(2/3) Highlights for today: 1️⃣ Welcome by Dra. Marta Vilaseca (@irbbarcelona.org). 2️⃣ Insights on scaling and democratizing spatial tissue proteomics with Dr. Fabian Coscia (@coscialab.bsky.social MDC Berlin, @mdc-berlin.bsky.social). 3️⃣ Pedro Cano (Bruker @brukerspatial.bsky.social).

Unique opportunity!! :-)

Sampurna Chakrabarti@amapruns.bsky.social · 4mo ago

We are looking for a postdoctoral scientist to work on challenging and exciting neuroproteomics problems. Close collaboration with @coscialab.bsky.social Apply: jobs.helmholtz-hzi.de/job/Braunsch...

Excited to share our new @natcomms.nature.com study with the @garyrlewin.bsky.social lab and @amapruns.bsky.social. Using deep visual proteomics, we created the first neuronal subset-resolved proteomic map of sensory neurons with potential implications for pain treatment. go.nature.com/481nr4R

Deep visual proteomics uncovers nociceptor diversity and pain targets - Nature Communications

Sensory neuron subtypes are defined by transcriptomics, but their proteomic identities remain unclear. Here, authors show distinct protein signatures of electrophysiologically defined nociceptors and ...

go.nature.com

Check out our latest preprint in collaboration with the @garyrlewin.bsky.social lab! We obtained the first subset-specific proteomes of pain sensing neurons!

Sampurna Chakrabarti@amapruns.bsky.social · 11mo ago

We present the first subset-specific proteomic signature of electrophysiologically-defined, pain-sensing neurons. One step closer to uniting function with molecules- one neuron at a time. Thanks to all who have contributed, especially @coscialab.bsky.social @garyrlewin.bsky.social #neuroscience

Excited to introduce openDVP — an open-source framework to bring deep visual proteomics to the broader research community! It includes: – A simplified fast-track pipeline for easy adoption – An AI-powered option for advanced image & spatial analysis 👉 BioRxiv: bit.ly/44SBuHu 👉 Github: bit.ly/4eR3IqK

Thrilled to share our latest preprint describing an optimized spatial tissue proteomics workflow for the preparation and analysis of >100 proteomes / day at high spatial resolution. Kudos to @melissaklingeberg.bsky.social 🥳 and big thanks to all our collaborators! bit.ly/3SCARw4

An ultrasensitive spatial tissue proteomics workflow exceeding 100 proteomes per day

Achieving high-resolution spatial tissue proteomes requires careful balancing and integration of optimized sample processing, chromatography, and MS acquisition. Here, we present an advanced cellenONE...

bit.ly

Our lab's newest preprint is out on deep spatial proteomics of ovarian cancer precursor lesions! We demonstrate how ultrasensitive discovery proteomics can shed light onto early carcinogenesis, uncover cell-of-origin signatures, and prioritize novel drug targets. bit.ly/41M7fke

Deep spatial proteomics of ovarian cancer precursor lesions delineates early disease changes and cell-of-origin signatures

High-grade serous ovarian cancer (HGSOC) is a devastating disease that is frequently detected at an advanced and incurable stage. Advances in ultrasensitive mass spectrometry-based spatial proteomics ...

biorxiv.org

Shout out to the organisers @jesperolsenlab.bsky.social, (Tina Ludwig) @baybioms.bsky.social kathrynslilley.bsky.social, Caroline May and Britta Eggers and the speakers @bonalditiziana.bsky.social, @coscialab.bsky.social, @kusterlab.bsky.social, @anamdv.bsky.social, @jsandow.bsky.social

Shabaz Lab@shabazlab.bsky.social · last yr.

The Brixen Proteomics Summer School speaker list has been finalised!. Lots of amazing science to be discussed! Big thanks to @eupaproteomics.bsky.social @msaid-de.bsky.social @thermofishersci.bsky.social @biognosys.bsky.social @ionopticks.bsky.social @evosep.bsky.social for support

Our selected speakers doe rhe different sessions are: Georg Kustacher - bioinformatics @coscialab.bsky.social single cell/spatial session Manuel Mayr - clinical proteomics Richard Seltema - structural Freddie Theodolou - non-human proteomics Jyoti Choudary - functional proteomics

"Innovations in Single Cell Omics" Berlin 5.12-13. Keynote Speakers: @shalinhnaik.bsky.social Pulin Li, and me! Invited Speakers: @emmanuel-saliba.bsky.social @mratz.bsky.social Barbara Grünwald Maria Colomé-Tatché Mohammad Lotfollahi @coscialab.bsky.social Teresa Krieger www.isco-conference.eu

ISCO - ISCO

isco-conference.eu

Wonderful group dinner tonight, #proudPImoment ☺️🫶

Next up at the @fogenomics.bsky.social proteomics stage, @ajbrenes.com talking about single-cell proteomics applied to neutrophils. Cool stuff!

Extremely happy that our Deep Visual Proteomics pipeline is one of the highlighted @naturemethods.bsky.social Spatial Proteomics approaches! 🥳 Congrats to the growing DVP team(s)! Making it broadly accessible & advancing it to the multiomics space is a key mission in our lab @mdc-berlin.bsky.social

Rita Strack@ritastrack.bsky.social · 2y ago

I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...