Anyone at #PlantBio2026 want to get out for a run during the conference?
Charlie Hale
@charleshale.bsky.social
PhD student in the Buckler Lab at Cornell. Genomics, evolution, agriculture.
We used genomic LLMs to find 330 genes with repeated functional shifts as grasses adapted and diversified. Great work by Sheng-Kai Hsu to make cross-species trait mapping tractable across 700+ complex genomes. www.biorxiv.org/content/10.6...
Convergent genome- and gene-level constraints shape repeated environmental adaptation in grasses
Grasses (Poaceae) dominate terrestrial ecosystems and sustain global food security, yet the genomic principles enabling their repeated adaptation to extreme environments remain unresolved. Combining d...
biorxiv.org
I'm hiring a postdoc to lead sedimentary aDNA reconstructions of alpine plant biodiversity as part of a broader project exploring the mechanisms of alpine plant resilience. Come join a collaborative team working in beautiful places! Bonus: postdocs at UMaine are unionized!
Postdoctoral Research Associate
The University of Maine is a community of more than 11,900 undergraduate and graduate students, and 2,500 employees located on the Orono campus, the regional campus in Machias, and throughout the stat...
fa-ewca-saasfaprod1.fa.ocs.oraclecloud.com
Postdoc in evolutionary genetics with @mbhufford.bsky.social isu.wd1.myworkdayjobs.com/IowaStateJob...
Postdoctoral Researcher - Evolutionary Genomics and Population Genetics
Position Title: Postdoctoral Researcher - Evolutionary Genomics and Population Genetics Appointment Type: Post Doc/Trainee Job Description: Summary of Duties and Responsibilities: We are seeking a Pos...
isu.wd1.myworkdayjobs.com
www.biorxiv.org/content/10.6... "TSS-proximal TFBSs are implicated in rapid, tissue-wide transcriptional stress responses....distal upstream regions contain conserved TF clusters that overlap rare cell type-specific accessible chromatin"
biorxiv.org
American climate science is losing federal support right when we need it most. Project Drawdown is stepping up: launching the Climate Science Serving America Fellowship for early/mid-career PhD scientists to do good science that does good. 🗓️ Apply by April 17 👉 https://bit.ly/4kx2J1Q
Hale et al. analysed >500 grass genomes to support a “stable motifs, variable binding sites” model of cis-regulatory evolution that involves turnover of thousands of individual binding sites while preserving TF binding preferences. 🔗 doi.org/10.1093/molbev/msaf324 #evobio #molbio #PlantSky
Widespread turnover of a conserved cis-regulatory code across 589 grass species
Abstract. The growing availability of genomes from non-model organisms offers new opportunities to identify functional loci underlying trait variation thro
doi.org
I wrote in the most recent issue of Arnoldia about using @inaturalist.bsky.social and, more generally, about the continuing role of natural history in motivating questions in evo bio + my excitement about community science for unlocking new scales of analysis: arboretum.harvard.edu/arnoldia-sto...
Year 1 data on congestion pricing in Manhattan… * Vehicle traffic: -11% * Foot traffic: +3.4% * Storefront vacancy: -0.9% * Pollution: -22% * Revenue for mass transit: $548M So YES this has been a huge success.
Our paper is out in MBE! doi.org/10.1093/molb... We tracked TF binding site evolution across 589 grass species, and found that while binding preferences are pretty stable over 80 million years of evolution, individual binding sites have turned over a lot. Thread here: bsky.app/profile/char...
New preprint from my PhD! How cis-regulatory evolution shaped grass diversification worldwide www.biorxiv.org/content/10.1... We looked across 589 (!) grass species to ask: — What regulatory changes enabled grasses to adapt? — How can this inform crop breeding for resilience? Here’s what we found:
"cis-regulatory evolution involves turnover of thousands of individual binding site instances while largely preserving transcription factors’ binding preferences." From: academic.oup.com/mbe/advance-...
Widespread turnover of a conserved cis-regulatory code across 589 grass species
Abstract. The growing availability of genomes from non-model organisms offers new opportunities to identify functional loci underlying trait variation thro
academic.oup.com
Identification of Freezing Tolerance QTLs in Tripsacum dactyloides Using Open-Pollinated Bulk Segregant Analysis https://www.biorxiv.org/content/10.64898/2025.12.10.693030v1
Made a site comparing the sizes of living things :) The great Julius Csotonyi spent 5 months painting over 60 illustrations for the site, no ai used > neal.fun/size-of-life/
Are you planning to attend Botany 2025? Consider applying to be a PLANTS mentor! You'll be paired with another mentor to help your mentee network, comprehend talks, and discuss grad school and careers, all while making them feel welcome in the botany community. (1/2)
Lineage-specific evolution of regulatory landscapes in polyploid plant and its diploid progenitors https://www.biorxiv.org/content/10.64898/2025.12.04.692133v1
Super proud of @alyssa-phillips.bsky.social 's paper, now out on biorxiv! She resolves the origin(s) of polyploid big blue-stem, a dominant species in the midwest tall-grass prairie. Her common garden analysis also informs on environmental adaptation and hints at the impacts of polyploidy.
The origins and adaptive consequences of polyploidy in a dominant prairie grass
Polyploidy is ubiquitous across North American prairies, which provide essential ecosystem services and rich soil for agriculture. Yet the mechanism driving polyploid abundance is unclear. Multiple hy...
biorxiv.org
Available now in @asn-amnat.bsky.social ! Taking on some big-scale natural history: processed >40k @inaturalist.bsky.social images of Monarda fistulosa using computer vision to query for flower presence and phenotype flower color: doi.org/10.1086/739413
High-throughput iNaturalist image analysis reveals flower color divergence in Monarda fistulosa | The American Naturalist: Vol 0, No ja
doi.org
New preprint out today! A really fun collaboration with @shchurch.bsky.social and Robin Hopkins in which we study flower color variation in Monarda fistulosa using iNaturalist data. We process >40,000 images and use them to phenotype flower color in >16,000 observations: doi.org/10.1101/2025...
To quote my friend @drkatemarvel.bsky.social, climate change won't make humanity extinct but we can do better than "not extinct". Raise your standards people!
We are seeking speakers for #pag33 hosted in San Diego: Jan 9th at 10:30am. Talk to us about your current/planned efforts to develop genomic resources for threatened/endangered species! @ebpgenome.bsky.social - hosted by @uconneeb.bsky.social @nanoporetech.com Abstracts by Oct 27th! 🧬 🦜 🌱 🐛 🐢
Most public transit systems depend largely on fare revenue to fund basic operations, but ridership never recovered after the pandemic. I wrote about 3 major transit systems that are facing a fiscal cliff, and the somewhat lackadaisical political response to the crisis. heatmap.news/politics/chi...
Yun et al. leveraged RNA-seq data to model gene expression variation in the grass Brachypodium distachyon and its response to soil drying, identifying genotypic, environmental, and G×E effects on physiological, metabolic, and gene expression traits. 🔗 doi.org/10.1093/molbev/msaf218 #evobio #molbio
@prereview.bsky.social is a great model for broadening participation in the review process!
Community Reviews are science in real time! Check out this new and recent example of open feedback in action: Hale et al.’s preprint got reviewed by a community-organized group through PREreview and then the authors replied to it. 📄 doi.org/10.1101/2025... #OpenScience #Preprints #CommunityReview
Our paper showing that variation in transcription factor binding sites underlies the majority of additive genetic variance for phenotypic variation in maize is finally out! Sadly they didn't use our suggested cover image below (made by the inimitable Andi Kur). www.nature.com/articles/s41...
SPEECHLESS duplication in grasses expands potential for environmentalregulation of stomatal development https://www.biorxiv.org/content/10.1101/2025.07.29.667563v1
"We found that TF orthologues from distant species retain nearly identical binding preferences, while on the same timescales the gain and loss of TFBSs are widespread." From: www.nature.com/articles/s41...
Recruitment, rewiring and deep conservation in flowering plant gene regulation - Nature Plants
A highly scalable approach is used to generate 3,000 genome-wide maps of transcription factor binding in ten flowering plants, along with multi-species single-nucleus RNA-seq atlases. Together, the re...
nature.com
Conservation of chromatin states and their association with transcription factors in land plants https://www.biorxiv.org/content/10.1101/2025.07.12.664529v1
So grateful to be one of the 500+ early-career scientists returning to their roots this month. The SNAP team behind this campaign has been such a blast to work with! @snapcoalition.bsky.social Check out my piece in the Marietta Daily Journal, as well as other national coverage: bit.ly/3HXlfB4
Graduate Students Push Back Against Science Funding Cuts
Hundreds of graduate students are writing to their hometown newspapers to defend their research, as the Trump administration drastically reduces science funding.
bit.ly
Neuroscientist Erin Morrow writes, “Wellstar Cobb Hospital is where science saved my life…Six months later, I walked across the graduation stage at Emory. My happy ending wouldn’t have been possible without decades of U.S. research” 🧪🏠 @erinmorrow.bsky.social www.mdjonline.com/opinion/well...
I just like to post these data from time to time to puncture the mythological aura of mid 20th c protests. They were less popular than pretty much any 21st c mass action & people criticizing them used the same lines. Protest is about people coming together, shaping narratives, & building power.
We're excited to share PlantCAD browser tracks: a new, unpublished dataset integrating AI techniques for plant genome analysis. Explore it here: github.com/andorfc/Plan... We welcome the community's feedback and innovative use cases for this data!
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate. www.philanthropy.cam.ac.uk/give-to-camb...