I am excited to share that I will be joining the Baker Institute for Animal Health and College of Veterinary Medicine at Cornell University as an Assistant Professor next spring! I am grateful to my mentors and colleagues who have supported me throughout this journey.

Excited to share that my department has an open faculty search for an Assistant Professor! The search is broad, focused on candidates who plan to address fundamental questions in genetics and genomics. The due date is soon: Nov 13. You can apply through interfolio. apply.interfolio.com/190644

A searchable mapping between NIH study sections and program officers that doesn't suck. (Claude one-shot) sashagusev.github.io/po-study-sec...

The September issue of #GENETICS features work from @jonj-udd.bsky.social, @jeffspence.github.io, & Co which determines how genes associated with human recessive disorders fit the predictions of the classic theory of mutation–selection balance. 🔗 buff.ly/v8FpWWA

JOB ALERT: UNC Bio is hiring 2 tenure track assistant profs doing molecular, cell, and dev bio. The search is intentionally broad, so please share widely and spread the word! Find more information and apply here: unc.peopleadmin.com/postings/325... Application review begins Nov 1.

For the last 34 years I have been on the faculty of the UNC-Chapel Hill Department of Biology and have never regretted that decision. This year we are hiring TWO new Assistant Professors in the broad area of Molecular, Cell, Developmental Biology 1/n bio.unc.edu

The Emory Biology department is hiring a tenure-track ecologist at any rank. Deadline is Nov 1, link below! As I've said many times before, I couldn't ask for a more supportive department. Our faculty colleagues, dept chair, and admin staff are truly awesome ❤️ apply.interfolio.com/191783

Exciting news: @uwgenome.bsky.social will be hiring for two tenure-track faculty positions this year, one open rank and one assistant professor. Both are “Genome Sciences” interpreted broadly so we welcome applicants working in a variety of fields and methods. Ad will be out shortly.

Please help spread the word! We are recruiting multiple Postdoctoral Fellows as part of the recently launched Bakar Computational Biomedicine Initiative (BCBI) at UC Berkeley and UCSF. BCBI website: bcbi.berkeley.edu Apply by Nov 1, 2026: berkeley.infoready4.com#freeformComp... (1/n)

📣 We are looking for a PhD student in 2027! Interested in studying rapid evolutionary dynamics of species in changing climates? Apply to the MOI LAB by Nov 19! Flyer below & tinyurl.com/flyerphdmoilab @ucberkeleyofficial.bsky.social @innovativegenomics.bsky.social @hhmi-science.bsky.social

2027_PhD_RapidEvolutionGenomicsEcology-MoiLab_Berkeley-HHMI

PhD positions: Rapid evolutionary genomics in plants Moi Exposito-Alonso Lab — www.moilab.science Assistant Professor, Freeman Hrabowski Scholar HHMI · Department of Integrative Biology · Innovative G...

tinyurl.com

These are of course very old questions with tremendous recent progress; we focus mostly on the recent progress and what it offers for the next era of studying human genetics in biobanks. Excited this preprint is out and we'd of course love to hear any thoughts!

Jeff Spence@jeffspence.github.io · 3w ago

@roshnipatel.bsky.social and I wrote about using biobanks to learn about evolution, and how those findings shape interpretations of association studies. We focused on estimating evolutionary constraint and relating relating selection on variants to selection on traits and include open questions.

@roshnipatel.bsky.social and I wrote about using biobanks to learn about evolution, and how those findings shape interpretations of association studies. We focused on estimating evolutionary constraint and relating relating selection on variants to selection on traits and include open questions.

arXiv q-bio.PE Populations and Evolution@qbiope-bot.bsky.social · 3w ago

Jeffrey P. Spence, Roshni A. Patel: Insights into human evolution from large genetic biobanks https://arxiv.org/abs/2609.12297 https://arxiv.org/pdf/2609.12297 https://arxiv.org/html/2609.12297

Jeffrey P. Spence, Roshni A. Patel: Insights into human evolution from large genetic biobanks https://arxiv.org/abs/2609.12297 https://arxiv.org/pdf/2609.12297 https://arxiv.org/html/2609.12297

The Stengl-Wyer Postdoctoral Scholars Program is a great launch pad for early independence. Supports 3y of research at UT Austin. Inquiries to faculty sponsors welcome! Apply by 12/7/26 biodiversity.utexas.edu/about-center/endowments-biodiversity/stengl-wyer-endowment/stengl-wyer-scholars-program

I’m currently recruiting an experienced postdoc to join our team in Brisbane for at least two years, working on some cutting-edge problems in statistical genomics and genetic epidemiology. Link: uq.wd3.myworkdayjobs.com/en-GB/uqcare...

Job opportunity at Columbia U., in "any combination of field, experimental, computational, or theoretical approaches to study fundamental questions in evolutionary biology".

Andres Bendesky@bendeskylab.com · 3w ago

We have a tenure-track faculty position in Evolutionary Biology in Columbia's E3B Department. Application deadline is October 15. Come be our colleague. Please RT! apply.interfolio.com/193016

We have a tenure-track faculty position in Evolutionary Biology in Columbia's E3B Department. Application deadline is October 15. Come be our colleague. Please RT! apply.interfolio.com/193016

I’m looking to hire an NIH funded postdoc to join our lab here at Davis (please RT). Ongoing areas of interest include: 1) polygenic signals of selection from time series, ARGs, GWAS, etc 2) The interpretation of GWAS, polygenic scores, & sources of confounding

Well this is good news

Chise@sailorrooscout.bsky.social · 3w ago

GOOD NEWS! A personalized mRNA vaccine has SUCCEEDED in keeping melanoma, a deadly skin cancer, from returning. Phase III trial results in MORE THAN 1,100 patients shows the vaccine SIGNIFICANTLY extended the time patients lived without their melanoma returning AND reduced the risk of metastasis.

We are thrilled to share that our GPN-Star manuscript is now published and freely available: doi.org/10.1038/s415... (1/n)

Predicting genome-wide functional constraints with GPN-Star - Nature

GPN-Star, a genomic language model with a phylogeny-aware architecture for whole-genome alignment data, is shown to be a scalable and flexible tool for genetic variant effect prediction across species...

doi.org

Must-know numbers in human genetics -- As many of you know, I'm writing a free online textbook in human genetics. In this blog post I cover a key skill for genome scientists from that book: how to use mental math to figure out key genome properties. jkpritchard.substack.com/p/on-fermi-p...

On Fermi Problems in Human Genetics

and some very useful numbers about human genomes to get you started!

jkpritchard.substack.com

Our work on systematic perturb-seq of primary human T cells is now out in Cell 🎉 www.cell.com/cell/fulltex... It's been a privilege to work with @ronghuizhu.bsky.social between @jkpritch.bsky.social @marsonlab.bsky.social labs, with a dream-team of co-authors ❤️ Highlights in preprint thread👇

Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits

A dynamic atlas of gene regulation was generated by perturbing every expressed gene across 22 million primary human CD4+ T cells under resting conditions and following re-stimulation. The resulting ma...

cell.com

Emma Dann@emmamarydann.bsky.social · 9mo ago

Together with @ronghuizhu.bsky.social, we are thrilled to present our new perturb-seq study of 22M primary CD4+ T cells, across donors and timepoints – the result of a decade-long collaboration between the Marson @marsonlab.bsky.social and Pritchard @jkpritch.bsky.social labs 🧵 tinyurl.com/gwt2025

Genome-scale perturb-seq in human T cells. Our fantastic postdocs @ronghuizhu.bsky.social and @emmamarydann.bsky.social have done great work here to show the power and opportunities of perturb-seq in primary cells. This is part of a wonderful long-term collaboration with @marsonlab.bsky.social

Emma Dann@emmamarydann.bsky.social · last mo.

Our work on systematic perturb-seq of primary human T cells is now out in Cell 🎉 www.cell.com/cell/fulltex... It's been a privilege to work with @ronghuizhu.bsky.social between @jkpritch.bsky.social @marsonlab.bsky.social labs, with a dream-team of co-authors ❤️ Highlights in preprint thread👇

UMass Amherst Dept of Biology is hiring a TT faculty member in Evolutionary Biology! careers.umass.edu/jobs/assista... We have a diverse and wonderful dept - please consider joining us!

Assistant Professor - Evolutionary Biology - Amherst, Massachusetts, United States

Title: Assistant Professor - Evolutionary Biology Executive Area: Academic Affairs College/School/MBU: College of Natural Sciences Department: Biology Work Location: Amherst Schedule: Full Time Work A...

careers.umass.edu

I am delighted to announce that The Department of Human Genetics at the University of Utah is continuing a multi-year recruiting initiative for multiple tenure-track faculty positions at the rank of Assistant Professor. Please share and consider applying! utah.peopleadmin.com/postings/208...

Not my vote but great choice 😎 www.theguardian.com/environment/...

Winner of Invertebrate of the Year 2026 crowned – and it is the size of a grain of rice

The leaf sheep, a neon green solar-powered slug, has inspired at least one Pokémon character and triumphs in global ballot

theguardian.com

I am delighted to present with @hannespetur.bsky.social our new study on the Icelandic pangenome reference HPRC-ICE. This work goes all the way from pangenome construction to disease association! (1/7) www.nature.com/articles/s41...

An Icelandic pangenome reference - Nature

Newly developed methods enable construction of Icelandic haplotypes and mapping of population-scale short reads to a pangenome by reducing reference bias and improving discovery in low-mappability reg...

nature.com

Excited for @gabrielesgarlata.bsky.social’s new preprint on the Genome-Wide Effect of Drift and Selection over a Single Generation 1/n www.biorxiv.org/content/10.6...

The Genome-Wide Effect of Drift and Selection over a Single Generation

The relative importance of genetic drift versus selection to evolutionary change has long been debated. This debate has mainly focused over long-time-scales (e.g. hundreds of thousands of generations)...

biorxiv.org

Congratulations to @dortizba.bsky.social on a new collaborative Tansley Review in @newphyt.bsky.social! Predictive evolutionary genomics: principles, validation, and practice doi.org/10.1111/nph....

So, I've started a substack. I'll be writing about biology, but my first posts are about applying statistical methods to one of my hobbies: track fandom. In the first posts I describe the Pareto trade-off between a fast overall speed and finishing speed: jkpritchard.substack.com/p/greatest-1...

Greatest 1500m races? Fast times vs fast finishes, and the Pareto Frontier.

A statistical analysis of how overall race speed relates to finishing speed.

jkpritchard.substack.com