How do gene regulatory programs, cell-cell interactions & tissue patterning organise in space and time during human development? Zhang, Vandana, Greenspun & @shuibingchen.bsky.social review the spatial technologies — and organoid models — helping us find out 🧬🔬 shorturl.at/GGzfn

Dissecting human organ development using spatial technologies

In this review, Zhang et al. discuss recent advances in spatial omics and their applications to human development. They highlight how spatial profiling, combined with stem cell-derived organoids and c...

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Glia don't just "support" neurons - they sculpt circuits. Sakers, Sheehan, Xin, Schafer & Eroglu review 25 years of evidence showing how astrocytes, microglia & oligodendrocytes actively orchestrate synapse formation, pruning & circuit maturation 🧠 www.cell.com/developmenta...

Glia orchestrate neural circuit development

In this review, Sakers et al. discuss how astrocytes, microglia, and oligodendrocyte lineage cells actively regulate neural circuit formation, refinement, and stabilization. They propose that coordina...

cell.com

RNA modifications - noncanonical caps, m6A, and pseudouridine - form a dynamic regulatory layer governing RNA fate across plant and animal development. Chen, Hu, Jia, Yi & Zhu review their mechanisms, detection, and therapeutic potential 🧬 www.cell.com/developmenta...

Noncanonical caps, m6A, and Ψ RNA modifications in plant and animal development

In this review, Chen et al. discuss how three types of RNA modifications—noncanonical caps, m6A, and pseudouridine—regulate animal and plant development. Elucidating the underlying mechanism and funct...

cell.com

How do mechanical forces drive cancer progression? Ivaska, Sale & Yap review how tumours hijack epithelial mechanosignalling - from actomyosin tension and ECM stiffness to jamming–unjamming transitions - and what this means for therapeutic targeting 👉 shorturl.at/zBp2J

I had the chance to highlight some amazing #DevBio from @gcharras.bsky.social and @herveturlier.bsky.social for @natcellbio.nature.com this month! Check out my Research Highlight www.nature.com/articles/s41... and the original article in @cp-devcell.bsky.social www.sciencedirect.com/science/arti...

Interested in how plant stem cells can strive in the harshest environments? Read @thomasgreb.bsky.social and my review of plant stem cell robustness: doi.org/10.1016/j.de...

Stem cell-derived embryo models are imperfect, but @zernickagoetz.bsky.social & Sergio de la Rosa argue that's the point. When models stall or mispattern, they expose the signals, timing & tissue interactions essential for robust human and mouse development. 👉 www.cell.com/developmenta...

Our review on glial orchestration of neurodevelopment is online at @cp-devcell.bsky.social! Great fun working with Krissy Sakers and Pat Sheehan from the Eroglu and Schafer labs, and special thanks to first author Krissy for her tremendous work bringing this to fruition! www.cell.com/developmenta...

Glia orchestrate neural circuit development

In this review, Sakers et al. discuss how astrocytes, microglia, and oligodendrocyte lineage cells actively regulate neural circuit formation, refinement, and stabilization. They propose that coordina...

cell.com

Developmental Cell is 25 years old! 🎉 To celebrate, we commissioned a special set of Reviews & Perspectives spanning cell and developmental biology — tracing progress, revisiting open questions, and looking ahead: www.cell.com/developmenta...

Cell Symposia is now Cell Press Symposia. Our meetings have always been shaped by Cell Press editors—this name simply makes that connection clearer. Read more: http://dlvr.it/TSr7FK