Interested in glycan-binding proteins in Immunity? Check out this review with Gabriel Rabinovich, @chrrademacher.bsky.social, and Mirta Schattner on this subject. www.annualreviews.org/docserver/fu...

Surprising discovery of a covalent activator of a C-type lectin! We identified the first covalent small-molecule activators of the human C-type lectin DC-SIGN. Instead of inhibiting glycan binding, two warheads increased DC-SIGN activity. Open access here: doi.org/10.1002/anie...

Covalent Activation of the C‐type Lectin DC‐SIGN

We introduce the first covalent activators of a C-type lectin. Using orthogonal functional assays, NMR, MS/MS, and computational modeling, we delineate mechanisms from a functional electrophile-first...

doi.org

Mittels Targeted Delivery können #Medikamente direkt am Bestimmungsort wirken. Ein Forschungsteam @univie.ac.at hat eine Methode entwickelt, mit der Immunzellen in der Haut zielsicher angesteuert werden können. @chrrademacher.bsky.social #scilog 💊 scilog.fwf.ac.at/magazin/ziel...

Targeted Drug Delivery ermöglicht zielsichere Medikamente

Mit Targeted Drug Delivery werden Immunzellen in der Haut gezielt angesteuert – so minimieren der Molekularbiologe Christoph Rademacher und sein Team Nebenwirkungen. Das eröffnet neue Therapieoptionen...

scilog.fwf.ac.at

Thanks to Ratmir Derdra, our #glycotime answer to "The risk of mirror life" appears now under the article in Science www.science.org/doi/10.1126/... With @glycoexpasy.bsky.social @laurakiessling.bsky.social @carolynbertozzi.bskyverified.social @molinarotony.bsky.social @dbojar.bsky.social and many

Confronting risks of mirror life

Broad discussion is needed to chart a path forward

science.org

and more... @glycosmos.bsky.social @glycocode.bsky.social @chrrademacher.bsky.social @ethangbaus.bsky.social and again more but bluesky handle found @glyconet.bsky.social @sib.swiss

@glycoexpasy.bsky.social · 2y ago

Thanks to Ratmir Derda we have an articulate reply to: www.science.org/doi/10.1126/... putting glycans back into the picture! @laurakiessling.bsky.social @anneimb.bsky.social @carolynbertozzi.bskyverified.social @molinarotony.bsky.social @dbojar.bsky.social @siglecdude.bsky.social

Thanks to Ratmir Derda we have an articulate reply to: www.science.org/doi/10.1126/... putting glycans back into the picture! @laurakiessling.bsky.social @anneimb.bsky.social @carolynbertozzi.bskyverified.social @molinarotony.bsky.social @dbojar.bsky.social @siglecdude.bsky.social

Confronting risks of mirror life

Broad discussion is needed to chart a path forward

science.org

We are hiring, please RT! #Postdoc in the @ERC_Research project #DORMATRIX, developing #advanced #3Dimaging of #cancer dormancy & #metastasis. Bioengineers, biophysicists, biologists, computer scientists or similar. @biogipuzkoa @Ikerbasque. More info👉 bit.ly/4gXLP96

Join the Molecular Drug Targeting Lab at the University of Vienna! I have a vacant postdoc position for a qualified candidate: either with a background in delivery technologies or immunology. jobs.univie.ac.at/job/Universi...

Hello, Bluesky community! Let our first post be a good news: CBDD researchers Geert-Jan Boons and Rob de Vries (@rpdevrieslab.bsky.social), together with researchers in ErasmusMC Rotterdam, were awarded an #ENW-XL from the Dutch Research Council. Stay tuned for #phd/#post-doc openings! #glycotime

Here is a brief summary of academic journals and news account. Please help me add more accounts to this list! go.bsky.app/hCfhqn

It was a great privilege to chair the ChemBio VII conference (www.chembiovii.es) held in Seville. The organizing committee worked very hard to make the meeting a success. Amazing contributions and discussions in Chemical Biology with colleagues, with the beautiful Seville as a backdrop.

🧬🧶 people, if you're interested in knowing a bit more about the molecules that your proteins simply act as scaffolding for, check out or starter packs and lists. go.bsky.app/QTL6EqT

Glycotime

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Still time to register to awsome Glycobiology Gordon Research Conference 2025. We have a fantastic line of speakers and this will be top #glycotime in Tuscany !! Register at www.grc.org/glycobiology...