Penicillin was not, in fact, the first antibiotic.

If you've lost a chicken in Northeast Seattle, she's safe with a neighbor (DM with breed and description) 🐓🐔🐣 #chickens #chickencoop #chickenkeeping #backyardchickens

STOP using ipTM for #AlphaFold PPI screens. * Artificially LOW when both full-length proteins have irrelevant, non-binding IDRs/domains. * If one protein is folded & other contains irrelevant IDRs or domains, the score is too HIGH bc of d0. * Use ipSAE or LIS. www.biorxiv.org/content/10.1...

Hello/goodbye C-17 low-level over Keechelus Lake, WA, seen from I-90

It's a common misconception that Reed College (in Portland, Oregon) has the only nuclear reactor operated by undergraduate students. In fact, though, the Idaho State and UNM reactors are also student-run

Quantian@quantian.bsky.social · 3mo ago

US universities genuinely are like “welcome to Tennessee Agricultural College in Bumfuck Nowheresville. We invented the modern potato and our facilities include a particle accelerator, nuclear reactor, and TOP500 supercomputer. Tuition is $12,000 for instate students and we have 40,000 of them”

Good opportunity to adopt a quarter system!

I cannot believe this is a real thing. If you are in Laurelhurst and are bothered by the helicopter noise from Seattle Children's Hospital to the degree that you think signing this petition is in anything other than unconscionable, move. You can afford it.

Laurelhurst Community Council Isn’t Sure Helicopters Need to Land Sick Kids at the Hospital  - The Stranger

This, the affluent North Seattle neighborhood will tell helicopters are quite the nuisance. Such a nuisance that a neighborhood group wanted to make sure the hospital wasn't landing flights on the hel...

thestranger.com

We're super excited to share MissAlignment: a new ML-based approach to reference-free tilt series alignment, spearheaded by @martenchaillet.bsky.social. We think it's going to make your cryo-ET life a lot better. Preprint: www.biorxiv.org/content/10.6... Code: github.com/warpem/miss-... 🧶 Thread:

Can we use #proteindesign to develop countermeasures before viruses cause pandemics? We describe the computational design of an ultrapotent and broadly neutralizing deltacoronavirus miniprotein in our latest work led by Nathan Avery @hhmi-science.bsky.social 1/12 www.pnas.org/doi/10.1073/...

How are host proteases promoting coronavirus entry into cells? Find out by reading our latest manuscript led by @mattmccallum.bsky.social Brett Case Jack Brown & @youngjunpark.bsky.social in collaboration with @msdiamondlab.bsky.social 1/19 www.nature.com/articles/s41...

TMPRSS2-mediated coronavirus spike activation and inhibition - Nature Structural & Molecular Biology

Here, the authors elucidate TMPRSS2 protease recognition of the SARS-CoV-2 spike S2′ cleavage site, revealing the molecular basis of activation of membrane fusion, and show that antibodies recognizing...

nature.com

Yay proportional editing is now available in the Coot 1 API (in the daily)! This alters the sphere of influence of dragged refinement, which helps a lot when making large adjustments - register shifts of helices, domain movements, etc. I've added in a little widget to set it in coot1-trimmings.

"Something about the air hits different today" - student getting off the bus (1st year?) It's Springtime in Seattle, welcome to the other side! 🌇

NASA solution: superparamagnetic resin dice (zero residual magnetism), electromagnetic game table activates when photodiodes occluded by dice CCCP solution: dice cup

Athalbert@athalbert.bsky.social · 4mo ago

Es una pequeña tirada para una mujer, un crítico para la humanidad. #lodelrolenelespacio #lodelrol

Fresh (after resting), Javanese anaerobic fermentation

The proteina-complexa paper is the 2nd this month suggesting that high K+E content, a staple of ProteinMPNN designs, is predictive of poor expression (the bits in bio benchmark paper showed a few weeks ago). In their case, they measure poor sequence recovery in phage display

I <3 you too King County Metro

"Submitting the AAM to PMC does not require payment to the publisher or publishing open access. Federal agencies have, by law, certain rights to products resulting from federal funding under the “Government Use License”... 1/2

Tim Lohman@lohman.bsky.social · 6mo ago

From my institution. The OVCR released guidance today re the 2024 NIH Public Access Policy, specifically the applicability of the Government Use License/Federal Purpose License: research.washu.edu/topics/publi...

🤘

Delnia Nazari@delnianazari.bsky.social · 5mo ago

Birthday treat to myself was a little timelapse in the cell culture🤭🎂🧫 Nothing professional, just capturing memories of my PhD and, I like how it turned out.🥹

I'm waiting for the bus, bunch of kids just drove through campus in an open top Model A, bumping music, no headlights (Actual Model A, a really fly restoration, all blue, historical plates)

There are right and left handed tubes in this bag and it's mildly disturbing 😨

Wave Interference, Ink on Yupo, 2026

Good to see the PhD lab is still following the rules

The new ChimeraX CubeNTube plugin allows erasing parts of maps using cube, cylinder, and custom shapes and has undo. Created by Tamino Cairoli. Available from ChimeraX menu Tools / More Tools....

Share a movie you incorrectly think no one else remembers 😇

Alex Merz 🇺🇸🇨🇦🇺🇦@merz.bsky.social · 5mo ago

Share a movie that no one else remembers that you regularly think about

I really like these

What speaks all languages, but has no voice? Would be silent, but has no choice? As old as the air, it spoke only when we did.

Pacific chorus frogs aptly named 🐸

FrontRangeWildflowers@frwildflowers.bsky.social · 6mo ago

Frog chorus in Santa Cruz off West Cliff Drive 🌿

The most important command IMO: help ChimeraX includes the online documentation in a built-in viewer. Guarantee you'll learn something useful if you read these three... help alias help functionkey help view

ChimeraX@chimerax.ucsf.edu · 6mo ago

ChimeraX cheat sheet brought to you by Alejandro Pereira. www.rbvi.ucsf.edu/chimerax/dat...

priviliged to be witnessing these amazing cellular vistas! makes you wonder about all the unknownwhat biology is being captured here!

My god man what's happened to you