Very important phase1/2 trial of a 6-valent group B strep vaccine. The vaccine was both safe and immunogenicity in pregnant and non pregnant persons. Sets the stage for ph3 studies. GBS sepsis is a major cause of neonatal sepsis causing 91,000 newborn deaths/yr. www.nature.com/articles/s41...
Maternal 6-valent group B Streptococcus vaccine in non-pregnant and pregnant females: a randomized phase 1/2 trial - Nature Medicine
A phase 1/2 study found maternal hexavalent 6 polysaccharide−protein conjugate group B Streptococcus vaccine (GBS6) to be safe and immunogenic and to have induced antibody responses to vaccine serotyp...
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