We are pleased that our article on Ataxin-2 and the integrated stress response in C9orf72 ALS/FTD is finally published in full. A lot of hard work from members of the lab, including @comeflywithjo.bsky.social, and our collaborators link.springer.com/article/10.1...

Targeting the integrated stress response or Ataxin-2 alleviates neurodegeneration in PolyGR models of C9orf72 associated frontotemporal dementia and amyotrophic lateral sclerosis - Acta Neuropathologi...

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are fatal, early-onset neurodegenerative diseases. The most common genetic cause of FTD and ALS is a G4C2 hexanucleotide repeat ex...

link.springer.com

Excited to send biological models trump cards from the NC3Rs office for the first time! 🎉 Created by @comeflywithjo.bsky.social via our public engagement awards, the game sparks discussion on choosing research models and replacing animal use. 📦 Get your free pack: nc3rs.org.uk/3rs-resource...

Thanks to @comeflywithjo.bsky.social for sending us two packs of these cards for use in our public engagement activities! They look great - and we're looking forward to using them with school children to help unpack why and how we use different model systems here @cruk-mi.bsky.social

Jo Sharpe@comeflywithjo.bsky.social · 2y ago

Top Trumps - but make it science 🤓 I had the most fun designing these, and I've written about how you could use it in your outreach programme! I'm keen to spread the word to any educators/academics who might be interested - please share 🤗 @nc3rs.bsky.social thenode.biologists.com/biological-r...

Nice work, Jo/‬@comeflywithjo.bsky.social! I have linked the resource out on droso4public: droso4public.wordpress.com/resources/#T...

Resources

On this page we collate resources helpful for your practical public engagement, including films and literature providing background on Drosophila. Classifying these resources in meaningful ways is …

droso4public.wordpress.com

the Node@the-node.bsky.social · 2y ago

Check out the Trump cards designed by @comeflywithjo.bsky.social, featuring all kinds of research models, from fruit flies to sea urchins to organoids🪰🐸🐟 Get in touch with Jo if you'd like to use the cards as part of your teaching/ outreach activities! #DevBio #StemCells #STEMoutreach

💡 If you are an educator, science communicator or researcher involved in public engagement, this card game from @comeflywithjo.bsky.social can help you talk about how scientists choose the right biological model for their experiments and options to replace animal use.

Jo Sharpe@comeflywithjo.bsky.social · 2y ago

Top Trumps - but make it science 🤓 I had the most fun designing these, and I've written about how you could use it in your outreach programme! I'm keen to spread the word to any educators/academics who might be interested - please share 🤗 @nc3rs.bsky.social thenode.biologists.com/biological-r...

Check out the Trump cards designed by @comeflywithjo.bsky.social, featuring all kinds of research models, from fruit flies to sea urchins to organoids🪰🐸🐟 Get in touch with Jo if you'd like to use the cards as part of your teaching/ outreach activities! #DevBio #StemCells #STEMoutreach

Jo Sharpe@comeflywithjo.bsky.social · 2y ago

Top Trumps - but make it science 🤓 I had the most fun designing these, and I've written about how you could use it in your outreach programme! I'm keen to spread the word to any educators/academics who might be interested - please share 🤗 @nc3rs.bsky.social thenode.biologists.com/biological-r...

Planning some public engagement work? Get in touch with Jo for a set of her beautifully designed Top Trumps cards & use them to explain how different model systems are used in research! 🐭🪰🪱🧫

Jo Sharpe@comeflywithjo.bsky.social · 2y ago

Top Trumps - but make it science 🤓 I had the most fun designing these, and I've written about how you could use it in your outreach programme! I'm keen to spread the word to any educators/academics who might be interested - please share 🤗 @nc3rs.bsky.social thenode.biologists.com/biological-r...

Top Trumps - but make it science 🤓 I had the most fun designing these, and I've written about how you could use it in your outreach programme! I'm keen to spread the word to any educators/academics who might be interested - please share 🤗 @nc3rs.bsky.social thenode.biologists.com/biological-r...

Biological Research Trump Cards: from fruit flies to stem cells... who will come out on top? - the Node

In 2023 I was awarded a NC3Rs 20th Anniversary Public Engagement Award to develop and print a "Biological Research Trump Cards" game. I have now designed

thenode.biologists.com

One of my favourite moments of 2024 was getting a delivery of 100 packs of Biological Research Trump Cards. I designed them myself and printed them with funds from @nc3rs.bsky.social ... please get in touch if you are interested in using some for your outreach/ PPIE activities 😀

Extremely basic #FluorescenceFriday looking at some fluorescent beads 👀 Mesmerising. So circular. So perfect.

Big fan of Sheffield lab Christmas walks 🚶‍♂️ ⛰️

It's the same every year. My writing soundtrack.

Rainbow over SITraN this morning 🌄

Sunny snowy Sheffield ❄️ Before I nearly fell flat on my face multiple times on the way down the hill.