Thrilled to be part of the UEG Council Meeting today! UEG is an incredibly vibrant community bringing together experts from across all fields of gastroenterology. Really excited for the opportunities ahead! @myueg.bsky.social
Enrique de-Madaria
@demadaria.bsky.social
Passionate about clinical research. Gastroenterologist, pancreatologist. Alicante, Spain
In this new episode of the UEG Podcast, Pradeep Mundre and Jeroen Dekervel dive into how immunotherapy is changing patient outcomes and the role it plays in cancer management. 🔗 https://bit.ly/44R97K3
Es un placer ver publicado el estudio SIMBA de mi amigo @demadaria.bsky.social Mucho trabajo detras de este estudio. gut.bmj.com/content/earl...
Simvastatin in the prevention of recurrent pancreatitis: a triple-blinded randomised clinical trial (the SIMBA trial)
Background Recurrent acute pancreatitis (RAP) or acute-on-chronic flares in chronic pancreatitis (CP) have limited preventive options beyond addressing the underlying aetiology. Statins, due to their ...
gut.bmj.com
Despite the heralded anti-inflammatory actions of statins, simvastatin had no effect on recurrences of acute or acute on chronic flares of #pancreatitis gut.bmj.com/content/earl...
Simvastatin in the prevention of recurrent pancreatitis: a triple-blinded randomised clinical trial (the SIMBA trial)
Background Recurrent acute pancreatitis (RAP) or acute-on-chronic flares in chronic pancreatitis (CP) have limited preventive options beyond addressing the underlying aetiology. Statins, due to their ...
gut.bmj.com
Don't miss the latest post on my blog #DeMadariaVsPlacebo My strange neighbours To get to my office, I have to walk through an area with strange people who do weird things: BioFab And that has been an opportunity! demadaria.substack.com/p/my-strange...
My strange neighbors
Mis extraños vecinos
demadaria.substack.com
Don't miss the latest entry on my blog He is still there, in Brazil How a French doctor influenced several generations of Brazilian colleagues demadaria.substack.com/p/he-is-stil...
He is still there, in Brazil
Él aun está allí, en Brasil
demadaria.substack.com
9 years in 7 minutes How does it feel when, after 9 years of work, a clinical trial like SIMBA is presented for 7 minutes at a conference? #UEGweek #Berlin Don't miss the latest post on my blog #DeMadariaVsPlacebo demadaria.substack.com/p/9-years-in...
9 years in 7 minutes
9 años en 7 minutos
demadaria.substack.com
Congratulations to our newly elected council members: Silvio Danese, Vice President @iagorlago.bsky.social, Chair Elect Education Committee Chloé Melchior, Research Committee Chair @demadaria.bsky.social, Independent Councillor We are looking forward to working with you!
Don't miss the latest post on my clinical research blog #DeMadariaVsPlacebo The Difficult Decision of the Daruma's Eye When you have to decide which exciting project to focus on demadaria.substack.com/p/the-diffic...
The Difficult Decision of the Daruma’s Eye
La difícil decisión del ojo del Daruma
demadaria.substack.com
Best of @myueg.bsky.social session during the Panamerican Gastroenterology week in Lima, Peru #SPED2025 @maloehr.bsky.social
Don't miss the new post on my blog DeMadaria Vs Placebo. Following the success of How to Get Your Article Rejected and 10 Tricks to Be a Terrible Mentor, here comes How to Fail in Your Collaborative Study. demadaria.substack.com/p/how-to-mak...
How to make your collaborative clinical study fail
Como conseguir que tu estudio clínico colaborativo fracase
demadaria.substack.com
Should GI bleeding/altered mental status be considered organ failure in acute pancreatitis? Pancreatology Our latest publication: This study evaluates the independent associations of GIB and IMS with morbidity and mortality in AP authors.elsevier.com/a/1lYrs53tct...
authors.elsevier.com
Final days for Early Bird Registration! Join the Harvard postgraduate course on pancreatic diseases and bring Harvard to your CV Learn the best and discover brand-new lectures not included in previous editions open.substack.com/pub/demadari...
Bring Harvard to your CV! Last days for early bird registration
Lleva a Harvard a tu CV
open.substack.com
There is a drug called ursodeoxycholic acid that dissolves gallstones. Urso means “bear” in Latin. Why is it called that? Why does our OSOPOLAR (POLAR BEAR) clinical trial have that name? Read my latest blog post 👇🏻👇🏻👇🏻 demadaria.substack.com/p/bile-from-...
Bile from polar bears
La bilis de los osos polares
demadaria.substack.com
🥳👉Very happy to share our latest paper published in Endoscopy 🙌Great team effort from 17 🇪🇺centers PPI 💊 intake lead to ↗️ LAMS occlusion and ↗️ necrosectomy rates addressing WONs but 🩸complication same as No PPI What is your practice? tinyurl.com/2ubsu5u4
How and when do we become infected with Helicobacter pylori? From my blog for patients "The Pitch of The Stomach" thepitofthestomach.substack.com/p/how-and-wh...
How and when do we become infected with Helicobacter pylori?
H. pylori: The Most Common Chronic Infection in Humans — But How Do We Catch It?
thepitofthestomach.substack.com
Just published in @UEGJournal : “How to Survive and Succeed in the Design and Execution of a Collaborative Randomized Controlled Trial” There you have all the tricks I've learned over the last 15 years about how to conduct a multicenter RCT All🦾 onlinelibrary.wiley.com/doi/10.1002/...
How to Survive and Succeed in the Design and Execution of a Collaborative Randomized Controlled Trial
This article guides the design and execution of successful collaborative randomized controlled trials (RCTs). Aimed at researchers looking to impact clinical practice, it highlights the advantages of....
onlinelibrary.wiley.com
1/3 The abstract with the results of WATERLAND, an RCT comparing lactated Ringer's solution vs. normal saline in fluid therapy for acute pancreatitis, has just been submitted to the UEG Week Berlin October 25 @myueg.bsky.social
1/3 Very good news: the second edition of the course "Management of Pancreatic Disorders for the Practicing Clinician" co-directed by Yasmin Hernandez-Barco and myself has just been approved by @harvard.edu
¿Será iluminar el estómago una buena estrategia para tratar la gastroparesia? Resumimos los resultados de un estudio al respecto y su traslación a la práctica clínica 👇👇👇👇 doi.org/10.1111/nmo....
Direct Stimulation of Gastric Smooth Muscle Cells via Gq Proteins With Light
Optogenetic stimulation enables direct and selective stimulation of smooth muscle cells and thus provides a new opportunity to restore gastric contractility in cases of gastroparesis. Herein, we demo...
doi.org
Participating in Chronicity Forlì 2025 invited by my friend Carlo Fabbri #EmiliaRomagna Great talks on promotion of research, basic research in pancreatic cancer. Sharing a nice experience with Carlo's team Chiara, Cecilia, Stefano, Andrea...
In Seoul they give fluid resuscitation to pine trees, I wonder if it is aggressive or moderate
Proud to receive the prize for the best oral presentation of the International Biliary Pancreatic Meeting 2025 in Seoul, validation of PAN-PROMISE score for its application in RCTs in acute pancreatitis Thanks to the scientific committee!
… and so the story continues @demadaria.bsky.social presenting the #Waterfinder study in #acutepancreatitis as a follow-up to the #Waterfall trial to find the optimal fluid resuscitation
Submit your abstract to UEG Week 2025! Present your research at one of Europe’s largest and most influential congresses in gastroenterology – where science meets a truly multidisciplinary and diverse audience from around the world. 📝 Submit your abstract by April 25! https://bit.ly/3WODJci
Special session on the benefits of joining @myueg.bsky.social and attending UEG week, and presentation of the new guidelines on exocrine pancreatic insufficiency during the Seoul 2025 IPBM meeting @maloehr.bsky.social
Finally also showing the results from the #MITIGATE study in #IgG4RD #igg4ward #inebilizumab being approved by @fda.gov now for #IgG4RD !
Excellent talk by @maloehr.bsky.social on advances in autoimmune pancreatitis during Seoul IPBM 2025! @myueg.bsky.social
@demadaria.bsky.social presenting 🧑🏫 #PROM for #acutepancreatitis ie the PAN-PROMISE symptom Score during the #IPBM2025 🇰🇷 as used for the #Waterfall study 📚 . Appears to be very useful! 📉
Honoured to chair the Seoul IPBM 2025 Plenary Session together with Professors Yoo and Cheon, and have an oral presentation there Nice multicenter studies aiming to advance in the biliary-pancreatic field @myueg.bsky.social @aegastro.es @maloehr.bsky.social