I'm delighted to announce that the Pharma Proteomics Project will commence full-scale proteomic profiling of the UK Biobank in 2025. We have selected the Olink Proteomics Explore HT platform and Ultima Genomics UG 100 sequencers for this unprecedented study. www.ukbiobank.ac.uk/learn-more-a...

Launch of world’s most significant protein study set to usher in new understanding for medicine

ukbiobank.ac.uk

Association of polygenic scores for neuropsychiatric traits with self-reported professions based on analysis of 420k individuals from UK Biobank and Million Veteran Program. Look at the 'arts & design' category. Artistic talent comes at a cost--a piece of your mind :)

Could be combined in the future with a continuous sensor (implant) for real-time detection of proteins driving inflammation in high-risk individuals www.science.org/doi/10.1126/... @science.org

Active-reset protein sensors enable continuous in vivo monitoring of inflammation

Continuous measurement of proteins in vivo is important for real-time disease management and prevention. Implantable sensors for monitoring small molecules such as glucose have been available for more...

science.org

Here we tried to provide some objective views to the reoccurring discussion: pubs.acs.org/doi/10.1021/... The key is to understand the biases and factors causing the differences in the data. Those can include and do go beyond the antibodies.

The Circulating Proteome─Technological Developments, Current Challenges, and Future Trends

Recent improvements in proteomics technologies have fundamentally altered our capacities to characterize human biology. There is an ever-growing interest in using these novel methods for studying the ...

pubs.acs.org

Loved participating in the ‘Advancing Multi-Omics to the Clinic’ meeting in beautiful Sydney this week. Fascinating talks from several KOLs (see photos for Ruedi Aebersold’s revised Central Dogma of Biology) & lots of encouraging interplay between mass spectrometry and affinity-based proteomics.