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@corrylab.bsky.social

Computational protein research group of Prof Ben Corry. We love molecular dynamics and all kinds of membrane proteins including ion channels, transporters and immune receptors ~Posts by group members

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ANU Research School of Biology@biologyanu.bsky.social · 4mo ago

Join us on campus & online on Thursday, 23 April 2026 at 1pm for a seminar by Dr Caroline Puente-Lelievre, Research Fellow from the School of Biological Sciences and Centre for Computational Evolution, University of Auckland. @corrylab.bsky.social Details: rb.gy/ik3ep3

BSB Seminar Series: Structural phylogenetics: tracing protein functions from origins to diversification

In this talk, I will show how combining phylogenetic inference, protein structure prediction, and ancestral sequence reconstruction opens new ways to investigate how protein functions originate and di...

rb.gy

@corrylab.bsky.social · 6mo ago

How does your immune system tell pathogenic RNA from your own, even though they’re made of the same stuff? Our latest paper with @gantierlab.bsky.social shows some self RNA act as an off switch preventing autoimmunity in the absence of pathogens. 🧬🔬⭐ www.nature.com/articles/s41590-026-02429-2

2′-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity - Nature Immunology

Here, the authors show that 2’-O-methylated RNA fragments from ribosomal RNA naturally block TLR7 and TLR8, helping to avoid avoid harmful self-RNA detection and autoimmunity.

nature.com

ANU Research School of Biology@biologyanu.bsky.social · 6mo ago

Join us on campus & online on Monday, 16 Feb 2026 at 1pm for a seminar by Ciara Wallis, PhD Candidate @corrylab.bsky.social! Details: biology.anu.edu.au/news-events/....

BSB PhD Exit Seminar: Mechanisms of membrane transport proteins borderline between transporters and channels

Throughout my PhD, I determined the transport mechanisms of two proteins that we show break the standard channel / transporter definitions and instead function as anion “chansporters” - proteins that exist somewhere on the spectrum between transporters and channels.

biology.anu.edu.au

@corrylab.bsky.social · 9mo ago

You cant focus on new priorities if you don't have people and funding to do the work. Let's keep the scientists we do have.

David Pocock@davidpocock.bsky.social · 9mo ago

Save the CSIRO Our national science & research agency is now facing more job cuts than under Tony Abbott Call on the Albanese Govt to fund the scientists & research we need to tackle big issues we face from climate to food security and everything in between www.davidpocock.com.au/save_our_csiro

@corrylab.bsky.social · last yr.

Excited to share John's new work in Nat Coms! We demonstrate how PfCRT, a polyspecific peptide transporter, turns into a drug transporter for antimalarials like chloroquine and why this causes a fitness cost for the malaria parasite (1/2) tiny.cc/PfCRT

@corrylab.bsky.social · last yr.

Bittersweet to announce the wonderful YC's final work in our lab. We are so proud of everything she's accomplished (incl. this beautiful study showing how the TAM complex facilitates lipid flow between the bacterial inner & outer membranes). We can't wait to see what you do next, Dr. Lin 🤩

YC Lin@yiechanglin.bsky.social · last yr.

1/ In my final project as part of the @corrylab.bsky.social, we show the bacterial TAM complex facilitates the spontaneous flow of phospholipids from the IM to the OM in MD simulations.. www.biorxiv.org/content/10.1101/2025.03.12.642747v1

Lorne Proteins@lorneproteins.bsky.social · last yr.

Anders ECR session Ruitao Jin: plant Ca ion channels. Mechanical gating of OSCA channels. 100s of subtypes sense and react to physical forces. Homodimers with protomer pore and cleft. Liposome inside-in structure. Membrane belt-MD avg position of lipid head group. Contribute to ion selectivity 🤩

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@corrylab.bsky.social · 2y ago

Excited to start the year with this paper with @elainetao.bsky.social. Using simulations we show sodium channel blocking drugs bind at many sites within the pore and fenestrastions rather than at a single distinct pose. @jgenphysiol.bsky.social @scienceanu.bsky.social #ionchannels hubs.la/Q031spy70

Drugs exhibit diverse binding modes and access routes in the Nav1.5 cardiac sodium channel pore

Tao and Corry investigate how the binding of sodium channel inhibitors to the Nav1.5 pore using simulations reveal promiscuous, polyspecific binding at the

hubs.la