Chris Wymant

@chriswymant.bsky.social

Infectious disease epidemiology w stat/math modelling, genomics. Senior researcher at the Pandemic Sciences Institute, Oxford. Likes global & one health, sustainability; animals count too. Vegan, flyingless. Views own. https://github.com/ChrisHIV/teaching

The soundtrack from your favourite video game may be good background music for working: it's backgroundy by design, familiar, and you've already trained your mind to ignore it while you concentrate on problem solving. YouTube has extended recordings.

After 15 years of reporting on infectious disease outbreaks, what continues to fascinate me about them is the challenge of making high-stakes decisions under uncertainty. The hantavirus outbreak on the MV Hondius is a perfect example My story in @science.org is here (and a thread to come): 🧪 #IDsky

What to do with the passengers on the cruise ship hit by hantavirus?

Past studies of Andes virus offer scant evidence on transmission risks, and have sparked debate

science.org

Scientists themselves determine what is valued within science. Yet we act as if beholden to external managers, bean-counters who confuse the production of papers with scientific progress. We don't have to find better ways to navigate the prison of metrics-driven scientific assessment.

Confused writing is usually a symptom of confused thinking. As we struggle to clarify writing, we clarify our thoughts. AI writing aids rob us of that struggle, leaving clean-looking text and thoughts still confused for lack of inspection. Writing is not just a product; it is a diagnostic tool.

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Virus genomics peeps: if you use samtools pileup to get base counts from files of mapped reads, you might want to switch off its calculation & use of 'base alignment quality'. I decided this was best for HIV, documented here (in 2019, better late than never) docs.google.com/document/d/1...

Testing samtools’ base alignment quality for HIV

Testing the appropriateness of samtools’ base alignment quality (BAQ) calculation for HIV Recap: BAQ calculates a per-base probability of being misaligned, converts that to a quality score, then repl...

docs.google.com