When another mouse goes from friend to foe, connections from the hippocampus to the amygdala strengthen. #neuroskyence By @natmesanash.bsky.social www.thetransmitter.org/social-behav...

Friend to foe: How the brain updates feelings toward others

A specific pathway reassigns emotional valence to a known mouse, while the hippocampus’s own representation of that animal’s identity remains stable.

thetransmitter.org

🧠🔬Really looking forward to joining the #FENS2026 in lovely Barcelona! The whole DeepEn team is excited to discuss holographic microendoscopy for deep brain imaging at Booth #64. Stop by for a chat—we'd love to meet you! #neuroimaging #microscopy #neuroscience

🧠🔬Really looking forward to joining the #FENS2026 in lovely Barcelona! The whole DeepEn team is excited to discuss holographic microendoscopy for deep brain imaging at Booth #64. Stop by for a chat—we'd love to meet you! #neuroimaging #microscopy #neuroscience

You ever get the feeling you may have slightly, massively overengineered something? Still need to add the electronics, but these should turn into some handy little Arduino-powered training rigs.

#fluorescenceFriday looking at cholinergic neurons and processes in 3 D with Chat in yellow and VAChT magenta by the @mind-western.bsky.social team and Ariel Burrowes

Happy #MicroscopyMonday everyone!🔬🧪 Today's stunning image comes from Lillian! The image shows the apical part of a 9-day old mouse cochlea with myosin7a ❤️ staining the hair cells, DAPI 💙 staining the nucleus and a ✨mysterious✨ green protein💚👀 #NeuroSkyence #HearingResearch

Come and join our lab! We have TWO fully funded PhD positions AND a paid field assistant opportunity in our Behavioral Ecology group @uni-goettingen.de & @primatenzentrum.bsky.social. Projects will be part of @rtg2906-curiosity.bsky.social & @sfb1528.bsky.social!! Details in thread. Please re-post!

Mini Matrix enables high-density 3D recordings in small animals, providing access to large neuronal populations for acute or chronic studies. 32–128 channels for rec & stim Automated, low-risk implantation Modular, customizable configurations Optogenetics-compatible

🎶Let’s dance…but make it light sheet. For #FluorescenceFriday, the team is looking at blood vessels in brilliant color🧠. Beautiful imaging by @mind-western.bsky.social, @shahrzadbahrampour.bsky.social, @nadiahaghbinphd.bsky.social, and Vladislav Novikov! When our science moves, it grooves. 🔬😎

Optical clearing & time-lapse fluorescent imaging of Live mouse Brain (up to 800 μm of depth)🤯 An acute olfactory bulb slice(P11) loaded with GCaMP6f (Ca2+ sensor) was imaged with #2PM at a depth of 150 μm during clearing with SeeDB-Live👹 #NatMethods 2026 www.nature.com/articles/s41...

@deepen-imaging.bsky.social will be exhibiting at the Bonn Brain Conference 23–25 March 2026 at #dzne #bonn. Come meet us to learn more about the latest developments in holographic microendoscopy and how you can use it to access deep brain regions. See you in Bonn! #Neuroscience #Neurotech

Glia in Focus 🔬 A series highlighting the beauty of glial cells. Confocal image (64x) of rodent brain tissue (P1) showing microglia (Iba1, magenta) near a CMV-infected microglial cell (green). Image: @Sarah Tarhini #GliaInFocus #Microglia #ConfocalMicroscopy #BrainDevelopment #ScienceArt

As Neurophotonics developers, we love learning about in vivo imaging directly from scientists. We’re recruiting 20participants for our in vivo imaging survey. ⏱️ ~10 min 🎁 Free neuron socks Work with in vivo animal imaging? Contact us at info@deepen-imaging.com. #neuroscience #microscopy#neuroimaging

As Neurophotonics developers, we love learning about in vivo imaging directly from scientists. We’re recruiting 20participants for our in vivo imaging survey. ⏱️ ~10 min 🎁 Free neuron socks Work with in vivo animal imaging? Contact us at info@deepen-imaging.com. #neuroscience #microscopy#neuroimaging

🚀 Excited to announce that I'm looking for people (PhD/Postdoc) to join my Cognitive Modelling group @uniosnabrueck.bsky.social. If you want to join a genuinely curious, welcoming and inclusive community of Coxis, apply here: tinyurl.com/coxijobs Please RT - deadline is Jan 4‼️

Lilian Weber@lilweb.bsky.social · 11mo ago

In other news, I am now a ✨ COXI ✨ (cognitive scientist in Osnabrück, Germany) www.uni-osnabrueck.de/en/campus-li... I'll be looking for PhD students & postdocs later this year, so watch this space if combining cognitive modelling, EEG & tFUS to study flexible cognition sounds exciting to you 🚀

#SfN25 is now over! Thanks to all the lovely people who came to our booth and shared their science stories with us! It was an inspirational week for DeepEn! Thanks to @sfn.org for an extraordinary meeting!

🧠📢 New preprint alert Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵 #neuroskyence #compneurosky

DeepEn is at NEUROSCIENCE 2025 #SfN25 ! 🧠🔬🌴 Come to our BOOTH #3027, check our microendoscope for deep brain imaging with sub cellular resolution and minimal tissue damage. And meet Hana, Tomas, Patrick and Jiri! #neuroimaging

I'm excited to join #SfN2025 next week. Stop by booth #3027 to connect and learn more about structural and functional imaging in-vivo anywhere in the brain! I’d love to hear about your research and ideas! Looking forward to meeting you there.

This new miBrain model from MIT has it all: 🧠 Neurons, microglia, oligodendroglia, astrocytes, pericytes, & brain microvascular endothelial cells ⚙️ Key features & functions of the human brain 👩‍👦 Specificity to individual donors 🧬 Customizability via gene editing 📈 Scalability for large projects

🧠What do neuroscientists think of DeepEn's holographic microendoscope? How can they use it to study learning and memory processes? Can it enable voltage imaging in deep brain structures to study processes behind neuronal firing? ⭐ Check the Nature’s article: www.nature.com/articles/d42...

High-resolution insights from the deep brain

Discover the world’s best science and medicine | Nature.com

nature.com

Excited to share we’ve been awarded the ERC StG 🎉 for our project ProSocial, studying neural mechanisms of prosocial behavior in health & disease. Huge thanks to my group for their amazing work & to great colleagues for their support! Positions opening soon—reach out if interested!

European Research Council (ERC)@erc.europa.eu · 11mo ago

📣 The ERC Starting Grant call results are out! Find out which early-career researchers will receive funding this year, what they will be investigating, where they will be based... plus lots of other #ERCStG facts & figures for 2025! ➡️ buff.ly/IsafuFh #FrontierResearch 🇪🇺#EUfunded #HorizonEurope

Are you the kind of neuroscientist who scripts analysis or can’t resist tinkering with hardware? At DeepEn we’re building a fluorescence microscope to image deep in the brain through a single optical fiber. Join us to hack the future of neuroimaging: #ScienceJob www.linkedin.com/jobs/view/42...

⏰ Reminder: The early bird registration and abstract submission for our 5th Day of Intravital Microscopy close on September 5! Don’t miss your chance to join us in Tübingen on 18–19 Sept. Secure your spot today! 👉 bit.ly/3IOlJtJ

5th Day of Intravital Microscopy - German BioImaging

Intravital microscopy (IVM) enables the observation and precise quantification of cellular processes within native tissue microenvironments, with resolutions unmatched by other techniques. This powerf...

bit.ly

Beautiful work!

Tomás Ryan@tjryan.bsky.social · 11mo ago

Updated (final) preprint below: www.biorxiv.org/content/10.1...

Fun collaborative work together with the amazing lab of @sophiesteculorum.bsky.social now published!

Sophie Steculorum@sophiesteculorum.bsky.social · last yr.

📢 🤩Excited to share our latest paper👃🧠! Huge thanks to the amazing first author @janice-bulk.bsky.social‬ and all co-authors, especially @andreas-t-schaefer.bsky.social and ‪@tobiasackels.bsky.social‬ 🙌! ‬‬ www.nature.com/articles/s42...

www.nature.com/articles/s41...

A mouse brain stereotaxic topographic atlas with isotropic 1-μm resolution - Nature

A stereotaxic atlas of the whole mouse brain, based on a Nissl-stained cytoarchitecture dataset with isotropic 1-μm resolution, achieved through continuous micro-optical sectioning tomography, promise...

nature.com

Hippocampal vasculature is so pretty 😍 (mouse hippocampus perfused with Tomato Lectin and cleared) #Neuroscience #Microscopy

Where does Alzheimer’s begin in the brain? Our study in @cp-neuron.bsky.social shows that the earliest amyloid-related neuronal dysfunction emerges selectively in deep cortical layers (layers 5/6), targeting fast-spiking parvalbumin interneurons via reductions in NPTX2. www.cell.com/neuron/fullt...

Selectively vulnerable deep cortical layer 5/6 fast-spiking interneurons in Alzheimer’s disease models in vivo

Papanikolaou et al. show that deep-layer cortical neurons exhibit abnormally prolonged Ca2+ transients early in Alzheimer’s mouse models. This is linked to suppressed activity and altered tuning of fa...

cell.com

Please welcome our official #mesoSPIM channel on this platform, @mesospim.bsky.social. Repost is appreciated!