Canadian VIGOUR Centre

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The Canadian VIGOUR Centre (CVC) is an academic research organization at the University of Alberta dedicated to enhancing cardiovascular health.

Among adults with CKD stage 4/5 or on dialysis, low-dose rivaroxaban did not lower cardiovascular risk but did raise major bleeding rates, supporting guideline caution in this group. ja.ma/3TgP0Tp

JAMA clinical trial summary: Low-dose rivaroxaban did not reduce cardiovascular events in 1458 advanced CKD patients (22.6% vs 20.7% for placebo), but increased major bleeding (8.8% vs 6.0%). Mean age 63. Trial across 90 centers worldwide.

We spoke with Justin Ezekowitz, MD, to discuss his recent analysis of the SODIUM-HF trial, which indicated that dietary salt limitations may only benefit patients at the lowest risk for heart failure, contrary to popular belief. Watch now:

Sodium Restrictions May Only Benefit Patients at Low Risk of HF, With Justin Ezekowitz, MD | HCPLive

Ezekowitz discusses his recent secondary analysis of the SODIUM-HF trial, highlighting the MAGGIC analysis data that implied a very limited benefit.

hcplive.com