article summary of: Toward Science-Led Publishing by Damian Pattinson, George Currie published as an opinion piece, in Learned Publishing Summary The current dynamic of scholarly publishing prioritises the wants of the publishing industry over the needs of the research community. This article explores this theme through the lens of ‘publisher-led science’ as a description of our current status quo, and through ‘science-led publishing’ as an improved future state. We argue that financial motivations central to most publishing distort how research is presented, how it is assessed and even what research is undertaken, leading to a system that hinders, rather than facilitates, scientific progress. We propose three elements of a science-led publishing approach that would accelerate research communication, incentivise collaboration between authors, editors and reviewers, and create a more transparent and equitable research landscape. We believe that research funding and research assessment are two of the primary levers for wider change in research and research culture and consider the future purpose of scholarly publishing in a world where these proposals have been widely adopted.
ZeigerLab@zeigerlab.bsky.social · last yr.

Really cool new science from the Portera-Cailliau lab on the neural circuit basis of social touch avoidance in a mouse model of Fragile X Syndrome. link.springer.com/article/10.1...

A reduced ability to discriminate social from non-social touch at the circuit level may underlie social avoidance in autism - Nature Communications

Social touch is critical for communication to impart emotions and intentions. However, certain autistic individuals experience aversion to social touch. Here, we used Neuropixels probes to record neur...

link.springer.com

Javier Guallar@jguallar.bsky.social · last yr.

La neurociencia de la desinformación @theconversation.com ttps://theconversation.com/la-neurociencia-de-la-desinformacion-255121?utm_medium=article_clipboard_share&utm_source=theconversation.com

La neurociencia de la desinformación

¿Cómo decide nuestro cerebro si compartimos o no desinformación? Una investigación reciente relacionada con los circuitos neuronales sugiere que la desinformación cumple una función social, y que comp...

theconversation.com

Carlos A. Sánchez León@carlosasleon.bsky.social · last yr.

Finally out! Check my previous thread for a quick look: bsky.app/profile/carl... In @elife.bsky.social: Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice doi.org/10.7554/eLif...

Somatodendritic orientation determines tDCS-induced neuromodulation of Purkinje cell activity in awake mice

The neuromodulatory effects of cerebellar tDCS depend on Purkinje cell somatodendritic orientation relative to the electric field, revealing a key factor for optimizing stimulation protocols and compu...

doi.org

Carlos A. Sánchez León@carlosasleon.bsky.social · last yr.

PREPRINT🚨Ever wonder how electrical⚡️ stimulation of the brain🧠modulates neuronal activity? Are you working with brain stim and variability makes you want to smash your pc and go to a mountain to grow tomatoes? Are you a family member or a friend who really appreciate me? 1/13