🦠 More food ≠ more diversity! Researchers @ratzke-lab.bsky.social found that extra nutrients can actually reduce microbial diversity — efficient bacteria outcompete rivals instead of new niches emerging. 🧾Nature Ecology & Evolution www.nature.com/articles/s41... Press release shorturl.at/bH4De
Cluster of Excellence CMFI
@cmfi.bsky.social
“Controlling Microbes to Fight Infections” (CMFI) researchers from different disciplines elucidate the mechanisms of interaction between beneficial and harmful bacteria and the host. – University of Tübingen, funded by the German Research Foundation (DFG)
🎙️ TERRAnauts Kira Rehfeld & Andreas Schweiger join „Exzellent erklärt" to talk soils, plants and climate — and the one-of-a-kind field experiment „Diversitorium". 🎧 exzellent-erklaert.podigee.io (German Language) | terra-cluster.org #exzellenterklaert #TeamTERRA #podcast
Exciting upcoming EMBL Conference: Unlocking the Functional Diversity of Gut Microbiomes. 8–10 Dec 2026, EMBL Heidelberg & online. For researchers interested in gene function, microbial diversity, host–microbe interactions, and microbiome research. Save the date, submit an abstract, and register!
How can we harness the vast functional diversity of microbes on our planet? Join us at EMBL Heidelberg from 8–10 December 2026 to hear about ongoing efforts to decode gene function and organisation in human gut microbes, and to present your own research. www.embl.org/about/info/c...
You are an ambitious young scientist, on the verge to independence, in a research field related to our Cluster of Excellence @cmfi.bsky.social “Controlling Microbes to Fight Infections”? Join our vibrant, interactive scientific community in Tubingen. Repost and apply! www.nature.com/naturecareer...
Independent Junior Research Group Leaders (m/f/d) - Tübingen, Baden-Württemberg (DE) job with Eberhard Karls Universität Tübingen | 12858473
The Cluster of Excellence EXC 2124 “Controlling Microbes to Fight Infections” (CMFI) at the University of Tübingen invites applications for Indepen...
nature.com
We were delighted to welcome Humboldt Fellows to @unituebingen.bsky.social and to the Cluster of Excellence CMFI. Thank you to the @humboldt-foundation.de and all participating Fellows for the inspiring conversations and the vibrant Humboldt Network spirit. 💚 #AvHNet
Fellows from across the globe, three inspiring days: our network meetings bring together Humboldtians in German university towns. 💚 #AvHNet #Humboldtian More info: www.humboldt-foundation.de/en/apply/spo... @cmfi.bsky.social
#joboffer #Germany plz spread it I'm hiring a Junior leader (E13; 100% for 3-5 y) to start own independence w/ focus on #CryoEM SPA or ET Ideally 1-2y postdoc experience Plz get in touch, if you are interested in #Structural biology & #MicroBiochem @sfb1381.bsky.social @vaam-microbes.bsky.social
Not just bigger muscles: study reveals that strength training affects our gut health. Participants with greatest strength improvements show biggest changes in their gut microbiome. Authors Sven Nahnsen / Daniel Straub explain within just a minute ➡️ tinyurl.com/5bhjjaxj @unituebingen.bsky.social
Paper in a Minute - Daniel Straub, Sven Nahnsen, Resistance Training Reshapes the Gut Microbiome
YouTube video by CMFI - Cluster of Excellence
youtu.be
Why are most metabolites barely detectable in wild-type cells — biology or technology? A new study from the Link lab shows it's biology: cells actively maintain minimal metabolite pools to avoid unwanted effects. www.cmfi.uni-tuebingen.de/en/news-even...
📅 Save the Date – CMFI Conference 2027 Feb 17–19, 2027 📍 Tuebingen, Germany Confirmed speakers: Benoit Chassaing · Eran Elinav · Neha Garg · Kiran Patil · Bertrand Routy · Nina van Sorge Subscribe to stay updated and join us in Tuebingen: www.cmfi.uni-tuebingen.de/en/cmfi2027
I'm excited to share our paper on how infected #macrophages promote #biomechanical alterations in #endothelia to transmigrate, published in @cp-cellreports.bsky.social! Thanks to all contributors, @sergemostowylab.bsky.social and @cmfi.bsky.social for the support. Here: www.cell.com/cell-reports...
Listeria-infected macrophages promote biomechanical alterations in endothelial cell monolayers for transmigration
Intracellular pathogens like Listeria exploit macrophages to cross endothelial barriers and spread systemically. Muenkel et al. show that exposure to infected macrophages weakens contractile forces wi...
cell.com
Largus Angenent, Professor für Environmental Biotechnology an der Universität Tübingen, erhält den Landesforschungspreis 2026, mit insgesamt 200.000 Euro der höchstdotierte Forschungspreis eines Bundeslandes. Herzlichen Glückwunsch! 👏 sohub.io/oal7 @mwk-bw.bsky.social #Landesforschungspreis
Great Microbiology Colloquium at CMFI today! Kirsten Küsel (@kuesellab.bsky.social @microverse.bsky.social) shared insights on the groundwater microbiome, plus Kyle Mason-Jones (@unituebingen.bsky.social) on soil bacteriophages. Thanks to all for great talks and discussions!
Great colloquium today! Guest speaker @pdersch.bsky.social showed how 𝘠𝘦𝘳𝘴𝘪𝘯𝘪𝘢 reprograms neutrophils during infection, causing severe inflammation and @effiebastounis.bsky.social how 𝘓𝘪𝘴𝘵𝘦𝘳𝘪𝘢 hijacks immune cells to spread. Key findings for fighting pathogens! #Microbiology #InfectBiology #BioMech
🦠🧫 a collaboration with the Institute for Tropical Medicine in Tübingen and CERMEL in Gabon @cmfi.bsky.social
Happy to share this paper by doctoral student Mirabeau Mbong Ngwese who assessed gut microbiome associations with soil transmitted parasites for adults and kids in Gabon and corroborated findings with data from other studies from Africa www.tandfonline.com/doi/full/10....
🎥 New series: Paper in a Minute! CMFI researchers explain key findings from recent publications in under 60s. Ep. 1: Ana Rita Brochado @brochadolab.bsky.social on antifolate-triggered CBASS activation in V. cholerae. Watch: youtu.be/q3EErS28oMs?... #ERC #AMR @natmicrobiol.nature.com #scicomm
Paper in a Minute — Ana Brochado, Vibrio cholerae CBASS phage defence system. Nature Microbiology
YouTube video by CMFI - Cluster of Excellence
youtu.be
🎉 Congrats to @brochadolab.bsky.social @unituebingen.bsky.social on a €2M ERC Consolidator Grant for BacImmune-Decode, advancing our understanding of bacterial immunity to fight infections + AMR!! More: www.cmfi.uni-tuebingen.de/en/news-even... @erc.europa.eu #ERC #AMR #Microbiology #ScienceNews
🌍 World Antimicrobial Awareness Week 2025 🦠 Antimicrobial resistance threatens global health. Unnecessary antibiotic use accelerates resistance and makes infections harder to treat. Use antibiotics responsibly and help raise awareness. Act now! youtu.be/_Qy3aTKiVLE #WWAW2025 #AMR #GoBlue
WAAW - World Antimicrobial Awareness Week
YouTube video by CMFI - Cluster of Excellence
youtu.be
This was a large interdisciplinary effort together with the groups of Heike Brötz-Oesterhelt within the @cmfi.bsky.social Tübingen, and @mingxunwang.bsky.social at @ucriverside.bsky.social.
How do keratinocytes sense bacterial commensals or pathogens? @cmfi.bsky.social Here is our recent review: www.sciencedirect.com/science/arti...
Role of Formyl Peptide Receptor 2 and Toll-Like Receptor 2 in Skin Barrier Function and Atopic Dermatitis
The skin acts as a barrier against external threats and plays an important role in tissue repair. Skin cells, including keratinocytes, sense microbe-a…
sciencedirect.com
#Antibiotika stören das #Mikrobiom im #Darm und ebnen so den Weg für Erkrankungen. Das gilt allerdings auch für viele Nicht-Antibiotika, zeigt eine neue Studie von @ghammeranne.bsky.social und @jdlcz.bsky.social vom @lisamaierlab.bsky.social am @cmfi.bsky.social der @unituebingen.bsky.social.
Studie: Nicht nur Antibiotika stören das Darm-Mikrobiom
Studie unter Leitung der Universität Tübingen: Viele Nicht-Antibiotika schwächen die natürliche Schutzfunktion des Darms, sodass sich krankmachende Bakterien leichter dort ansiedeln können
healthcare-in-europe.com
A new doctor is born 😊🥳 Welcome with me Dr. Haffner, the first PhD student of the group after wonderful years @cmfi.bsky.social Michael published 8 articles & a review with 3 as 1st author.. www.science.org/doi/10.1126/... www.pnas.org/doi/10.1073/...
New paper from the group. Together with Chambers Hughes, Giovanni Vitale and our amazing collaborators, we developed a multiplexed chemical metabolomics workflow to assign functional groups in non-targeted LC-MS/MS data: www.nature.com/articles/s41... Behind the paper story: go.nature.com/45ljV4d
Enhancing tandem mass spectrometry-based metabolite annotation with online chemical labeling - Nature Communications
To improve annotation in non-targeted metabolomics studies, authors develop a Multiplexed Chemical Metabolomics (MCheM) platform, combining post-column derivatization with integrated data processing. ...
nature.com
How are bacterial transport machineries regulated by external cues? @brochadolab.bsky.social &co identify environmental chemicals that regulate #transporter transcription, identifying the TF Rob as a key modulator of #EffluxPump expression in #Ecoli #AMR @plosbiology.org 🧪 plos.io/46pUM9Q
Study finds #caffeine can weaken effectiveness of certain #antibiotics Substances from natural environment can trigger bacteria's alert systems – implications for future therapeutic approaches? Read the press release here: www.cmfi.uni-tuebingen.de/en/news-even... @unituebingen.bsky.social
Finally out! A small screen helps understand a little more about how E. coli regulates major transporters, and reveals how caffeine induces phenotypical antibiotic resistance. Huge thanks to collab @andrenmateus.bsky.social (Umeå) and Christian L. Müller (Munich)! journals.plos.org/plosbiology/...
It's finally out!🎉 We known that the #microbiome confers colonization resistance against #pathogens, we know that some meds 💊 affect gut microbes 🦠 So, do 💊 alter colonization resistance? It turns out that some do! If you wanna know more, check out our latest work www.nature.com/articles/s41...
nature.com
Seeing this published is even better than eating sweets! I am so happy and proud of whole @lisamaierlab.bsky.social, especially Lisa and @jdlcz.bsky.social who walked the funny/exciting/rocky road with me until the very end. Check it out! #science #microbiome #health www.nature.com/articles/s41...
Non-antibiotics disrupt colonization resistance against enteropathogens - Nature
Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of such drugs.
nature.com
Unexpected side-effect: how common medications clear the way for pathogens CMFI's @lisamaierlab.bsky.social @unituebingen.bsky.social show in @nature.com: many non-antibiotics weaken the natural protective function of the intestine. Press release: www.cmfi.uni-tuebingen.de/en/news-even...
The paper is definitely worth a read—and if you're curious for a glimpse behind the scenes of how the story developed, don’t miss this short blog post by Anne and Jacobo. communities.springernature.com/posts/silent...
This is work of many years and many wonderful people! 🧑🔬 Led by Anne Grießhammer @ghammeranne.bsky.social and me at the Maier lab @lisamaierlab.bsky.social in Tübingen @cmfi.bsky.social. Read the TL;DR and how the project and Lisa's lab grew hand in hand here: go.nature.com/3Ix8lu3
Research Communities by Springer Nature
Research Communities by Springer Nature provide a forum for all those interested in research to share the latest discoveries, news, and opinions.
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🚨 Naming Challenge: Help redefine the #glycopeptide family! 🏆Submit your idea & win 500 € + authorship credit Let’s rethink antibiotic classification—together! 🧬 Deadline: Sept 15, 2025 👉 docs.google.com/forms/d/e/1F... @nadineziemert.bsky.social #NameChallenge #NaturalProducts #Antibiotics
𝗠𝗶𝗰𝗿𝗼𝗯𝗲𝘀: 𝗞𝗲𝘆 𝗽𝗹𝗮𝘆𝗲𝗿𝘀 𝗶𝗻 𝗵𝘂𝗺𝗮𝗻 𝗵𝗲𝗮𝗹𝘁𝗵 The human microbiome—comprising trillions of microorganisms—interacts closely with our immune, metabolic, and nervous systems. It influences directly our health. On #WorldMicrobiomeDay, we celebrate the science that shows how much Microbes Matter.