A PhD project is available in my new lab to explore how proteins fold in real time as they are synthesised by the ribosome. Feel free to reach out!

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 2w ago

Ready to take the next step in your research career? The LMB is now accepting applications for PhD placements starting in October 2027. Deadline: 08 December 2026 (allow time for reference submission). Discover what we offer here: https://mrclmb.ac.uk/careers-and-people/phd-students/

"Restructuring research funding as a choice between discovery and application gets the economics wrong, the evidence wrong and the people wrong." Great piece. I suspect Richard Jones (on Bsky?) will have views. arxiv.org/abs/2608.00172

Discovery is not the opposite of application

Restructuring research funding as a choice between discovery and application gets the economics wrong, the evidence wrong and the people wrong.

arxiv.org

Now out as a perspective in PLOS Biology. Where next for structural bioinformatics? journals.plos.org/plosbiology/...

Joe Greener@jgreener64.bsky.social · 11mo ago

I wrote a blog post about the future of structural bioinformatics. Where to go after AlphaFold? How do we avoid the field becoming a load of half-baked LLMs? Let me know what you think. jgreener64.github.io/posts/struct...

Very happy to share a new preprint characterising the unfolded state of a folding-competent domain at the cusp of folding initiation on the ribosome. Co-led by @julianstreit.bsky.social from my PhD in John Christodoulou's lab. Many thanks to all the co-authors!

The initiation of de novo protein folding on the ribosome

How the earliest structure within the unfolded state is formed during biosynthesis on the ribosome and whether it has any consequences for downstream folding remain open questions. Here, we combine 15...

biorxiv.org

New online: Structures of protein folding intermediates on the ribosome

Structures of protein folding intermediates on the ribosome

Nature Structural & Molecular Biology, Published online: 16 June 2026; doi:10.1038/s41594-026-01814-7Atomistic structural ensembles of protein folding intermediates on the ribosome are resolved by comprehensive 19F nuclear magnetic resonance analyses integrated with molecular dynamics simulations, providing insights into cotranslational folding pathways.

dlvr.it

Excited to share our work describing structural ensembles of protein folding intermediates on the ribosome is now published in @natsmb.nature.com ! www.nature.com/articles/s41... Very grateful to co-first author @sammyhschan.bsky.social, our supervisor John Christodoulou and all our co-authors.

Structures of protein folding intermediates on the ribosome - Nature Structural & Molecular Biology

Atomistic structural ensembles of protein folding intermediates on the ribosome are resolved by comprehensive 19F nuclear magnetic resonance analyses integrated with molecular dynamics simulations, pr...

nature.com

A bit of news! 😊 I'm delighted to be starting my lab @mrclmb.ac.uk. Protein folding remains one of the most profound puzzles in biology, and we'll be exploring how translation kinetics, the ribosome and chaperones shape this fundamental process. 🧩 Opportunities to join the group coming soon!

MRC Laboratory of Molecular Biology@mrclmb.ac.uk · 4mo ago

The LMB is thrilled to announce the appointment of @ivanabukvin.bsky.social as a Group Leader in the PNAC Division. Beginning in January 2027, Ivana’s group will investigate co-translational folding and misfolding of proteins. Read more: mrclmb.ac.uk/news-events/...

Sigh... the "protein folding problem" ≠ "structure predicition".