New preprint from our lab on bioRxiv: “Stoichiometric transcription factor partnerships control GABAergic neuron fate allocation” www.biorxiv.org/content/10.6... A great collaboration with @annrosebright.bsky.social, Connor Lynch, @chr-mayer.bsky.social, and many others.

Stoichiometric transcription factor partnerships control GABAergic neuron fate allocation

Combinatorial transcription factor (TF) codes specify neuronal fates, yet how quantitative differences in interacting TFs shape these decisions remains unresolved. We address this in the developing ba...

biorxiv.org

Only a few weeks left to apply for our 4-year PhD position, using human brain organoids & multi-omic methods to study genes implicated in speech disorders. Application deadline 5 Jan 2026. Fellowship is embedded in the International Max Planck Research School. More info: www.mpi.nl/imprs-phd-fe...

📢 🚨 Technical Assistant Opportunity in Neuroscience 📢 🚨 Join us at @lmumuenchen.bsky.social and support research on how neural circuits 🧠 drive adaptive behavior! ⏳ Deadline: 15. November 2025 Learn more and apply: www.fens.org/careers/job-...

Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/

From RNA to evolution: Come join our next keynote lecture on the choreography of brain development by @debbysilver.bsky.social, Professor at Duke University! 📍September 15 at 11am in NQ105 in Martinsried Art by @somedonkey.bsky.social

New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social

Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics

Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...

biorxiv.org

New from the Bocchi Lab in Nature Communications: Cortical astrocytes arise from two distinct progenitor lineages with specialized roles. Glad my lab could support the lineage tracing part using TrackerSeq. Congratulations to @bocchiric.bsky.social and the whole team! www.nature.com/articles/s41...

Dual lineage origins contribute to neocortical astrocyte diversity - Nature Communications

Astrocytes display diverse molecular and functional features in the brain, but the developmental origins of this heterogeneity are not well understood. Here, the authors show that two separate progeni...

nature.com

Riccardo Bocchi@bocchiric.bsky.social · last yr.

🚨 First paper from the Bocchi lab out now in @natcomms.nature.com! We show that astrocytes in the cortex arise from not one, but two distinct progenitor lineages, each giving rise to specialized subtypes with distinct roles. Here the story📖 doi.org/10.1038/s414...

Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc! Multiple positions across multiple groups @mrc-lms.bsky.social Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇 lms.mrc.ac.uk/work/vacanci...

MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences

Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.

lms.mrc.ac.uk

Ventral telencephalic progenitor maturation is gated by developmental timing, revealing a distinct regulatory logic underlying the development of inhibitory neurons @annrosebright.bsky.social @flo-neuhaus.bsky.social aus.bsky.social, @chr-mayer.bsky.social www.nature.com/articles/s41...

Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice - Nature Neuroscience

Unlike cortical progenitors, ventral telencephalic progenitors retain the ability to generate diverse neuron types during neurogenesis. Here, the authors show that ventral telencephalic progenitor mat...

nature.com

Now out in @natneuro.nature.com: Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice. Congrats to first authors @annrosebright.bsky.social, Yana Kotlyarenko, @flo-neuhaus.bsky.social, and thanks to all collaborators! www.nature.com/articles/s41... 1/n

Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice - Nature Neuroscience

Unlike cortical progenitors, ventral telencephalic progenitors retain the ability to generate diverse neuron types during neurogenesis. Here, the authors show that ventral telencephalic progenitor mat...

nature.com

📢 Announcing the MOPITAS Autumn School on Spatial Transcriptomics Data Analysis – taking place November 12–14, in Munich. Don't miss this excellent opportunity to deepen your expertise in data science and multi-OMICS analysis - especially as a PhD student in the data science community.

some new posters #sciComm #sciArt #neuroskyence #neuroscience

Attended the Neurogenomics Conference @humantechnopole.bsky.social in Milan earlier this week. Impressive host institute and an inspiring environment. Thanks to the organisers for putting together a strong and engaging meeting. #NeuroGen25

Our group leader @chr-mayer.bsky.social is one of the awardees of the Simons Foundation Autism Research Initiative (SFARI) Pilot Awards for a novel research project on the role of genetic mutations in chromatin-modifying enzymes in the development of autism – Congratulations!! 🎉 🧠✨

Big thanks to #SFARI for supporting our research through a 2024 Pilot Award. This funding will help us explore how mutations in chromatin regulators ASH1L and SETBP1 impact the development of inhibitory neurons and contribute to autism spectrum disorders. www.sfari.org/2025/04/08/a...

SFARI | Announcing the Recipients of the 2024 Pilot and Pilot Progression Awards

The Simons Foundation Autism Research Initiative is pleased to announce funding for 23 projects as part of its 2024 Pilot and Pilot Progression awards.

sfari.org

Alert! Postdoc positions available - at least two. Interested in coming to Karolinska and work on adolescent development/schizophrenia? Have a background in neuroscience, functional genomics, computational analysis or spatial transcriptomics? Large data sets available for analysis. Get in touch!